Ira Pastan

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Removing T-cell epitopes with computational protein design

David Baker, Chris King, Marion Pepper, 2014, Proceedings of the National Academy of Sciences.

Sequence rearrangement and duplication of double stranded fibronectin cDNA probably occurring during cDNA synthesis by AMV reverse transcriptase and Escherichia coli DNA polymerase I

Ira Pastan, J. B. Fagan, B. de Crombrugghe, 1980, Nucleic Acids Res..

DNA immunization followed by a single boost with cells: a protein-free immunization protocol for production of monoclonal antibodies against the native form of membrane proteins.

Ira Pastan, Giuliana Salvatore, I. Pastan, 2003, Journal of immunological methods.

Immunotoxins in cancer therapy.

Ira Pastan, I. Pastan, R. Kreitman, 1999, Current opinion in investigational drugs.

Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway.

Ira Pastan, Ulrich Brinkmann, I. Pastan, 2006, Proceedings of the National Academy of Sciences of the United States of America.

New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy

James L. Gulley, Ira Pastan, I. Pastan, 2009, Cancer Immunology, Immunotherapy.

The visualization of fluorescent proteins in living cells by video intensification microscopy (VIM)

Ira Pastan, I. Pastan, M. Willingham, 1978, Cell.

Immunotoxin therapy of cancer.

Ira Pastan, I. Pastan, R. Kreitman, 1993, Nature reviews. Cancer.

Humoral Immune Response to Mesothelin in Mesothelioma and Ovarian Cancer Patients

Mitchell Ho, Ira Pastan, Masanori Onda, 2005, Clinical Cancer Research.

Immunotoxin therapy of cancer

Ira Pastan, I. Pastan, D. Fitzgerald, 2006, Nature Reviews Cancer.

Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins

Byungkook Lee, James J. Vincent, Robert Strausberg, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Mesothelin-Targeted Agents in Clinical Trials and in Preclinical Development

Ira Pastan, I. Pastan, R. Kelly, 2012, Molecular Cancer Therapeutics.

The T Cell Receptor γ Chain Alternate Reading Frame Protein (TARP), a Prostate-specific Protein Localized in Mitochondria*

Ira Pastan, I. Pastan, C. Wolfgang, 2004, Journal of Biological Chemistry.

New Monoclonal Antibodies to Mesothelin Useful for Immunohistochemistry, Fluorescence-Activated Cell Sorting, Western Blotting, and ELISA

Mitchell Ho, Ira Pastan, Masanori Onda, 2005, Clinical Cancer Research.

Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.

Mitchel S Berger, Allan H Friedman, James M Provenzale, 2008, Neuro-oncology.

Distinct Roles of Segregated Transmission of the Septo-Habenular Pathway in Anxiety and Fear

Takashi Yamaguchi, Ira Pastan, Takatoshi Hikida, 2013, Neuron.

INTRACEREBRAL INFUSATE DISTRIBUTION BY CONVECTION‐ENHANCED DELIVERY IN HUMANS WITH MALIGNANT GLIOMAS: DESCRIPTIVE EFFECTS OF TARGET ANATOMY AND CATHETER POSITIONING

Christoph Pedain, Allan H Friedman, Raj K Puri, 2007, Neurosurgery.

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A

Ronit Mazor, Ira Pastan, I. Pastan, 2012, Proceedings of the National Academy of Sciences.

Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA

Ira Pastan, Yoshihiko Yamada, J. Maizel, 1980, Cell.

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate.

Byungkook Lee, Yoonsoo Hahn, Ira Pastan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mesothelin, Stereocilin, and Otoancorin are predicted to have superhelical structures with ARM-type repeats

Byungkook Lee, Yoonsoo Hahn, Ira Pastan, 2009, BMC Structural Biology.

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes

Ira Pastan, Masanori Onda, I. Pastan, 2008, Proceedings of the National Academy of Sciences.

Mesothelin: a new target for immunotherapy.

Ira Pastan, I. Pastan, R. Hassan, 2004, Clinical cancer research : an official journal of the American Association for Cancer Research.

Detection and Quantitation of Serum Mesothelin, a Tumor Marker for Patients with Mesothelioma and Ovarian Cancer

Alan T. Remaley, Ira Pastan, Masanori Onda, 2006, Clinical Cancer Research.

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Michael M. Gottesman, Kazumitsu Ueda, Ira Pastan, 1986, Cell.

PRAC2: A new gene expressed in human prostate and prostate cancer

Byungkook Lee, Ira Pastan, I. Pastan, 2003, The Prostate.

Poor correlation between T-cell activation assays and HLA-DR binding prediction algorithms in an immunogenic fragment of Pseudomonas exotoxin A.

Chin-Hsien Tai, Byungkook Lee, Ronit Mazor, 2015, Journal of immunological methods.

Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level.

Byungkook Lee, Yoonsoo Hahn, Ira Pastan, 2008, Cancer research.

Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions.

Raghu Raghavan, Christoph Pedain, Allan H Friedman, 2007, Neuro-oncology.

Increased Affinity and Stability of an Anti-HIV-1 Envelope Immunotoxin by Structure-based Mutagenesis*

Ira Pastan, I. Pastan, D. Hamer, 2002, The Journal of Biological Chemistry.

Evolution and expression of chimeric POTE–actin genes in the human genome

Byungkook Lee, Yoonsoo Hahn, Ira Pastan, 2006, Proceedings of the National Academy of Sciences.

Purification of and Properties of the Cyclic Adenosine 3',5'-Monophosphate Receptor Protein which Mediates Cyclic Adenosine 3',5'-Monophosphate-dependent Gene Transcription in Escherichia coli

Robert L. Perlman, Ira Pastan, I. Pastan, 1971 .

Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity

Rajarshi Guha, Eugen C. Buehler, Ira Pastan, 2015, Proceedings of the National Academy of Sciences.

Pretargeted α Emitting Radioimmunotherapy Using 213Bi 1,4,7,10-Tetraazacyclododecane-N,N′,N″,N‴-Tetraacetic Acid-Biotin

William C Eckelman, Ira Pastan, Chang H Paik, 2004, Clinical Cancer Research.