Hiroshi Shimizu

发表

Data science-based modeling of the lysine fermentation process.

Hiroaki Nakai, Fumio Matsuda, Kento Tokuyama, 2020, Journal of bioscience and bioengineering.

Analysis of metabolic network based on conservation of molecular structure

Naoaki Ono, Chikara Furusawa, Hiroshi Shimizu, 2009, Biosyst..

Calculation of optimal trajectories for fermentation processes by genetic algorithm

Suteaki Shioya, Kazuo Matsuura, Ken-ichi Suga, 1993 .

Development of an Automated Culture System for Laboratory Evolution

Chikara Furusawa, Takaaki Horinouchi, Teruaki Minamoto, 2014, Journal of laboratory automation.

On-line estimation and control of apparent extract concentration in low-malt beer fermentation

Suteaki Shioya, Keisuke Nagahisa, Hiroshi Shimizu, 2005 .

¹³C-based metabolic flux analysis of Saccharomyces cerevisiae with a reduced Crabtree effect.

Chikara Furusawa, Fumio Matsuda, Akihisa Kanda, 2015, Journal of bioscience and bioengineering.

Nisin Production by a Mixed-Culture System Consisting of Lactococcus lactis andKluyveromyces marxianus

Suteaki Shioya, Hiroshi Shimizu, H. Shimizu, 1999, Applied and Environmental Microbiology.

Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis.

Yoshio Katakura, Suteaki Shioya, Chikara Furusawa, 2007, Journal of biotechnology.

Comparative study of flux redistribution of metabolic pathway in glutamate production by two coryneform bacteria.

Takashi Gojobori, Suteaki Shioya, Keisuke Nagahisa, 2005, Metabolic engineering.

Image analysis of mycelial morphology in virginiamycin production by batch culture of Streptomyces virginiae

Suteaki Shioya, Ken-ichi Suga, Takuya Nihira, 1996 .

Improvement of L-Lactate Production by CYB2 Gene Disruption in a Recombinant Saccharomyces cerevisiae Strain under Low pH Condition

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2008, Bioscience, biotechnology, and biochemistry.

On-line monitoring of fungal cell concentration by dielectric spectroscopy

Suteaki Shioya, Hiroshi Shimizu, H. Shimizu, 1999 .

ArtPathDesign: rational heterologous pathway design system for the production of nonnative metabolites.

Chikara Furusawa, Hiroshi Shimizu, Sunisa Chatsurachai, 2013, Journal of bioscience and bioengineering.

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

Naoaki Ono, Chikara Furusawa, Tetsuya Yomo, 2010, BMC Genomics.

Reliable Metabolic Flux Estimation in Escherichia coli Central Carbon Metabolism Using Intracellular Free Amino Acids

Chikara Furusawa, Nobuyuki Okahashi, Hiroshi Shimizu, 2014, Metabolites.

Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum

Takashi Hirasawa, Keisuke Nagahisa, Hiroshi Shimizu, 2010, Applied Microbiology and Biotechnology.

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using 13 C metabolic flux analysis

Chikara Furusawa, Hirotada Mori, Takashi Hirasawa, 2012, Microbial Cell Factories.

Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae.

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2009, FEMS yeast research.

Dynamic change in promoter activation during lysine biosynthesis in Escherichia coli cells.

Chikara Furusawa, Tetsuya Yomo, Takashi Hirasawa, 2008, Molecular bioSystems.

Extracting the hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using the self-organizing map: biosynthesis of amino acids

Yoshio Katakura, Suteaki Shioya, Chikara Furusawa, 2007, Applied Microbiology and Biotechnology.

A Vector Library for Silencing Central Carbon Metabolism Genes with Antisense RNAs in Escherichia coli

Katsunori Yoshikawa, Satoshi Ohno, Hiroshi Shimizu, 2013, Applied and Environmental Microbiology.

Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2011, Applied Microbiology and Biotechnology.

Metabolic engineering--integrating methodologies of molecular breeding and bioprocess systems engineering.

Hiroshi Shimizu, H. Shimizu, 2002, Journal of bioscience and bioengineering.

Fuzzy Control of Ethanol Concentration and its Application to Glutathione Production in Yeast Fed-batch Culture

Suteaki Shioya, Hiroshi Shimizu, Keigo Miura, 1992 .

Engineering strategy of yeast metabolism for higher alcohol production

Jun Ishii, Akihiko Kondo, Chikara Furusawa, 2011, Microbial cell factories.

Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling

Takashi Hirasawa, Hiroshi Shimizu, H. Shimizu, 2014, Bioscience, biotechnology, and biochemistry.

Comprehensive phenotypic analysis of single‐gene deletion and overexpression strains of Saccharomyces cerevisiae

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2011, Yeast.

Simultaneous control of apparent extract and volatile compounds concentrations in low-malt beer fermentation

Suteaki Shioya, Keisuke Nagahisa, Hiroshi Shimizu, 2006, Applied Microbiology and Biotechnology.

Metabolic engineering of Synechocystis sp. PCC 6803 for enhanced ethanol production based on flux balance analysis

Katsunori Yoshikawa, Yoshihiro Toya, Hiroshi Shimizu, 2017, Bioprocess and Biosystems Engineering.

Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition.

Takashi Hirasawa, Hiroshi Shimizu, Yuta Matsushima, 2016, The Journal of general and applied microbiology.

(13)C-metabolic flux analysis in S-adenosyl-L-methionine production by Saccharomyces cerevisiae.

Fumio Matsuda, Hiroshi Shimizu, H. Shimizu, 2015, Journal of bioscience and bioengineering.

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2014, Microbial Cell Factories.

Recent advances in amino acid production by microbial cells.

Takashi Hirasawa, Hiroshi Shimizu, H. Shimizu, 2016, Current opinion in biotechnology.

Application of a mathematical model and Differential Evolution algorithm approach to optimization of bacteriocin production by Lactococcus lactis C7

Suteaki Shioya, Sompop Moonchai, Hiroshi Shimizu, 2005, Bioprocess and biosystems engineering.

Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum.

Takashi Hirasawa, Keisuke Nagahisa, Hiroki Sato, 2008, Journal of bioscience and bioengineering.

Production of Glutamate and Glutamate-Related Amino Acids: Molecular Mechanism Analysis and Metabolic Engineering

Takashi Hirasawa, Hiroshi Shimizu, H. Shimizu, 2006 .

Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae

Chikara Furusawa, Katsunori Yoshikawa, Takashi Hirasawa, 2009, Applied Microbiology and Biotechnology.

Computational prediction of impact of rerouting the carbon flux in metabolic pathway on cell growth and nisin production by Lactococcus lactis

Suteaki Shioya, Keisuke Nagahisa, Sunao Egawa, 2006 .

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu, 2009, Microbial cell factories.

Clustering gene expression pattern and extracting relationship in gene network based on artificial neural networks.

Suteaki Shioya, Jihua Huang, Hiroshi Shimizu, 2003, Journal of bioscience and bioengineering.

Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis

Suteaki Shioya, Chikara Furusawa, Keisuke Nagahisa, 2007, Microbial cell factories.

Optimal Production of Glutathione by Controlling the Specific Growth Rate of Yeast in Fed-Batch Culture

Suteaki Shioya, Hiroshi Shimizu, Eizo Sada, 1991 .

Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum

Chikara Furusawa, Takashi Hirasawa, Keisuke Nagahisa, 2009, Applied Microbiology and Biotechnology.