Stephen Lam

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Automated tissue m-FISH analysis workstation for identification of clonally related cells

Calum MacAulay, Piotr Dubrowski, Wan L. Lam, 2008, SPIE BiOS.

Detection of lung cancer by ratio fluorometry with and without Photofrin II

Branko Palcic, Jaclyn Y. Hung, Stephen Lam, 1990, Photonics West - Lasers and Applications in Science and Engineering.

In Vivo Real-time Endoscopic Raman Spectroscopy for Improving Early Lung Cancer Detection

Haishan Zeng, Guannan Chen, Jianhua Zhao, 2015 .

Laser-induced fluorescence spectroscopy at endoscopy: tissue optics, Monte Carlo modeling, and in vivo measurements

Calum MacAulay, Jianan Y. Qu, Branko Palcic, 1995 .

Airway wall thickness assessed using computed tomography and optical coherence tomography.

Stephen Lam, S. Lam, D. Sin, 2008, American journal of respiratory and critical care medicine.

Confocal fluorescence microendoscopy of bronchial epithelium.

Annette McWilliams, Pierre M Lane, Stephen Lam, 2009, Journal of biomedical optics.

Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development

John D. Minna, John Yee, Raj Chari, 2011, PloS one.

Color Fluorescence Ratio for Detection of Bronchial Dysplasia and Carcinoma In situ

Annette McWilliams, Katrien Grunberg, Stephen Lam, 2009, Clinical Cancer Research.

Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE

Raj Chari, Bradley P. Coe, Wan L. Lam, 2010, PloS one.

Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium

Tao Wang, Yun-Chul Hong, John K Field, 2017, PloS one.

Effect of active smoking on the human bronchial epithelium transcriptome

Calum MacAulay, Raj Chari, Stephen Lam, 2007, BMC Genomics.

In vivo Raman spectroscopy for early lung cancer detection

Haishan Zeng, Annette McWilliams, Stephen Lam, 2010, Asia Communications and Photonics Conference and Exhibition.

Malignancy risk estimation of pulmonary nodules in screening CTs: Comparison between a computer model and human observers

Bram van Ginneken, Mathias Prokop, Asger Dirksen, 2017, PloS one.

Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells

Calum MacAulay, John D. Minna, David S. Shames, 2009, PloS one.

Bronchial thermoplasty in asthma: 2-year follow-up using optical coherence tomography

Pierre Lane, Calum MacAulay, Miranda Kirby, 2014, European Respiratory Journal.

A Phase I Study of myo-Inositol for Lung Cancer Chemoprevention

Calum MacAulay, Annette McWilliams, Stephen Lam, 2006, Cancer Epidemiology Biomarkers & Prevention.

The role of autofluorescence bronchoscopy in diagnosis of early lung cancer

Stephen Lam, S. Lam, 2006 .

Longitudinal Computed Tomography and Magnetic Resonance Imaging of COPD: Thoracic Imaging Network of Canada (TINCan) Study Objectives.

Miranda Kirby, Grace Parraga, Stephen Lam, 2014, Chronic obstructive pulmonary diseases.

The effects of radiation dose and CT manufacturer on measurements of lung densitometry.

Stephen Lam, P. Paré, J. Hogg, 2007, Chest.

Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers

Stephen Lam, S. Lam, J. Minna, 2003, International journal of cancer.

A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules

Paul Kearney, Anil Vachani, Leroy Hood, 2013, Science Translational Medicine.

The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus

Corey Nislow, Don D. Sin, Emily A. Vucic, 2016, BMC Pulmonary Medicine.

In vivo Optical Coherence Tomography Imaging of Preinvasive Bronchial Lesions

Calum MacAulay, Annette McWilliams, Victor Yang, 2008, Clinical Cancer Research.

Diagnostic bronchoscopy--current and future perspectives.

Tawimas Shaipanich, Stephen Lam, Kazuhiro Yasufuku, 2013, Journal of thoracic disease.

Development and in vivo test of a miniature Raman probe for early cancer detection in the peripheral lung

Haishan Zeng, Tawimas Shaipanich, Stephen Lam, 2018, Journal of biophotonics.

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

William S. Bush, Bin Zhu, Angeline S. Andrew, 2017, Nature Genetics.

Detection Sensitivity of a Commercial Lung Nodule CAD System in a Series of Pathologically Proven Lung Cancers

Annette McWilliams, Stephen Lam, Myrna C B Godoy, 2008, Journal of thoracic imaging.

Computed Tomography and the Secrets of Lung Nodules

Stephen Lam, John R Mayo, 2015, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes.

Using Laser Raman Spectroscopy to Reduce False Positives of Autofluorescence Bronchoscopies: A Pilot Study

Haishan Zeng, Stephen Lam, S. Lam, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Cost-Effectiveness Analyses of Lung Cancer Screening Strategies Using Low-Dose Computed Tomography: a Systematic Review

Larry D. Lynd, Stephen Lam, S. Lam, 2016, Applied Health Economics and Health Policy.

Optical spectroscopy and imaging for early lung cancer detection: a review.

Haishan Zeng, Annette McWilliams, Stephen Lam, 2004, Photodiagnosis and photodynamic therapy.

Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology

Igor Jurisica, John Yee, Stephen Lam, 2014, BMC Cancer.

Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small‐cell lung cancer cell lines

Calum MacAulay, Luc Girard, Stephen Lam, 2006, Genes, chromosomes & cancer.

Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease.

Miranda Kirby, Anthony Tam, Stephen Lam, 2016, American journal of respiratory and critical care medicine.

Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Emily A. Vucic, Wan L. Lam, Stephen Lam, 2015, Scientific Reports.

Human Cancer Long Non-Coding RNA Transcriptomes

Emily A. Vucic, Wan L. Lam, Stephen Lam, 2011, PloS one.

Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers

Michael Q. Zhang, Yang Xie, Xiaotu Ma, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.

Avrum Spira, Paola Sebastiani, Jeffrey T. Chang, 2013, American journal of respiratory and critical care medicine.

Mechanism of detection of early lung cancer by ratio fluorometry

Branko Palcic, Jaclyn Y. Hung, Stephen Lam, 1991 .

Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

Calum MacAulay, John D. Minna, John Yee, 2010, PLoS medicine.

Screening for lung cancer using low dose computed tomography

Stephen Lam, S. Lam, M. Tammemagi, 2014, BMJ : British Medical Journal.

Increase of sensitivity of sputum cytology using high-resolution image cytometry: field study results.

Calum MacAulay, Branko Palcic, Xiao Rong Sun, 2002, Cytometry.

A Raman cell based on hollow core photonic crystal fiber for human breath analysis.

Haishan Zeng, Annette McWilliams, Stephen Lam, 2014, Medical physics.

DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways.

Avrum Spira, Annette McWilliams, Raj Chari, 2014, American journal of respiratory cell and molecular biology.

MicroRNA Gene Dosage Alterations and Drug Response in Lung Cancer

Carlos E. Alvarez, Raj Chari, Wan L. Lam, 2011, Journal of biomedicine & biotechnology.

The n e w e n g l a n d j o u r n a l of m e d i c i n e

Warren B. Gefter, Don D. Sin, Annette McWilliams, 2011 .

Detection and Localization of Intraepithelial Neoplasia and Invasive Carcinoma Using Fluorescence-Reflectance Bronchoscopy: An International, Multicenter Clinical Trial

Eric Edell, Stephen Lam, S. Lam, 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Quantitative assessment of the airway wall using computed tomography and optical coherence tomography.

Stephen Lam, S. Lam, H. Coxson, 2009, Proceedings of the American Thoracic Society.

PL02.02 Lung Cancer Screenee Selection by USPSTF Versus PLCOm2012 Criteria – Interim ILST Findings

Sam M. Janes, John Yee, Annette McWilliams, 2019, Journal of Thoracic Oncology.

High‐resolution chromosome arm 5p array CGH analysis of small cell lung carcinoma cell lines

Bradley P. Coe, Calum Macaulay, Cathie Garnis, 2005, Genes, chromosomes & cancer.

Innovative molecular and imaging approaches for the detection of lung cancer and its precursor lesions

Calum MacAulay, Annette McWilliams, Stephen Lam, 2002, Oncogene.

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells.

Stephen Lam, S. Lam, J. Hung, 2007, Cancer research.

Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression

Jennifer Beane, Mary E Reid, Stephen Lam, 2017, Clinical Cancer Research.

Malignancy risk estimation of screen-detected nodules at baseline CT: comparison of the PanCan model, Lung-RADS and NCCN guidelines

Bram van Ginneken, Colin Jacobs, Mathias Prokop, 2017, European Radiology.

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

Paul Brennan, John K Field, Xiangjun Xiao, 2018, Carcinogenesis.

Prediction of lung cancer risk at follow-up screening with low-dose CT: a training and validation study of a deep learning method.

Lori Stewart, Yanxun Xu, Heidi Schmidt, 2019, The Lancet. Digital health.

Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada

Heidi Roberts, Don D. Sin, John Yee, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.