Gavin Thurston

发表

In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy

Wen Zhang, Ankur Dhanik, Jessica R. Kirshner, 2016, BMC Bioinformatics.

Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition.

Alastair H Kyle, Gavin Thurston, G. Yancopoulos, 2013, Cancer research.

Age-Related Changes in Vascular Endothelial Growth Factor Dependency and Angiopoietin-1–Induced Plasticity of Adult Blood Vessels

Gavin Thurston, D. McDonald, G. Thurston, 2004, Circulation research.

Dll4 Blockade Potentiates the Anti-Tumor Effects of VEGF Inhibition in Renal Cell Carcinoma Patient-Derived Xenografts

Mukund Seshadri, Bryan M. Gillard, Kristopher Attwood, 2014, PloS one.

Dll4-Notch signaling as a therapeutic target in tumor angiogenesis

Gavin Thurston, G. Thurston, F. Kuhnert, 2011, Vascular cell.

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts.

Gavin Thurston, G. Yancopoulos, D. McDonald, 2004, The American journal of pathology.

The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth

Gavin Thurston, G. Yancopoulos, G. Thurston, 2007, Nature Reviews Cancer.

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.

Gavin Thurston, G. Yancopoulos, N. Papadopoulos, 2006, Nature.

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

Gavin Thurston, Hellmut G. Augustin, Gou Young Koh, 2009, Nature Reviews Molecular Cell Biology.

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

Gavin Thurston, Hsin C. Lin, Nicholas W. Gale, 2006, Nature.

Rapid decrease in tumor perfusion following VEGF blockade predicts long-term tumor growth inhibition in preclinical tumor models

Gavin Thurston, Yi Wei, Yi Wei, 2012, Angiogenesis.

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.

Holger Gerhardt, Ivan Lobov, Daniel Nyqvist, 2009, Developmental cell.

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

Gavin Thurston, A. Murphy, G. Yancopoulos, 2004, Proceedings of the National Academy of Sciences of the United States of America.