Andrew N. Holding

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ER ChIP-seq on Treatment of Fulvestrant with CTCF Control

Florian Markowetz, Michael J. Guertin, Andrew N. Holding, 2017 .

Novelty in science should not come at the cost of reproducibility

Andrew N. Holding, 2019, The FEBS journal.

ZMIZ1 — A novel Estrogen Receptor co-activator that enhances the growth of ER+ breast cancer

Andrew N. Holding, F. Markowetz, F. Giorgi, 2019 .

Web tools to fight pandemics: the COVID-19 experience

Andrew N. Holding, F. Giorgi, D. Mercatelli, 2020, Briefings Bioinform..

Hekate: Software Suite for the Mass Spectrometric Analysis and Three-Dimensional Visualization of Cross-Linked Protein Samples

Andrew N. Holding, J. Mark Skehel, M. Lamers, 2013, Journal of proteome research.

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein.

Andrew N. Holding, Elaine Stephens, S. Bullock, 2013, Genes & development.

KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice

Edith M. Ross, Andrew N. Holding, F. Markowetz, 2018, Science Translational Medicine.

Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq

Andrew N. Holding, F. Markowetz, A. Cullen, 2018, Nucleic acids research.

Genome-wide Estrogen Receptor-α activation is sustained, not cyclical

Andrew N. Holding, F. Markowetz, A. Cullen, 2018, bioRxiv.

Parallel Factor ChIP Provides Essential Internal Control for Quantitative Differential ChIP-Seq

Andrew N. Holding, F. Markowetz, A. Cullen, 2018 .

Network analysis of ChIP-seq data by VULCAN identifies GRHL2 as a key co-regulator of ERa in luminal breast cancer

Andrew N. Holding, F. Markowetz, F. Giorgi, 2018, bioRxiv.

Title: KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice

Edith M. Ross, Anjana, Andrew N. Holding, 2018 .

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding, F. Markowetz, F. Giorgi, 2019, Genome Biology.

Network analysis of ChIP-seq data by VULCAN identifies GRHL2 as a key co-regulator of ERa in luminal breast cancer

Andrew N. Holding, F. Markowetz, F. Giorgi, 2019, bioRxiv.

Detection of subtype-specific breast cancer surface protein biomarkers via a novel transcriptomics approach

Andrew N. Holding, F. Giorgi, D. Mercatelli, 2021, Bioscience reports.

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein.

Andrew N. Holding, Elaine Stephens, S. Bullock, 2013, Genes & development.

XL-MS: Protein cross-linking coupled with mass spectrometry.

Andrew N. Holding, Andrew N Holding, 2015, Methods.

Title : KHS 101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice

Edith M. Ross, Anjana, Andrew N. Holding, 2018 .

Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair

Andrew N. Holding, M. Lamers, H. Kent, 2013, The EMBO journal.

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

Andrew N. Holding, F. Markowetz, J. Carroll, 2018, Nature Communications.

Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking

Andrew N. Holding, M. G. Montgomery, I. Fearnley, 2015, The Journal of Biological Chemistry.

Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

Andrew N. Holding, F. Markowetz, L. Vermeulen, 2020, Cancer cell international.

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding, F. Markowetz, F. Giorgi, 2019, Genome Biology.

Copy of VULCAN paper-Google Docs

Andrew N. Holding, F. Markowetz, F. Giorgi, 2019 .

Conversion of hydroxyphenylpyruvate dioxygenases into hydroxymandelate synthases by directed evolution

Andrew N. Holding, H. O’Hare, F. Huang, 2006, FEBS letters.

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

Andrew N. Holding, F. Markowetz, J. Carroll, 2018, Nature Communications.

A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis

Andrew N. Holding, C. Bakal, E. Rakha, 2023, bioRxiv.

Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq

Michael J. Guertin, Andrew N. Holding, F. Markowetz, 2018, Nucleic acids research.

Novel Quantitative ChIP-seq Methods Measure Absolute Fold-Change in ER Binding Upon Fulvestrant Treatment

Michael J. Guertin, Andrew N. Holding, F. Markowetz, 2017, bioRxiv.

VULCAN: Network Analysis of ER-α activation reveals reprogramming of GRHL2

Andrew N. Holding, F. Markowetz, F. Giorgi, 2022 .

Identification of robust RT-qPCR reference genes for studying changes in gene expression in response to hypoxia in breast cancer cell lines

Andrew N. Holding, W. Brackenbury, Katherine S. Bridge, 2024, bioRxiv.

HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease

Andrew N. Holding, Guanlin Wang, A. S. Mason, 2024, bioRxiv.