Markus Rapedius

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

James Kramer, David G Strauss, Liudmila Polonchuk, 2020, Toxicology and applied pharmacology.

Complementary automated patch clamp, extracellular field potential and impedance recordings of iPSCs: Safety screening tool box for the future

Michael George, Daniel C. Millard, Niels Fertig, 2016 .

Characterization of iPS Derived Cardiomyocytes in Voltage Clamp and Current Clamp by Automated Patch Clamp

Andrea Brüggemann, Claudia Haarmann, Niels Fertig, 2017 .

A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.

James Kramer, David G Strauss, George Okeyo, 2020, Journal of pharmacological and toxicological methods.

pH-sensitive K(+) channel TREK-1 is a novel target in pancreatic cancer.

Andrea Brüggemann, Markus Rapedius, D. Sauter, 2016, Biochimica et biophysica acta.

Automated Patch Clamp Meets High-Throughput Screening

Michael George, Andrea Brüggemann, Claudia Haarmann, 2016, Journal of laboratory automation.

RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels

Gerhard Klebe, Tobias Craan, Markus Rapedius, 2010, The EMBO journal.

An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery

Michael George, Søren Friis, Andrea Brüggemann, 2018, Expert opinion on drug discovery.