Sami S Zoghbi

发表

Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents

Jeih-San Liow, Christer Halldin, Garth E. Terry, 2008, NeuroImage.

Propofol Decreases In Vivo Binding of 11C-PBR28 to Translocator Protein (18 kDa) in the Human Brain

Peter Herscovitch, Ning Miao, Jin Su Kim, 2013, The Journal of Nuclear Medicine.

11C-Loperamide and Its N-Desmethyl Radiometabolite Are Avid Substrates for Brain Permeability-Glycoprotein Efflux

Jeih-San Liow, Fumihiko Yasuno, Sami S Zoghbi, 2008, Journal of Nuclear Medicine.

11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain

Jeih-San Liow, Shuiyu Lu, Per Svenningsson, 2014, The Journal of Nuclear Medicine.

Metabotropic Glutamate Subtype 5 Receptors Are Quantified in the Human Brain with a Novel Radioligand for PET

Jeih-San Liow, Yasuyuki Kimura, Sami S Zoghbi, 2008, Journal of Nuclear Medicine.

N-desmethyl-Loperamide Is Selective for P-Glycoprotein among Three ATP-Binding Cassette Transporters at the Blood-Brain Barrier

Jeih-San Liow, Christer Halldin, Pavitra Kannan, 2010, Drug Metabolism and Disposition.

11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195

Roger N Gunn, Qi Guo, Masato Kobayashi, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

Jeih-San Liow, Nicholas Seneca, Sami S Zoghbi, 2008, Journal of medicinal chemistry.

Human Brain Imaging and Radiation Dosimetry of 11C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein

Jeih-San Liow, Peter Herscovitch, Nicholas Seneca, 2009, Journal of Nuclear Medicine.

Benzodiazepine receptor distribution in severe intractable tinnitus.

John P Seibyl, Sami S Zoghbi, J. Seibyl, 2004, The international tinnitus journal.

P-Glycoprotein Function at the Blood–Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide

Jeih-San Liow, Peter Herscovitch, Nicholas Seneca, 2010, Journal of Nuclear Medicine.

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.

Francis J McMahon, Nobuyo Kimura, Sami S Zoghbi, 2013, Brain : a journal of neurology.

The PET Radioligand [11C]MePPEP Binds Reversibly and with High Specific Signal to Cannabinoid CB1 Receptors in Nonhuman Primate Brain

Christer Halldin, Fumihiko Yasuno, Eyassu Chernet, 2008, Neuropsychopharmacology.

Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Yasuyuki Kimura, Talakad G. Lohith, Sami S Zoghbi, 2011, The Journal of Nuclear Medicine.

Brain and Whole-Body Imaging of Nociceptin/Orphanin FQ Peptide Receptor in Humans Using the PET Ligand 11C-NOP-1A

Talakad G. Lohith, Sami S Zoghbi, Victor W Pike, 2012, The Journal of Nuclear Medicine.

Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques.

Lisheng Cai, Jeih-San Liow, Nicholas Seneca, 2007, Nuclear medicine and biology.

Increased Permeability-Glycoprotein Inhibition at the Human Blood–Brain Barrier Can Be Safely Achieved by Performing PET During Peak Plasma Concentrations of Tariquidar

Ritwik Bhatia, Sami S Zoghbi, Victor W Pike, 2015, The Journal of Nuclear Medicine.

Effect of a P‐glycoprotein inhibitor, cyclosporin A, on the disposition in rodent brain and blood of the 5‐HT1A receptor radioligand, [11C](R)‐(––)‐RWAY

Jeih-San Liow, Shuiyu Lu, Sami S Zoghbi, 2007, Synapse.

Improved Models for Plasma Radiometabolite Correction and their Impact on Kinetic Quantification in PET Studies

Alessandra Bertoldo, Matteo Tonietto, Gaia Rizzo, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.

Shuiyu Lu, Sami S Zoghbi, Victor W Pike, 2009, Journal of medicinal chemistry.

Synthesis and simple 18F-labeling of 3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a high affinity radioligand for imaging monkey brain metabotropic glutamate subtype-5 receptors with positron emission tomography.

Sami S Zoghbi, Victor W Pike, Robert B Innis, 2007, Journal of medicinal chemistry.

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

Jeih-San Liow, William Charles Kreisl, Sami S Zoghbi, 2015, The Journal of Nuclear Medicine.

Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176—based on recent publications that measured specific-to-non-displaceable ratios

Roger N Gunn, Masato Kobayashi, Sami S Zoghbi, 2017, EJNMMI Research.

On quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human.

Sami S Zoghbi, Victor W Pike, Robert B Innis, 2012, Journal of pharmaceutical sciences.

PET imaging of brain 5-HT1A receptors in rat in vivo with 18F-FCWAY and improvement by successful inhibition of radioligand defluorination with miconazole.

Jeih-San Liow, Masanori Ichise, Jurgen Seidel, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Plasma radiometabolite correction in dynamic PET studies: Insights on the available modeling approaches

Alessandra Bertoldo, Matteo Tonietto, Gaia Rizzo, 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements.

Jeih-San Liow, Masanori Ichise, Sami S Zoghbi, 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1).

Paolo Zanotti-Fregonara, Sami S Zoghbi, Victor W Pike, 2013, Journal of medicinal chemistry.

Quantification of Translocator Protein (18 kDa) in the Human Brain with PET and a Novel Radioligand, 18F-PBR06

Yota Fujimura, Sami S Zoghbi, Victor W Pike, 2009, Journal of Nuclear Medicine.

Imaging D2 Receptor Occupancy by Endogenous Dopamine in Humans

Marc Laruelle, Anissa Abi-Dargham, John P Seibyl, 1997, Neuropsychopharmacology.

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.

Sami S Zoghbi, Victor W Pike, Robert B Innis, 2008, Journal of medicinal chemistry.

The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

Jeih-San Liow, Mattia Veronese, Jinsoo Hong, 2016, The Journal of Nuclear Medicine.