Neil C. Dalvie

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Developing a strategy for constructing modular biosensors

Joshua N. Leonard, Andrew K. D. Younger, Neil C. Dalvie, 2015 .

Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

Alexandra Bonnyman, John M. Hickey, David B. Volkin, 2020, bioRxiv.

Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

John M. Hickey, David B. Volkin, Laura E. Crowell, 2021, Microbial Cell Factories.

The yeast stands alone: the future of protein biologic production.

Neil C. Dalvie, J. C. Love, K. Love, 2018, Current opinion in biotechnology.

A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2021, bioRxiv.

Identifying Improved Sites for Heterologous Gene Integration Using ATAC-seq

Neil C. Dalvie, J. C. Love, Joseph R. Brady, 2020, ACS synthetic biology.

Engineering Modular Biosensors to Confer Metabolite-Responsive Regulation of Transcription.

Neil C. Dalvie, Austin G. Rottinghaus, Austin G Rottinghaus, 2017, ACS synthetic biology.

Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffii

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2022, bioRxiv.

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2021, Science advances.

Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants

Neil C. Dalvie, J. C. Love, K. Kaur, 2022, Human vaccines & immunotherapeutics.

Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2022, Science Translational Medicine.

RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2022, mSphere.

Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2022, bioRxiv.

SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2022, Science advances.

Simplified Gene Knockout by CRISPR-Cas9-Induced Homologous Recombination

Neil C. Dalvie, J. C. Love, K. Love, 2021, ACS synthetic biology.

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

Laura E. Crowell, Neil C. Dalvie, J. C. Love, 2021, Proceedings of the National Academy of Sciences.

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

Laura E. Crowell, Neil C. Dalvie, J. C. Love, 2021, bioRxiv.

Scalable, methanol-free manufacturing of the SARS-CoV-2 receptor binding domain in engineered Komagataella phaffii

Laura E. Crowell, Neil C. Dalvie, J. C. Love, 2021, bioRxiv.

Comparative genome‐scale analysis of Pichia pastoris variants informs selection of an optimal base strain

Neil C. Dalvie, J. C. Love, Joseph R. Brady, 2019, Biotechnology and bioengineering.

Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii

Laura E. Crowell, Neil C. Dalvie, J. C. Love, 2021, Biotechnology and bioengineering.

Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens

Shaleem I Jacob, Neil C. Dalvie, J. C. Love, 2020, Journal of pharmaceutical sciences.

Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine

Neil C. Dalvie, J. C. Love, Joseph R. Brady, 2020, Journal of pharmaceutical sciences.

On-demand manufacturing of clinical-quality biopharmaceuticals

Yu Wang, Amos E. Lu, Nicholas J. Mozdzierz, 2018, Nature Biotechnology.

Host-informed expression of CRISPR guide RNA for genomic engineering in Komagataella phaffii.

Neil C. Dalvie, J. C. Love, Joseph R. Brady, 2019, ACS synthetic biology.

Development of a platform process for the production and purification of single‐domain antibodies

Laura E Crowell, Laura E. Crowell, Neil C. Dalvie, 2021, Biotechnology and bioengineering.

Modeling of copy number variability in Pichia pastoris

Amos E. Lu, Andrew J. Maloney, Neil C. Dalvie, 2021, Biotechnology and bioengineering.

SARS-CoV-2 RBD dimers elicit response comparable to VLPs in mice

Neil C. Dalvie, Sergio A. Rodriguez-Aponte, L. Tostanoski, 2023, Research Square.

CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome

Neil C. Dalvie, Sergio A. Rodriguez-Aponte, K. Love, 2024, bioRxiv.