Michael C. Holmes

发表

ZFN-driven gene targeting to correct mouse Prkdc scid deficiency

Steven J. Howe, Juan A. Bueren, Aj Thrasher, 2011 .

Towards Correction of the scid Mouse by Gene Targeting

Christine Kinnon, Steven J. Howe, Adam Roberts, 2010 .

Targeted transgene integration in plant cells using designed zinc finger nucleases

Lei Zhang, Michael C. Holmes, Philip D. Gregory, 2009, Plant Molecular Biology.

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor

Ronald G. Collman, Michael C. Holmes, Colby R. Maldini, 2017, PLoS pathogens.

A Potential Therapy for Beta-Thalassemia (ST-400) and Sickle Cell Disease (BIVV003)

Michael C. Holmes, Lei Zhang, Jeffrey C. Miller, 2018 .

An improved zinc-finger nuclease architecture for highly specific genome editing

Adam James Waite, Michael C. Holmes, Philip D. Gregory, 2007, Nature Biotechnology.

Targeted Correction and Restored Function of the CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells

Michael C. Holmes, Philip D. Gregory, Darrell N. Kotton, 2015, Stem cell reports.

In vivo genome editing restores hemostasis in a mouse model of hemophilia

Hojun Li, Frederic D. Bushman, Katherine A. High, 2011, Nature.

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1

Luigi Naldini, Michael C. Holmes, Chiara Bovolenta, 2017, Science Translational Medicine.