Francisca Vazquez

发表

Abstract 2690: Massively parallel multiplexed methods to screen hundreds of barcoded cancer cell line models with small molecules or genetic perturbations using next-generation sequencing

Todd R. Golub, John G. Doench, Aviad Tsherniak, 2019 .

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

Todd R. Golub, Aviad Tsherniak, Joshua M. Dempster, 2018, bioRxiv.

Abstract B44: Emerging targets from Cancer Dependency Map v0.1

Todd R. Golub, Aviad Tsherniak, David E. Root, 2017 .

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

Aviad Tsherniak, Joshua M. Dempster, William C Hahn, 2018, Nature Communications.

Abstract PR02: Towards a Cancer Dependency Map

Todd R. Golub, Aviad Tsherniak, David E. Root, 2017 .

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens.

Aviad Tsherniak, Joseph A Marsh, William C Hahn, 2018, Cell systems.

Mutational processes shape the landscape of TP53 mutations in human cancer

Aviad Tsherniak, Gad Getz, Ted Sharpe, 2018, Nature Genetics.

Novel Mechanism of PTEN Regulation by Its Phosphatidylinositol 4,5-Bisphosphate Binding Motif Is Critical for Chemotaxis*

Francisca Vazquez, F. Vazquez, P. Devreotes, 2004, Journal of Biological Chemistry.

Regulation of PTEN Function as a PIP3 Gatekeeper Through Membrane Interaction

Francisca Vazquez, F. Vazquez, P. Devreotes, 2006, Cell cycle.

Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

Aviad Tsherniak, Gavin Ha, William C Hahn, 2017, Cancer discovery.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis.

Francisca Vazquez, F. Vazquez, P. Devreotes, 2005, Developmental cell.

An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer

X. Shirley Liu, Hyunjin Shin, Shuji Ogino, 2013, Oncogene.

Characterizing genomic alterations in cancer by complementary functional associations

Gabriela Alexe, Chiara Romualdi, Pablo Tamayo, 2016, Nature Biotechnology.

TSC2 regulates VEGF through mTOR-dependent and -independent pathways.

William R Sellers, Francisca Vazquez, W. Sellers, 2003, Cancer cell.

Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

Francisca Vazquez, William R. Sellers, W. Sellers, 2000, Molecular and Cellular Biology.

Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance

Ken Chen, Chris Sander, Olivier Gevaert, 2016, Molecular Cancer Research.