Per Artursson

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Theoretical Predictions of Drug Absorption in Drug Discovery and Development

Kristina Luthman, Christel A. S. Bergström, Christel A S Bergström, 2002, Clinical pharmacokinetics.

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Jill Barber, Bhagwat Prasad, Amin Rostami-Hodjegan, 2019, Clinical pharmacology and therapeutics.

Molecular Descriptors Influencing Melting Point and Their Role in Classification of Solid Drugs

Ulf Norinder, Kristina Luthman, Christel A. S. Bergström, 2003, J. Chem. Inf. Comput. Sci..

Global and Local Computational Models for Aqueous Solubility Prediction of Drug-Like Molecules

Ulf Norinder, Kristina Luthman, Christel A. S. Bergström, 2004, J. Chem. Inf. Model..

Inter-laboratory variability in mass spectrometry-based proteomics workflows

Amin Rostami-Hochaghan, Oliver Poetz, Per Artursson, 2017 .

Passive permeability and active transport models for the prediction of oral absorption

Per Artursson, Pär Matsson, S Neuhoff, 2007 .

Molecular Descriptors Influencing Melting Point and Their Role in Classification of Solid Drugs.

Ulf Norinder, Kristina Luthman, Per Artursson, 2003 .

Effects of a new lipid-based drug delivery system on the absorption of low molecular weight heparin (Fragmin) through monolayers of human intestinal epithelial Caco-2 cells and after rectal administration to rabbits

Per Artursson, P. Artursson, L. Lohikangas, 1994 .

Experimental and Computational Screening Models for Prediction of Aqueous Drug Solubility

Ulf Norinder, Kristina Luthman, Christel A. S. Bergström, 2002, Pharmaceutical Research.

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Maria Backlund, Per Artursson, Maria Karlgren, 2017, Journal of pharmaceutical sciences.

Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat

Peter Gennemark, Rasmus Jansson-Löfmark, Per Artursson, 2012, Journal of Pharmacokinetics and Pharmacodynamics.

Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker of MDR1-dependent drug efflux activity.

Per Artursson, Staffan Tavelin, P. Artursson, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)

Ulf Norinder, Christel A. S. Bergström, Christel A S Bergström, 2007, Journal of Pharmacology and Experimental Therapeutics.

Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition.

Li Di, Manfred Kansy, Kiyohiko Sugano, 2014, Molecular pharmaceutics.

Rapid measurement of intracellular unbound drug concentrations.

Per Artursson, André Mateus, Pär Matsson, 2013, Molecular pharmaceutics.

Structural and conformational determinants of macrocycle cell permeability.

Ulf Norinder, Christian Tyrchan, Giovanni Muncipinto, 2016, Nature chemical biology.

Molecular characteristics for solid-state limited solubility.

Christel A. S. Bergström, Christel A S Bergström, Per Artursson, 2008, Journal of medicinal chemistry.

Expression of 36 drug transporter genes in human intestine, liver, kidney, and organotypic cell lines

Per Artursson, P. Artursson, A. Ungell, 2007 .

Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.

Maria Backlund, Per Artursson, Maria Karlgren, 2016, Journal of pharmaceutical sciences.

A Drug Absorption Model Based on the Mucus Layer Producing Human Intestinal Goblet Cell Line HT29-H

Per Artursson, P. Artursson, J. Karlsson, 1993, Pharmaceutical Research.

Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)

Christel A. S. Bergström, Per Artursson, Pär Matsson, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Prediction of Membrane Permeability to Peptides from Calculated Dynamic Molecular Surface Properties

Kristina Luthman, Patric Stenberg, Per Artursson, 1999, Pharmaceutical Research.

Prediction of the Intestinal Absorption of Endothelin Receptor Antagonists Using Three Theoretical Methods of Increasing Complexity

J. D. Elliott, Kristina Luthman, Harma Ellens, 1999, Pharmaceutical Research.

Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA method

Per Artursson, Sibylle Neuhoff, Alex Avdeef, 2005 .

An Improved Cell Culture Model Based on 2/4/A1 Cell Monolayers for Studies of Intestinal Drug Transport: Characterization of Transport Routes

Per Artursson, Staffan Tavelin, P. Artursson, 2003, Pharmaceutical Research.

pH-Dependent Bidirectional Transport of Weakly Basic Drugs Across Caco-2 Monolayers: Implications for Drug–Drug Interactions

Ismael Zamora, Per Artursson, Sibylle Neuhoff, 2003, Pharmaceutical Research.

Impact of Extracellular Protein Binding on Passive and Active Drug Transport Across Caco-2 Cells

Ismael Zamora, Per Artursson, Sibylle Neuhoff, 2005, Pharmaceutical Research.

Coexistence of passive and carrier-mediated processes in drug transport

Li Di, Gerhard F. Ecker, Manfred Kansy, 2010, Nature Reviews Drug Discovery.

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.

Mark McAllister, René Holm, Christel A. S. Bergström, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Richard Svensson, Robert Gustafsson, Hanna Axelsson, 2014, Nature.

Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues.

Istvan Toth, Per Artursson, Alun Jones, 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.

Richard Svensson, Christian Sköld, Per Artursson, 2013, Journal of medicinal chemistry.

Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2)

Lisbeth Illum, Per Artursson, P. Artursson, 1994, Pharmaceutical Research.

In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions

Richard Svensson, Christel A. S. Bergström, Per Artursson, 2011, Pharmaceutical Research.

Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines

Per Artursson, P. Artursson, A. Ungell, 2007, Drug Metabolism and Disposition.

A Novel Approach for Prediction of Intestinal Absorption of Drugs in Humans based on Hydrogen Bond Descriptors and Structural Similarity

James W. McFarland, Oleg A. Raevsky, Per Artursson, 2001 .

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Richard Svensson, Giovanni Muncipinto, Fabrizio Giordanetto, 2014, Journal of medicinal chemistry.

Intestinal Drug Absorption and Metabolism in Cell Cultures: Caco-2 and Beyond

Per Artursson, Ronald T. Borchardt, P. Artursson, 1997, Pharmaceutical Research.

Selective Paracellular Permeability in Two Models of Intestinal Absorption: Cultured Monolayers of Human Intestinal Epithelial Cells and Rat Intestinal Segments

Per Artursson, P. Artursson, A. Ungell, 1993, Pharmaceutical Research.

Theoretical Calculation and Prediction of Caco-2 Cell Permeability Using MolSurf Parametrization and PLS Statistics

Ulf Norinder, Per Artursson, P. Artursson, 1997, Pharmaceutical Research.

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

Ulf Norinder, Christel A. S. Bergström, Per Artursson, 2009, Pharmaceutical Research.

Prediction of the Oral Absorption of Low-Permeability Drugs Using Small Intestine-Like 2/4/A1 Cell Monolayers

Per Artursson, Staffan Tavelin, S. Chong, 2003, Pharmaceutical Research.

Transport of Lipophilic Drug Molecules in a New Mucus-Secreting Cell Culture Model Based on HT29-MTX Cells

Patric Stenberg, Per Artursson, Thomas Kissel, 2001, Pharmaceutical Research.

pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers.

Ismael Zamora, Per Artursson, Sibylle Neuhoff, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Intestinal Absorption: The Role of Polar Surface Area

Christel A. S. Bergström, Per Artursson, 2003 .

Exploring the role of different drug transport routes in permeability screening.

Ulf Norinder, Christel A. S. Bergström, Christel A S Bergström, 2005, Journal of medicinal chemistry.

Chitosans as Absorption Enhancers for Poorly Absorbable Drugs. 1: Influence of Molecular Weight and Degree of Acetylation on Drug Transport Across Human Intestinal Epithelial (Caco-2) Cells

Per Artursson, P. Artursson, K. Vårum, 1996, Pharmaceutical Research.

Drug bioavailability : estimation of solubility, permeability, absorption and bioavailability

Han van de Waterbeemd, Hans Lennernäs, Per Artursson, 2003 .

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

Ulf Norinder, Jacek R. Wisniewski, Per Artursson, 2012, Journal of medicinal chemistry.

Caco-2 monolayers in experimental and theoretical predictions of drug transport1PII of original article: S0169-409X(96)00415-2. The article was originally published in Advanced Drug Delivery Reviews 22 (1996) 67–84.1

Kristina Luthman, Per Artursson, K. Luthman, 2001 .

An Overview of Caco‐2 and Alternatives for Prediction of Intestinal Drug Transport and Absorption

Per Artursson, P. Artursson, A. Ungell, 2008 .

A modified physiological BCS for prediction of intestinal absorption in drug discovery.

N. M. Zaki, Christel A. S. Bergström, Christel A S Bergström, 2010, Molecular pharmaceutics.

Permeability of 5-fluorouracil and prodrugs in Caco-2 cell monolayers

Per Artursson, Anders Buur, Lars Trier, 1996 .