Kiran Musunuru

发表

Figure 4, Representative FACS plots illustrating isolation of TALEN expressing hESCs.

Derek T. Peters, Chad A. Cowan, Kiran Musunuru, 2013 .

Figure 2, Example genome editing target site showing TALEN design criteria.

Derek T. Peters, Chad A. Cowan, Kiran Musunuru, 2013 .

Assessing the outcomes of genome editing

Kiran Musunuru, K. Musunuru, 2021 .

CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo—Brief Report

Kiran Musunuru, K. Musunuru, A. Raghavan, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing

Daniel J. Rader, Chad A. Cowan, Kiran Musunuru, 2014, Circulation research.

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

Jing Zhou, Junjie Lu, Benjamin S. Freedman, 2015, Nature Communications.

Programming human pluripotent stem cells into white and brown adipocytes

Rahul C. Deo, Matthias Nahrendorf, Clary B. Clish, 2012, Nature Cell Biology.

Defining the spectrum of alleles that contribute to blood lipid concentrations in humans

Sekar Kathiresan, Marju Orho-Melander, Kiran Musunuru, 2008, Current opinion in lipidology.

In utero CRISPR-mediated therapeutic editing of metabolic genes

Li Li, Kiran Musunuru, Rajan Jain, 2018, Nature Medicine.

In utero gene editing for monogenic lung disease

Kiran Musunuru, E. Morrisey, K. Musunuru, 2019, Science Translational Medicine.

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.

David Bryder, Christian L. Boutwell, Todd M. Allen, 2014, Cell stem cell.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Alberto Piazza, William Matthai, Flora Peyvandi, 2009, Nature Genetics.

In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing

Kiran Musunuru, K. Musunuru, Xiao Wang, 2017, Arteriosclerosis, thrombosis, and vascular biology.

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.

Russ P Carstens, Kiran Musunuru, Chris McDermott-Roe, 2017, Developmental cell.

Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association.

Steven R Houser, Andre Terzic, Kiran Musunuru, 2018, Circulation. Genomic and precision medicine.

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs.

Chad A. Cowan, Kiran Musunuru, K. Musunuru, 2013, Cell stem cell.

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Olle Melander, Eric E. Schadt, Sekar Kathiresan, 2010, Nature.

Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.

Edwin K Silverman, Daniel Bernstein, Kiran Musunuru, 2018, Circulation. Genomic and precision medicine.

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Tom R. Gaunt, Fotios Drenos, Meena Kumari, 2012, American journal of human genetics.

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Christian Gieger, Yusuke Nakamura, Philippe Froguel, 2011, Nature Genetics.

Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9.

Kiran Musunuru, K. Musunuru, Rajat M Gupta, 2014, The Journal of clinical investigation.

Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR / Cas 9 Graphical

David Bryder, Ryan L. Collins, Christian L. Boutwell, 2014 .

HapMap and Mapping Genes for Cardiovascular Disease

Sekar Kathiresan, Kiran Musunuru, S. Kathiresan, 2008, Circulation. Cardiovascular genetics.

Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group.

Christopher J O'Donnell, Robert M Califf, Matthew J Price, 2012, Circulation.

Genetics of Common, Complex Coronary Artery Disease

Sekar Kathiresan, Kiran Musunuru, S. Kathiresan, 2019, Cell.

Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells

Derek T. Peters, Chad A. Cowan, Kiran Musunuru, 2016, Development.

Clinical and research applications of carotid intima-media thickness.

Kavita Sharma, Michael J Blaha, Kiran Musunuru, 2009, The American journal of cardiology.

Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3.

Kiran Musunuru, K. Musunuru, Alexandra C Chadwick, 2018, Circulation.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

John Spertus, Markus Perola, Eric Boerwinkle, 2012, The Lancet.

A TALEN genome-editing system for generating human stem cell-based disease models.

Kevin Kim, Eric Banks, Feng Zhang, 2013, Cell stem cell.

A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

Yang Yang, Deirdre McMenamin, Peter Bell, 2016, Nature Biotechnology.