Nicholas J Timpson

发表

Using multiple genetic variants as instrumental variables for modifiable risk factors

George Davey Smith, Tom M Palmer, Debbie A Lawlor, 2012, Statistical methods in medical research.

The MR-Base platform supports systematic causal inference across the human phenome

Valeriia Haberland, Jack Bowden, Tom R. Gaunt, 2018, eLife.

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Tom R. Gaunt, Klaudia Walter, Nicholas J Timpson, 2015, Nature Communications.

Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis.

Nicholas J Timpson, Gabriel Cuellar-Partida, Simon Haworth, 2020, European journal of human genetics : EJHG.

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

George Davey Smith, Nicholas J Timpson, Frank Dudbridge, 2018, Nature Communications.

Mendelian randomization: where are we now and where are we going?

Stephen Burgess, Shah Ebrahim, Nicholas J Timpson, 2015, International journal of epidemiology.

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS

Christian Gieger, Nicholas J Timpson, Manuel A. R. Ferreira, 2011, Nature Genetics.

Association between polygenic risk scores for attention-deficit hyperactivity disorder and educational and cognitive outcomes in the general population

Nicholas J Timpson, Jon Heron, George Davey Smith, 2016, International journal of epidemiology.

How Does Body Fat Influence Bone Mass in Childhood? A Mendelian Randomization Approach

Nicholas J Timpson, Jonathan H Tobias, Adrian Sayers, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

Philippe Froguel, Nicholas J Timpson, Dirkje S Postma, 2010, Nature Genetics.

Genome‐Wide Association Scan Allowing for Epistasis in Type 2 Diabetes

Nicholas J Timpson, Andrew P Morris, Mark I McCarthy, 2011, Annals of human genetics.

Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable

Debbie A Lawlor, Roger M Harbord, Nicholas J Timpson, 2008, PLoS medicine.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Christian Gieger, Thomas Meitinger, Inês Barroso, 2009, Nature Genetics.

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

Jie Huang, Inês Barroso, Tom R. Gaunt, 2017, American journal of human genetics.

Refining associations between TAS2R38 diplotypes and the 6-n-propylthiouracil (PROP) taste test: findings from the Avon Longitudinal Study of Parents and Children

Nicholas J Timpson, Pauline Emmett, Jon Heron, 2007, BMC Genetics.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2013, Nature Genetics.

Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development.

Nicholas J Timpson, N. Timpson, T. Sørensen, 2015, International journal of epidemiology.

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

Tom M Palmer, Debbie A Lawlor, Nicholas J Timpson, 2013, BMJ.

Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position.

Nicholas J Timpson, Stephen Richmond, John P Kemp, 2012, American journal of human genetics.

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

Thomas Meitinger, Toomas Haller, Andres Metspalu, 2013, American journal of human genetics.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Christian Gieger, Alex Doney, Inês Barroso, 2010, Nature Genetics.

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Peter Kraft, Alexander Teumer, Tom M Palmer, 2015, International journal of epidemiology.

Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI

Shah Ebrahim, Debbie A Lawlor, Nicholas J Timpson, 2009, European Journal of Human Genetics.

Common variants at 6q22 and 17q21 are associated with intracranial volume

Wiro J Niessen, Clifford R Jack, Reinhold Schmidt, 2012, Nature Genetics.

The fat mass- and obesity-associated locus and dietary intake in children.

Nicholas J Timpson, Mark I McCarthy, George Davey Smith, 2008, The American journal of clinical nutrition.

Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

Jackie A Cooper, Meena Kumari, Debbie A Lawlor, 2008, PLoS medicine.

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk

Tom R. Gaunt, Jie Zheng, Nicholas J Timpson, 2017, American journal of human genetics.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2012, Nature Genetics.

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

Nicholas J Timpson, Clive Osmond, Mark I McCarthy, 2013, Human molecular genetics.

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Jie Huang, William J. Astle, Bengt Sennblad, 2016, Nature Genetics.

A genome‐wide approach to children's aggressive behavior: The EAGLE consortium

Nicholas J Timpson, Harald Grallert, René Veenstra, 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort.

Nicholas J Timpson, Jonathan A C Sterne, David M. Evans, 2012, The Journal of allergy and clinical immunology.

Whole-genome sequence-based analysis of thyroid function

Jie Huang, Tom R. Gaunt, Klaudia Walter, 2015, Nature communications.

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease

Tom R. Gaunt, Jie Zheng, Nicholas J Timpson, 2018, Human molecular genetics.

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Hynek Pikhart, Bengt Sennblad, Tom R. Gaunt, 2015, The Lancet.

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Subhajyoti De, Inês Barroso, Philippe Froguel, 2008, Nature Genetics.

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Claude Bouchard, William Wheeler, Peter Kraft, 2014 .