Dow P Hurst

GPR6 Structural Insights: Homology Model Construction and Docking Studies

Israa H Isawi, Paula Morales, Noori Sotudeh, 2020, Molecules.

The importance of hydrogen bonding and aromatic stacking to the affinity and efficacy of cannabinoid receptor CB2 antagonist, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide (SR144528).

Evangelia Kotsikorou, Herbert H Seltzman, Dow P Hurst, 2013, Journal of medicinal chemistry.

Residues accessible in the binding-site crevice of transmembrane helix 6 of the CB2 cannabinoid receptor.

Dow P Hurst, Patricia H Reggio, N. M. Nebane, 2008, Biochemistry.

Mutation Studies of Ser7.39 and Ser2.60 in the Human CB1 Cannabinoid Receptor: Evidence for a Serine-Induced Bend in CB1 Transmembrane Helix 7

Daniel Fleischer, Mary E Abood, Alexandros Makriyannis, 2007, Molecular Pharmacology.

An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region.

Mary E Abood, Sharon Anavi-Goffer, Dow P Hurst, 2003, Journal of medicinal chemistry.

Structural Basis of G Protein-coupled Receptor-Gi Protein Interaction

Alan Grossfield, Nicholas Leioatts, Dow P Hurst, 2014, The Journal of Biological Chemistry.

A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor*

Tod D Romo, Alan Grossfield, Dow P Hurst, 2010, The Journal of Biological Chemistry.

Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues.

Nicholas H Oberlies, Dow P Hurst, Patricia H Reggio, 2015, Bioorganic & medicinal chemistry.