Andrew D McCulloch

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Optimization Framework for Patient-Specific Cardiac Modeling

Baskar Ganapathysubramanian, Adarsh Krishnamurthy, Joshua Mineroff, 2019, Cardiovascular Engineering and Technology.

Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research.

Farshid Guilak, Perumal Nithiarasu, Ahmet Erdemir, 2018, Journal of biomechanical engineering.

Integrative biological modelling in silico.

Andrew D McCulloch, Gary Huber, A. McCulloch, 2002, Novartis Foundation symposium.

Multi-core CPU or GPU-accelerated Multiscale Modeling for Biomolecular Complexes

Andrew D McCulloch, Yongjie Zhang, Michael Holst, 2013, Molecular Based Mathematical Biology.

3D printed micro-scale force gauge arrays to improve human cardiac tissue maturation and enable high throughput drug testing.

Min Tang, Andrew D McCulloch, Shaochen Chen, 2019, Acta biomaterialia.

Systems approaches and algorithms for discovery of combinatorial therapies.

Jorge Cortes, Carlo Piermarocchi, Giovanni Paternostro, 2009, Wiley interdisciplinary reviews. Systems biology and medicine.

Biomechanics simulations using cubic Hermite meshes with extraordinary nodes for isogeometric cardiac modeling

Adarsh Krishnamurthy, W. Paul Segars, Andrew D McCulloch, 2016, Comput. Aided Geom. Des..

Electromechanical model of cardiac resynchronization in the dilated failing heart with left bundle branch block.

Andrew D McCulloch, Taras P Usyk, 2003, Journal of electrocardiology.

A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Kevin R. DeMarco, Ilkay Altintas, Rommie E. Amaro, 2019, PLoS Comput. Biol..

Laminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium.

Andrew D McCulloch, Kevin D Costa, A. McCulloch, 1999, American journal of physiology. Heart and circulatory physiology.

Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes

Lili X. Peng, Andrew D McCulloch, Roger Y Tsien, 2006, Proceedings of the National Academy of Sciences.

Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy.

Andrew D McCulloch, A. McCulloch, J. Omens, 2003, American journal of physiology. Heart and circulatory physiology.

Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype

Andrew D McCulloch, Stuart G Campbell, A. McCulloch, 2011, Journal of The Royal Society Interface.

Mechanical discoordination increases continuously after the onset of left bundle branch block despite constant electrical dyssynchrony in a computational model of cardiac electromechanics and growth.

Andrew D McCulloch, A. McCulloch, J. Omens, 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Structural contributions to fibrillatory rotors in a patient-derived computational model of the atria.

Andrew D McCulloch, Wouter-Jan Rappel, Sanjiv M Narayan, 2014, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Functionally and structurally integrated computational modeling of ventricular physiology.

Andrew D McCulloch, A. McCulloch, 2004, The Japanese journal of physiology.

Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart.

Andrew D McCulloch, James W Covell, Jeffrey H Omens, 2007, American journal of physiology. Heart and circulatory physiology.

Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers.

Masahiko Hoshijima, Andrew D McCulloch, Sangeeta N Bhatia, 2003, Biotechnology and bioengineering.

Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation.

Andrew D McCulloch, Jeffrey J Saucerman, A. McCulloch, 2004, Progress in biophysics and molecular biology.

An ionic model of stretch-activated and stretch-modulated currents in rabbit ventricular myocytes.

Andrew D McCulloch, S. N. Healy, A. McCulloch, 2005, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

The role of mechanoelectric feedback in vulnerability to electric shock.

Viatcheslav Gurev, Andrew D McCulloch, Natalia A Trayanova, 2008, Progress in biophysics and molecular biology.

Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes.

Andrew D McCulloch, A. McCulloch, J. Omens, 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.

Andrew D McCulloch, Stuart G Campbell, A. McCulloch, 2014, American journal of physiology. Heart and circulatory physiology.

Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy.

Masahiko Hoshijima, Andrew D McCulloch, Kenneth R Chien, 2005, Journal of molecular and cellular cardiology.

Novel role for vinculin in ventricular myocyte mechanics and dysfunction.

Adarsh Krishnamurthy, Masahiko Hoshijima, Andrew D McCulloch, 2013, Biophysical journal.

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes.

Andrew D McCulloch, Donald M Bers, Eleonora Grandi, 2016, Journal of molecular and cellular cardiology.

Determination of three‐dimensional ventricular strain distributions in gene‐targeted mice using tagged MRI

Andrew D McCulloch, Lawrence R Frank, A. McCulloch, 2010, Magnetic resonance in medicine.

Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes.

Andrew D McCulloch, A. McCulloch, J. Omens, 2008, Biophysical journal.

Three-dimensional residual strain in midanterior canine left ventricle.

Andrew D McCulloch, Karen May-Newman, Kevin D Costa, 1997, American journal of physiology. Heart and circulatory physiology.

Microstructured Cocultures of Cardiac Myocytes and Fibroblasts: A Two-Dimensional In Vitro Model of Cardiac Tissue

Andrew D McCulloch, Peter Kohl, Patrizia Camelliti, 2005, Microscopy and Microanalysis.

Policy needs and options for a common approach towards modelling and simulation of human physiology and diseases with a focus on the virtual physiological human.

Marco Viceconti, Andrew D McCulloch, 2011, Studies in health technology and informatics.

Role of diastolic properties in the transition to failure in a mouse model of the cardiac dilatation.

Andrew D McCulloch, Lawrence R Frank, A. McCulloch, 2006, American journal of physiology. Heart and circulatory physiology.

A single strain-based growth law predicts concentric and eccentric cardiac growth during pressure and volume overload.

Roy C. P. Kerckhoffs, Andrew D McCulloch, A. McCulloch, 2012, Mechanics research communications.

Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium

Andrew D McCulloch, Peter Kohl, Patrizia Camelliti, 2006, Nature Protocols.

Cardiac Systems Biology

Giovanni Paternostro, Andrew D McCulloch, A. McCulloch, 2005, Annals of the New York Academy of Sciences.

Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle

Andrew D McCulloch, Donald M Bers, Eleonora Grandi, 2014, Circulation. Arrhythmia and electrophysiology.

Structural and functional roles of desmin in mouse skeletal muscle during passive deformation.

Andrew D McCulloch, Evelyn Ralston, Richard L Lieber, 2004, Biophysical journal.

Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease.

Andrew D McCulloch, Francisco Torrent-Guasp, Mark Doyle, 2004, Circulation.

Computational modeling for bedside application.

Roy C. P. Kerckhoffs, Andrew D McCulloch, Sanjiv M Narayan, 2008, Heart failure clinics.

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

Andrew D McCulloch, Richard L Moss, Ju Chen, 2012, The Journal of clinical investigation.

Modeling beta-adrenergic control of cardiac myocyte contractility in silico.

Andrew D McCulloch, Jeffrey J Saucerman, A. McCulloch, 2003, The Journal of biological chemistry.

Modelling cardiac calcium sparks in a three‐dimensional reconstruction of a calcium release unit

Zeyun Yu, Masahiko Hoshijima, J Andrew McCammon, 2012, The Journal of physiology.

Muscle LIM protein deficiency leads to alterations in passive ventricular mechanics.

Andrew D McCulloch, Taras P Usyk, A. McCulloch, 2002, American Journal of Physiology. Heart and Circulatory Physiology.

Computational modeling of subcellular transport and signaling.

Andrew D McCulloch, Johan Hake, Peter M Kekenes-Huskey, 2014, Current opinion in structural biology.

Coupling of adjacent tropomyosins enhances cross-bridge-mediated cooperative activation in a markov model of the cardiac thin filament.

Andrew D McCulloch, Kenneth S Campbell, Stuart G Campbell, 2010, Biophysical journal.

Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback.

Andrew D McCulloch, A. McCulloch, J. Omens, 2014, Journal of biomechanical engineering.

Tissue engineering of biological cardiovascular system surrogates.

Andrew D McCulloch, Mark Eastwood, Andrew B Harris, 2002, Heart, lung & circulation.