Philippe Vanparys

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ECVAM and Pharmaceuticals

Philippe Vanparys, P. Vanparys, 2002, Alternatives to laboratory animals : ATLA.

3.10. Carcinogenicity

Raffaella Corvi, Barry Phillips, Cyrille Krul, 2005, Alternatives to laboratory animals : ATLA.

3.7. Genotoxicity and Mutagenicity

Raffaella Corvi, Barry Phillips, Cyrille Krul, 2005 .

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Raffaella Corvi, Elizabeth Parry, Lutz Müller, 2007, Mutation research.

Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop.

Andrew Worth, Markus Schulz, Raffaella Corvi, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

A Review of the Implementation of the Embryonic Stem Cell Test (EST)

Aldert Piersma, Vera Rogiers, Horst Spielmann, 2009, Alternatives to laboratory animals : ATLA.

Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test.

Margino Steemans, Philippe Vanparys, A. K. Peters, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Improvement of the Bovine Corneal Opacity and Permeability (BCOP) assay as an in vitro alternative to the Draize rabbit eye irritation test.

Sandra Verstraelen, An Jacobs, Philippe Vanparys, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Dimiter Milushev, Vera Rogiers, Luc Verschaeve, 2018, Archives of Toxicology.

ECVAM prevalidation of three cell transformation assays.

Raffaella Corvi, Sebastian Hoffmann, Makoto Hayashi, 2011, ALTEX.

In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.

Emilio Benfenati, Dimiter Milushev, Vera Rogiers, 2016, Mutagenesis.

Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.

Raffaella Corvi, Sebastian Hoffmann, Makoto Hayashi, 2012, Mutation research.

ECVAM retrospective validation of in vitro micronucleus test (MNT)

Raffaella Corvi, Sebastian Hoffmann, Thomas Hartung, 2008, Mutagenesis.

A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.

David Kirkland, Philippe Vanparys, Lesley Reeve, 2011, Mutation research.

The Practical Application of Three Validated In Vitro Embryotoxicity Tests

Aldert Piersma, Thomas Hartung, Horst Spielmann, 2006, Alternatives to laboratory animals : ATLA.

Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.

Raffaella Corvi, Peter Kasper, Cyrille Krul, 2009, Mutation research.