Chady H Hakim

发表

Automatic characterization of stride parameters in canines with a single wearable inertial sensor

Gang Yao, Dongsheng Duan, Gregory J Jenkins, 2018, PloS one.

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Dongsheng Duan, Feng Zhang, Charles A. Gersbach, 2016, Science.

Ectopic Catalase Expression in Mitochondria by Adeno-Associated Virus Enhances Exercise Performance in Mice

Chady H Hakim, P. Rabinovitch, D. Duan, 2009, PloS one.

Dual AAV Gene Therapy for Duchenne Muscular Dystrophy with a 7-kb Mini-Dystrophin Gene in the Canine Model.

Chady H Hakim, D. Duan, Xiufang Pan, 2017, Human gene therapy.

Questions Answered and Unanswered by the First CRISPR Editing Study in a Canine Model of Duchenne Muscular Dystrophy.

Chady H Hakim, Shi-jie Chen, D. Duan, 2019, Human gene therapy.

Nanotherapy for Duchenne muscular dystrophy.

Chady H Hakim, D. Duan, Chady H. Hakim, 2018, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart.

Chady H Hakim, D. Duan, Xiufang Pan, 2015, Human gene therapy methods.

Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs

Chady H Hakim, D. Duan, Jin-Hong Shin, 2014, Molecular therapy. Methods & clinical development.

Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy.

Chady H Hakim, D. Duan, Xiufang Pan, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Widespread severe myodegeneration in a compound heterozygote female dog with dystrophin deficiency

Chady H Hakim, D. Duan, S. Korte, 2020, Veterinary medicine and science.

in freshly isolated mouse microvascular endothelial cell tubes

Chady H Hakim, Chady H. Hakim, S. Segal, 2011 .

Temperature effects on morphological integrity and Ca²⁺ signaling in freshly isolated murine feed artery endothelial cell tubes.

Chady H Hakim, Chady H. Hakim, S. Segal, 2011, American journal of physiology. Heart and circulatory physiology.

Connexin Isoform Expression in Smooth Muscle Cells and Endothelial Cells of Hamster Cheek Pouch Arterioles and Retractor Feed Arteries

Chady H Hakim, Chady H. Hakim, S. Segal, 2008, Microcirculation.

flow control in hamster cheek pouch dynamics during blood 2+ Arteriolar smooth muscle Ca

Chady H Hakim, J. R. Mauban, M. Rizzo, 2015 .

High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia.

Chady H Hakim, G. Francis, F. Rossi, 2020, Journal of clinical lipidology.

A marginal level of dystrophin partially ameliorates hindlimb muscle passive mechanical properties in dystrophin‐null mice

Chady H Hakim, D. Duan, Chady H. Hakim, 2012, Muscle & nerve.

Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle

Chady H Hakim, D. Duan, Chady H. Hakim, 2012, Muscle & nerve.

Systemic Delivery of Adeno-Associated Viral Vectors in Mice and Dogs.

Chady H Hakim, D. Duan, Y. Yue, 2019, Methods in molecular biology.

Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus.

Chady H Hakim, D. Duan, Xiufang Pan, 2015, Human molecular genetics.

Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice.

Chady H Hakim, D. Duan, D. Burkin, 2013, Journal of applied physiology.

Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice.

Chady H Hakim, D. Duan, Chady H. Hakim, 2013, Journal of applied physiology.

The gRNA vector level determines the outcome of systemic AAV CRISPR therapy for Duchenne muscular dystrophy.

Chady H Hakim, Shi-jie Chen, D. Duan, 2022, Human gene therapy.

The FVB Background Does Not Dramatically Alter the Dystrophic Phenotype of Mdx Mice

Chady H Hakim, D. Duan, N. Wasala, 2015, PLoS currents.

Monitoring murine skeletal muscle function for muscle gene therapy.

Chady H Hakim, D. Duan, Dejia Li, 2011, Methods in molecular biology.

Nitric oxide‐dependent attenuation of noradrenaline‐induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy

Chady H Hakim, D. Duan, Xiufang Pan, 2018, The Journal of physiology.

Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of Duchenne muscular dystrophy.

Chady H Hakim, D. Duan, Y. Yue, 2013, Human molecular genetics.

Dystrophin contains multiple independent membrane-binding domains.

Chady H Hakim, D. Duan, Xiufang Pan, 2016, Human molecular genetics.

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

Chady H Hakim, D. Duan, M. Mcintosh, 2015, Disease Models & Mechanisms.

AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice.

Chady H Hakim, Shi-jie Chen, C. Gersbach, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy

Chady H Hakim, D. Duan, Xiufang Pan, 2017, Molecular therapy. Methods & clinical development.

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

Chady H Hakim, D. Grimm, Shi-jie Chen, 2021, Nature Communications.