David B Volkin

发表

C Russell Middaugh, Jae Hyun Kim, Sangeeta B Joshi, 2016, Journal of pharmaceutical sciences.

Comparative Characterization of Crofelemer Samples Using Data Mining and Machine Learning Approaches With Analytical Stability Data Sets.

C Russell Middaugh, Eric J Deeds, M Laird Forrest, 2017, Journal of pharmaceutical sciences.

Structural characterization of IgG1 mAb aggregates and particles generated under various stress conditions.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2014, Journal of pharmaceutical sciences.

Development of a stable virus-like particle vaccine formulation against Chikungunya virus and investigation of the effects of polyanions.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2013, Journal of pharmaceutical sciences.

Characterization of the physical stability of a lyophilized IgG1 mAb after accelerated shipping-like stress.

Srivalli Telikepalli, C Russell Middaugh, Sangeeta B Joshi, 2015, Journal of pharmaceutical sciences.

An improved methodology for multidimensional high-throughput preformulation characterization of protein conformational stability.

Nathaniel R Maddux, C Russell Middaugh, David B Volkin, 2012, Journal of pharmaceutical sciences.

Comparability assessments of process and product changes made during development of two different monoclonal antibodies.

Bill Pikounis, Sudhir Burman, Alex Ni, 2011, Biologicals : journal of the International Association of Biological Standardization.

Analytical lessons learned from selected therapeutic protein drug comparability studies.

David B Volkin, Anthony Lubiniecki, A. Lubiniecki, 2013, Biologicals : journal of the International Association of Biological Standardization.

Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody.

C Russell Middaugh, David D Weis, Sangeeta B Joshi, 2018, Journal of pharmaceutical sciences.

Linking the solution viscosity of an IgG2 monoclonal antibody to its structure as a function of pH and temperature.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2013, Journal of pharmaceutical sciences.

Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development.

Tim J Kamerzell, C Russell Middaugh, Sangeeta B Joshi, 2011, Advanced drug delivery reviews.

Glassy-state stabilization of a dominant negative inhibitor anthrax vaccine containing aluminum hydroxide and glycopyranoside lipid A adjuvants.

Theodore W Randolph, C Russell Middaugh, Lilia A. Rabia, 2015, Journal of pharmaceutical sciences.

Effect of ionic strength and pH on the physical and chemical stability of a monoclonal antibody antigen-binding fragment.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2013, Journal of pharmaceutical sciences.

Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody.

C Russell Middaugh, David B Volkin, D. Volkin, 2016, The journal of physical chemistry. B.

Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form.

Hui Zhao, Pei Qi, David B Volkin, 2009, Journal of pharmaceutical sciences.

Preformulation studies as an essential guide to formulation development and manufacture of protein pharmaceuticals.

C Russell Middaugh, David B Volkin, D. Volkin, 2002, Pharmaceutical biotechnology.

Application of a high-throughput screening procedure with PEG-induced precipitation to compare relative protein solubility during formulation development with IgG1 monoclonal antibodies.

David B Volkin, J. Alvarez, D. Volkin, 2011, Journal of pharmaceutical sciences.

Comparison of high-throughput biophysical methods to identify stabilizing excipients for a model IgG2 monoclonal antibody: conformational stability and kinetic aggregation measurements.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2012, Journal of pharmaceutical sciences.

Excipients differentially influence the conformational stability and pretransition dynamics of two IgG1 monoclonal antibodies.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2012, Journal of pharmaceutical sciences.

Biophysical characterization and stabilization of the recombinant albumin fusion protein sEphB4-HSA.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2012, Journal of pharmaceutical sciences.

Characterization and stabilization of recombinant human protein pentraxin (rhPTX-2).

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2013, Journal of pharmaceutical sciences.

Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2012, Journal of pharmaceutical sciences.

Improved data visualization techniques for analyzing macromolecule structural changes

C Russell Middaugh, Vidyashankara G. Iyer, Sangeeta B Joshi, 2012, Protein science : a publication of the Protein Society.

Radar chart array analysis to visualize effects of formulation variables on IgG1 particle formation as measured by multiple analytical techniques.

C Russell Middaugh, David B Volkin, D. Volkin, 2013, Journal of pharmaceutical sciences.

High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation.

C Russell Middaugh, David D Weis, Sangeeta B Joshi, 2013, Journal of pharmaceutical sciences.

Compatibility, physical stability, and characterization of an IgG4 monoclonal antibody after dilution into different intravenous administration bags.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2012, Journal of pharmaceutical sciences.

Evaluating the Role of the Air-Solution Interface on the Mechanism of Subvisible Particle Formation Caused by Mechanical Agitation for an IgG1 mAb.

David B Volkin, Prajnaparamita Dhar, D. Volkin, 2016, Journal of pharmaceutical sciences.

A Formulation Development Approach to Identify and Select Stable Ultra-High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities.

C Russell Middaugh, Sangeeta B Joshi, David B Volkin, 2017, Journal of pharmaceutical sciences.

Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.

Theodore W Randolph, C Russell Middaugh, Wim Jiskoot, 2012, Journal of pharmaceutical sciences.

Preformulation characterization of an aluminum salt-adjuvanted trivalent recombinant protein-based vaccine candidate against Streptococcus pneumoniae.

C Russell Middaugh, Vidyashankara G. Iyer, Sangeeta B Joshi, 2012, Journal of pharmaceutical sciences.

Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry.

C Russell Middaugh, John M Hickey, David D Weis, 2013, Journal of pharmaceutical sciences.