Klaus-Peter Lesch

发表

Genetic Variation of Serotonin Function and Cognitive Control

Johannes Müller, Alexander Strobel, Thomas Goschke, 2007, Journal of Cognitive Neuroscience.

New Help for Fidgety Philip

Andreas Warnke, Marcel Romanos, Klaus-Peter Lesch, 2008 .

The tricks of the trait: Neural implementation of personality varies with genotype-dependent serotonin levels

Peter M. Jakob, Sebastian Heinzel, Thomas Dresler, 2013, NeuroImage.

Neural response to reward anticipation is modulated by Gray's impulsivity

Felix Breuer, Peter M. Jakob, Ann-Christine Ehlis, 2009, NeuroImage.

How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems

Dennis L. Murphy, Klaus-Peter Lesch, Andrew Holmes, 2008, Neuropharmacology.

Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response.

Volker Arolt, Peter Zwanzger, Katharina Domschke, 2014, The international journal of neuropsychopharmacology.

3,4-Methylenedioxymethamphetamine Self-Administration is Abolished in Serotonin Transporter Knockout Mice

Klaus-Peter Lesch, P. Robledo, K. Lesch, 2007, Biological Psychiatry.

Predicting cortisol stress responses in older individuals: Influence of serotonin receptor 1A gene (HTR1A) and stressful life events

Alexander Strobel, Burkhard Brocke, Clemens Kirschbaum, 2011, Hormones and Behavior.

Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder.

Susanne Walitza, Aribert Rothenberger, Stephan Ripke, 2010, Journal of the American Academy of Child and Adolescent Psychiatry.

Early Life Blockade of 5-Hydroxytryptamine 1A Receptors Normalizes Sleep and Depression-Like Behavior in Adult Knock-Out Mice Lacking the Serotonin Transporter

Daniela Popa, Klaus-Peter Lesch, Véronique Fabre, 2006, The Journal of Neuroscience.

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Laura J. Scott, Naomi R. Wray, Margaret A. Pericak-Vance, 2015, American journal of human genetics.

A functional promoter polymorphism of neuronal nitric oxide synthase moderates prefrontal functioning in schizophrenia.

Ann-Christine Ehlis, Martin Schecklmann, Andreas J Fallgatter, 2011, The international journal of neuropsychopharmacology.

Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter

Dennis L. Murphy, Klaus-Peter Lesch, Andrew Holmes, 2005, Neuropharmacology.

Multicenter Analysis of the SLC6A3/DAT1 VNTR Haplotype in Persistent ADHD Suggests Differential Involvement of the Gene in Childhood and Persistent ADHD

Stefan Johansson, Jan K Buitelaar, Philip Asherson, 2010, Neuropsychopharmacology.

A novel approach to probabilistic biomarker‐based classification using functional near‐infrared spectroscopy

Ann-Christine Ehlis, Thomas Dresler, Tim Hahn, 2012, Human brain mapping.

Regional brain activation changes and abnormal functional connectivity of the ventrolateral prefrontal cortex during working memory processing in adults with attention‐deficit/hyperactivity disorder

Fabio Sambataro, Andreas J Fallgatter, Martin J Herrmann, 2009, Human brain mapping.

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder.

Susanne Walitza, Andreas Warnke, Michael Simons, 2006, The international journal of neuropsychopharmacology.

Discovery of the first genome-wide significant risk loci for ADHD

Jakob Grove, Esben Agerbo, Anders D. Børglum, 2017, bioRxiv.

Regional Differences in Extracellular Dopamine and Serotonin Assessed by In Vivo Microdialysis in Mice Lacking Dopamine and/or Serotonin Transporters

Klaus-Peter Lesch, Kazutaka Ikeda, Hideaki Kobayashi, 2004, Neuropsychopharmacology.

Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation.

Alexander Strobel, Christoph Markert, Burkhard Brocke, 2007, The international journal of neuropsychopharmacology.

Neurovascular coupling in the human visual cortex is modulated by cyclooxygenase-1 (COX-1) gene variant.

Sebastian Heinzel, Tim Hahn, Andreas J Fallgatter, 2011, Cerebral cortex.

The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: Alternative biallelic variation in rhesus monkeys

Annemarie Poustka, Johannes Hebebrand, Klaus-Peter Lesch, 2005, Journal of Neural Transmission.

Mice Lacking the Serotonin Transporter Exhibit 5-HT1A Receptor-Mediated Abnormalities in Tests for Anxiety-like Behavior

Klaus-Peter Lesch, Andrew Holmes, D. Murphy, 2003, Neuropsychopharmacology.

Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative

Dennis L. Murphy, Klaus-Peter Lesch, D. Murphy, 2002, Brain Research.

Functional PAX-6 gene-linked polymorphic region: potential association with paranoid schizophrenia

Michael Knapp, Helmut Beckmann, Klaus-Peter Lesch, 1999, Biological Psychiatry.

Cellular localization and expression of the serotonin transporter in mouse brain

Klaus-Peter Lesch, D. Murphy, K. Lesch, 1997, Brain Research.

Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys

Klaus-Peter Lesch, Stephen J. Suomi, K. Lesch, 2005, Biological Psychiatry.

Serotonin transporter: gene, genetic disorders, and pharmacogenetics.

Alicja Lerner, Klaus-Peter Lesch, D. Murphy, 2004, Molecular interventions.

The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits

Angel Amores, Manfred Schartl, John H. Postlethwait, 2013, Nature Genetics.

Impact of the ADHD-susceptibility gene CDH13 on development and function of brain networks

Barbara Franke, Klaus-Peter Lesch, B. Franke, 2013, European Neuropsychopharmacology.

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Susanne Walitza, Aribert Rothenberger, Takeshi Sakurai, 2011, Nature Genetics.

On the role of serotonin and effort in voluntary attention: Evidence of genetic variation in N1 modulation

Alexander Strobel, Klaus-Peter Lesch, K. Lesch, 2011, Behavioural Brain Research.

Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans.

Ann-Christine Ehlis, Alexander Strobel, Annette Hartmann, 2009, Archives of general psychiatry.

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Jianxin Shi, Susmita Datta, Aribert Rothenberger, 2013, Nature Genetics.

Serotonin Depletion Hampers Survival and Proliferation in Neurospheres Derived from Adult Neural Stem Cells

Klaus-Peter Lesch, Peter Riederer, Angelo Luigi Vescovi, 2010, Neuropsychopharmacology.

Allelic Variation of Serotonin Transporter Function Modulates the Brain Electrical Response for Error Processing

Ann-Christine Ehlis, Andreas J Fallgatter, Martin J Herrmann, 2004, Neuropsychopharmacology.

Influence of functional tryptophan hydroxylase 2 gene variation and sex on the startle response in children, young adults, and older adults

Alexander Strobel, Burkhard Brocke, Clemens Kirschbaum, 2010, Biological Psychology.

Meta-Analysis of Genome-Wide Association Studies On Adult Attention-Deficit and Hyperactivity Disorder

Barbara Franke, Klaus-Peter Lesch, Andreas Reif, 2019, European Neuropsychopharmacology.

Association between reward‐related activation in the ventral striatum and trait reward sensitivity is moderated by dopamine transporter genotype

Sebastian Heinzel, Thomas Dresler, Tim Hahn, 2011, Human brain mapping.

Internalizing and externalizing behavior in adult ADHD

Astrid Dempfle, Klaus-Peter Lesch, K. Lesch, 2014, ADHD Attention Deficit and Hyperactivity Disorders.

A functional NOS1 promoter polymorphism interacts with adverse environment on functional and dysfunctional impulsivity

Marika Paaver, Jaanus Harro, Klaus-Peter Lesch, 2011, Psychopharmacology.

Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?

Klaus-Peter Lesch, K. Lesch, R. Mössner, 1998, Biological Psychiatry.

Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women.

Katharina Domschke, Marcella Rietschel, Rolf Fimmers, 2004, The international journal of neuropsychopharmacology.

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

Yang Wang, Patricia Gruner, Won Hee Lee, 2020, bioRxiv.

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

Klaus-Peter Lesch, K. Lesch, J. Waider, 2012, Neuron.

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

Yang Wang, Patricia Gruner, Won Hee Lee, 2020, bioRxiv.

Serotonergic modulation in executive functioning: Linking genetic variations to working memory performance

Alexander Strobel, Klaus-Peter Lesch, Andreas Reif, 2011, Neuropsychologia.

Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety.

Alexander Strobel, Burkhard Brocke, Clemens Kirschbaum, 2009, The international journal of neuropsychopharmacology.

Absence of Thermal Hyperalgesia in Serotonin Transporter-Deficient Mice

Claudia Sommer, Dennis L. Murphy, Klaus-Peter Lesch, 2003, The Journal of Neuroscience.

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Laura J. Scott, Naomi R. Wray, Margaret A. Pericak-Vance, 2015, Nature Neuroscience.

Epigenetically regulated microRNAs in Alzheimer's disease

Klaus-Peter Lesch, Carlos P. Fitzsimons, Gunter Kenis, 2014, Neurobiology of Aging.

Common brain disorders are associated with heritable patterns of apparent aging of the brain

Anders M. Dale, Lars T. Westlye, Mona K. Beyer, 2019, Nature Neuroscience.

Impact of Catechol-O-Methyltransferase on Prefrontal Brain Functioning in Schizophrenia Spectrum Disorders

Ann-Christine Ehlis, Andreas J Fallgatter, Martin J Herrmann, 2007, Neuropsychopharmacology.

Genetic perspectives on the serotonin transporter

Qian Li, Dennis L. Murphy, Klaus-Peter Lesch, 2001, Brain Research Bulletin.

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies

Susanne Walitza, Andreas Warnke, Helmut Schäfer, 2008, Journal of Neural Transmission.

Association of a NOS1 promoter repeat with Alzheimer's disease

Alexander Strobel, Ilaria Guidi, Klaus-Peter Lesch, 2008, Neurobiology of Aging.

Targeting the murine serotonin transporter: insights into human neurobiology

Dennis L. Murphy, Klaus-Peter Lesch, D. Murphy, 2008, Nature Reviews Neuroscience.

Olfactory and gustatory sensitivity in adults with attention-deficit/hyperactivity disorder

Paul Pauli, Klaus-Peter Lesch, Michael Macht, 2011, Attention deficit and hyperactivity disorders.

Panic disorder and a possible treatment approach by means of high-frequency rTMS: A case report

Ann-Christine Ehlis, Thomas Dresler, Andreas J. Fallgatter, 2009, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder: The Role of Rare Variants and Duplications at 15q13.3

Susanne Walitza, Herbert Roeyers, Peter Holmans, 2012, The American journal of psychiatry.