Josephine C. Adams

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Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals

Soren Prag, Josephine C. Adams, Soren Prag, 2003, BMC Bioinformatics.

Artificial Intelligence: Opportunity or Risk?

Jürgen Engel, Josephine C. Adams, 2021, Life and Its Future.

Adhesion networks of cnidarians: a postgenomic view.

Josephine C. Adams, R. Tucker, J. Adams, 2014, International review of cell and molecular biology.

A thrombospondin in the anthozoan Nematostella vectensis is associated with the nervous system and upregulated during regeneration

Josephine C. Adams, J. Hess, R. Tucker, 2012, Biology Open.

Fibronectin inhibits the terminal differentiation of human keratinocytes

Josephine C. Adams, F. Watt, J. Adams, 1989, Nature.

Modelling the early evolution of extracellular matrix from modern Ctenophores and Sponges.

Josephine C. Adams, D. Shoemark, Graham W Draper, 2019, Essays in biochemistry.

Emergence of a Thrombospondin Superfamily at the Origin of Metazoans

Josephine C. Adams, D. Shoemark, Hiroshi Watanabe, 2019, Molecular biology and evolution.

The evolution of the dystroglycan complex, a major mediator of muscle integrity

Josephine C. Adams, A. Brancaccio, J. Adams, 2015, Biology Open.

Natural Risks to Life

Josephine C. Adams, J. Engel, J. Adams, 2021, Life and Its Future.

Prediction and analysis of higher-order coiled-coils: insights from proteins of the extracellular matrix, tenascins and thrombospondins.

Derek N Woolfson, Josephine C. Adams, D. Woolfson, 2013, The international journal of biochemistry & cell biology.

Molecular Phylogeny of a RING E3 Ubiquitin Ligase, Conserved in Eukaryotic Cells and Dominated by Homologous Components, the Muskelin/RanBPM/CTLH Complex

Josephine C. Adams, Ore Francis, Fujun Han, 2013, PloS one.

Bioinformatic analysis of adhesion proteins.

Josephine C. Adams, Josephine C Adams, Juergen Engel, 2007, Methods in molecular biology.

The Evolution of Extracellular Matrix

Josephine C. Adams, S. Özbek, Prakash G. Balasubramanian, 2010, Molecular biology of the cell.

An MBoC Favorite: Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

Josephine C. Adams, J. Adams, 2012, Molecular biology of the cell.

Expression of 01 , 03 , 04 , and 05 Integrins by HumanEpidermal Keratinocytes and Non-Differentiating Keratinocytes

Josephine C. Adams, F. Watt, 2002 .

The thrombospondin type 1 repeat (TSR) superfamily: Diverse proteins with related roles in neuronal development

Josephine C. Adams, R. Tucker, J. Adams, 2000, Developmental dynamics : an official publication of the American Association of Anatomists.

Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-association.

Josephine C. Adams, Soren Prag, G. Collett, 2004, The Biochemical journal.

Functional role of syndecan-1 cytoplasmic V region in lamellipodial spreading, actin bundling, and cell migration.

Josephine C. Adams, Ritu Chakravarti, Vasileia Sapountzi, 2005, Molecular biology of the cell.

Adhesion-modulating/matricellular ECM protein families: a structural, functional and evolutionary appraisal.

Josephine C. Adams, D. Mosher, J. Adams, 2012, Matrix biology : journal of the International Society for Matrix Biology.

The thrombospondin family

Josephine C. Adams, J. Lawler, J. Adams, 1993, Current Biology.

Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites

Josephine C. Adams, D. Hulmes, A. Bonna, 2018, Science Signaling.

Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?

Josephine C. Adams, M. Skacel, Y. Hashimoto, 2005, The international journal of biochemistry & cell biology.

Novel role of the muskelin–RanBP9 complex as a nucleocytoplasmic mediator of cell morphology regulation

Josephine C. Adams, M. Valiyaveettil, Soren Prag, 2008, The Journal of cell biology.

Cell and Molecular Processes in Cancer Metastasis: an AJP-Cell Physiology set of Themed Reviews.

Josephine C. Adams, T. Oskarsson, 2015, American journal of physiology. Cell physiology.

Life on Other Planets

Josephine C. Adams, Jürgen Engel, J. Adams, 2021, Life and Its Future.

Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates

Josephine C. Adams, Ritu Chakravarti, J. Adams, 2006, BMC Genomics.

The thrombospondins.

Josephine C. Adams, J. Lawler, J. Adams, 2011, Cold Spring Harbor perspectives in biology.

Analysis of Fascin-1 in Relation to Gleason Risk Classification and Nuclear ETS-Related Gene Status of Human Prostate Carcinomas: An Immunohistochemical Study of Clinically Annotated Tumours From the Wales Cancer Bank

Josephine C. Adams, A. Clarke, Richard M. Martin, 2017, Biomarkers in cancer.

Adams, J. (2017). Analysis of Fascin-1 in Relation to Gleason Risk Classification and Nuclear ETS-Related Gene Status of Human Prostate Carcinomas: An Immunohistochemical Study of Clinically Annotated Tumours From the Wales Cancer Bank. Biomarkers in Cancer, 9, [1179299X17710944]. https://doi.org/10

Josephine C. Adams, A. Clarke, Richard M. Martin, 2017 .

Clarke, A. R. (2017). Analysis of Fascin-1 in Relation to Gleason Risk Classification and Nuclear ETS-Related Gene Status of Human Prostate Carcinomas: An Immunohistochemical Study of Clinically Annotated Tumours From the Wales Cancer Bank. Biomarkers, 9, [1179299X17710944]. DOI: 10.1177/1179299X177

Josephine C. Adams, A. Clarke, Richard M. Martin, 2017 .

A Role for Syndecan-1 in Coupling Fascin Spike Formation by Thrombospondin-1

Josephine C. Adams, Amanda L. Taylor, Nina Kureishy, 2001, The Journal of cell biology.

Neuronal expression of muskelin in the rodent central nervous system

Josephine C. Adams, M. Kneussel, Sven Loebrich, 2007, BMC Neuroscience.

The roles of fascins in health and disease

Josephine C. Adams, Y. Hashimoto, Dae-Joong Kim, 2011, The Journal of pathology.

Insider trading: Extracellular matrix proteins and their non‐canonical intracellular roles

Josephine C. Adams, Andrew L. Hellewell, J. Adams, 2016, BioEssays : news and reviews in molecular, cellular and developmental biology.

The Thrombospondin Gene Family

Josephine C. Adams, J. Lawler, R. Tucker, 1995 .

AJP-Cell Physiology begins landmark reviews in cell physiology: an editorial from the senior editors of AJP-Cell Physiology.

Josephine C. Adams, E. Delpire, J. Yuan, 2018, American journal of physiology. Cell physiology.

Biological Evolution

Josephine C. Adams, J. Engel, 2021, Life and Its Future.

Trimeric assembly of the C-terminal region of thrombospondin-1 or thrombospondin-2 is necessary for cell spreading and fascin spike organisation.

Josephine C. Adams, D. Mosher, N. Anilkumar, 2002, Journal of cell science.

PDIA3/ERp57 promotes a matrix-rich secretome that stimulates fibroblast adhesion through CCN2

Josephine C. Adams, K. Heesom, M. Jepson, 2022, American journal of physiology. Cell physiology.

Modulation of the extracellular matrix patterning of thrombospondins by actin dynamics and thrombospondin oligomer state

Josephine C. Adams, Elena D. Christofidou, Andrew L. Hellewell, 2015, Bioscience reports.

No Postage Required: Extracellular Vesicles Deliver the Message.

Josephine C. Adams, J. Isenberg, 2019, American journal of physiology. Cell physiology.

Induction of fascin spikes in breast cancer cells by activation of the insulin-like growth factor-I receptor.

Josephine C. Adams, D. Boettiger, M. Guvakova, 2002, The international journal of biochemistry & cell biology.

Expression of fascin-1, the gene encoding the actin-bundling protein fascin-1, during mouse embryogenesis.

Josephine C. Adams, A. De Arcangelis, E. Georges‐Labouesse, 2004, Gene expression patterns : GEP.

Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces

Ning Wang, Donald E Ingber, Kevin Kit Parker, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Impairment of cell adhesion and migration by inhibition of protein disulphide isomerases in three breast cancer cell lines

Josephine C. Adams, Katy A. Jepson, L. McGowan, 2020, Bioscience reports.

Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin‐1

Josephine C. Adams, B. Seed, J. Lawler, 1998, The EMBO journal.

Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors

Josephine C. Adams, M. Skacel, Y. Hashimoto, 2008, BMC Cancer.

The evolution of thrombospondins and their ligand-binding activities.

Josephine C. Adams, A. Bentley, A. A. Bentley, 2010, Molecular biology and evolution.

The thrombospondins.

Josephine C. Adams, J. Lawler, J. Adams, 2004, The international journal of biochemistry & cell biology.

Characterisation of Drosophila thrombospondin defines an early origin of pentameric thrombospondins.

Josephine C. Adams, Ray Monk, S. Baumgartner, 2003, Journal of molecular biology.

Regulation of protrusive and contractile cell-matrix contacts.

Josephine C. Adams, J. Adams, 2002, Journal of cell science.

Matricellular Proteins: Functional Insights From Non-mammalian Animal Models.

Josephine C. Adams, J. Adams, 2018, Current topics in developmental biology.

Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium

Josephine C. Adams, S. Lewis, G. Girotto, 2015, BMC Medical Genomics.

The evolution of tenascins and fibronectin

Josephine C. Adams, R. Tucker, R. Chiquet‐Ehrismann, 2015, Cell adhesion & migration.

Structure of a thrombospondin C‐terminal fragment reveals a novel calcium core in the type 3 repeats

Josephine C. Adams, Marc Kvansakul, E. Hohenester, 2004, The EMBO journal.

Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis

Josephine C. Adams, S. Lewis, Richard M. Martin, 2013, BMC Medicine.

Interaction of fascin and protein kinase Cα: a novel intersection in cell adhesion and motility

Maddy Parsons, Josephine C. Adams, Ray Monk, 2003, The EMBO journal.

Cell–cell and cell–matrix interactions

Josephine C. Adams, K. DeMali, 2012, Molecular Biology of the Cell.

The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course.

Josephine C. Adams, R. Tubbs, D. Hicks, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Functions of the conserved thrombospondin carboxy-terminal cassette in cell-extracellular matrix interactions and signaling.

Josephine C. Adams, J. Adams, 2004, The international journal of biochemistry & cell biology.

Fascin protrusions in cell interactions.

Josephine C. Adams, J. Adams, 2004, Trends in cardiovascular medicine.

Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.

Josephine C. Adams, A. Buda, C. Sarraf, 2003, The American journal of pathology.

Fascins, and their roles in cell structure and function.

Josephine C. Adams, Soren Prag, N. Anilkumar, 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

Roles of fascin in cell adhesion and motility.

Josephine C. Adams, J. Adams, 2004, Current opinion in cell biology.

Molecular organisation of cell–matrix contacts: essential multiprotein assemblies in cell and tissue function

Josephine C. Adams, J. Adams, 2002, Expert Reviews in Molecular Medicine.

Rac regulates the interaction of fascin with protein kinase C in cell migration

Josephine C. Adams, M. Parsons, J. Adams, 2008, Journal of Cell Science.

In the Balance: How do Thrombospondins Contribute to the Cellular Pathophysiology of Cardiovascular Disease?

Josephine C. Adams, A. Pauža, T. Forbes, 2021, American journal of physiology. Cell physiology.

Coronary artery disease and the thrombospondin single nucleotide polymorphisms.

Josephine C. Adams, E. Topol, J. McCarthy, 2004, The international journal of biochemistry & cell biology.

Regulation of post-translational modifications of muskelin by protein kinase C.

Josephine C. Adams, Soren Prag, A. De Arcangelis, 2007, The international journal of biochemistry & cell biology.

Characterization of a Drosophila melanogaster orthologue of muskelin.

Josephine C. Adams, 2002, Gene.

The predicted secretomes of Monosiga brevicollis and Capsaspora owczarzaki, close unicellular relatives of metazoans, reveal new insights into the evolution of the metazoan extracellular matrix.

Josephine C. Adams, Frederike Williams, Hannah A Tew, 2014, Matrix biology : journal of the International Society for Matrix Biology.

Evolution of the Metazoan Extracellular Matrix

Josephine C. Adams, J. Adams, 2013 .

Extracellular Matrix Evolution: An Overview

Josephine C. Adams, J. Adams, 2013 .

PERSPECTIVES The Evolution of Extracellular Matrix

Josephine C. Adams, Prakash G. Balasubramanian, R. Tucker, 2010 .

The RickA protein of Rickettsia conorii activates the Arp2/3 complex

Josephine C. Adams, P. Cossart, Rong Li, 2004, Nature.

Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronectin binding precedes α 5 β 1 integrin loss from the cell surface

Josephine C. Adams, F. Watt, J. Adams, 1990, Cell.

Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis.

Josephine C. Adams, M. Parsons, Y. Hashimoto, 2007, Molecular biology of the cell.

A Rapid, Scalable Method for the Isolation, Functional Study, and Analysis of Cell-derived Extracellular Matrix

Josephine C. Adams, S. Rosini, Andrew L. Hellewell, 2017, Journal of visualized experiments : JoVE.

Phylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation

Josephine C. Adams, S. Chadalavada, Josephine C Adams, 2006, BMC Evolutionary Biology.

Fascin-1 as a biomarker and prospective therapeutic target in colorectal cancer

Josephine C. Adams, J. Adams, 2015, Expert review of molecular diagnostics.

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability

Josephine C. Adams, M. Parsons, A. Jayo, 2012, BMC Biology.

Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region

Josephine C. Adams, E. Hohenester, M. Kvansakul, 2008, Journal of Cell Science.

Stimulation of Fascin Spikes by Thrombospondin-1 Is Mediated by the Gtpases Rac and Cdc42

Josephine C. Adams, M. Schwartz, J. Adams, 2000, The Journal of cell biology.

Functional role of α-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells

Josephine C. Adams, D. Boettiger, M. Guvakova, 2002, Journal of Cell Science.

Membrane-associated collagens with interrupted triple-helices (MACITs): evolution from a bilaterian common ancestor and functional conservation in C. elegans

Josephine C. Adams, T. Pihlajaniemi, Hang-mao Lee, 2015, BMC Evolutionary Biology.

The Kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain.

Josephine C. Adams, 2020, American journal of physiology. Cell physiology.

BIO012468 1..17

Josephine C. Adams, A. Brancaccio, J. Adams, 2015 .

Fascin-1 Promoter Activity Is Regulated by CREB and the Aryl Hydrocarbon Receptor in Human Carcinoma Cells

Josephine C. Adams, Y. Hashimoto, David W. Loftis, 2009, PloS one.

Analysis of α-Dystroglycan/LG Domain Binding Modes: Investigating Protein Motifs That Regulate the Affinity of Isolated LG Domains

Josephine C. Adams, C. Dempsey, A. Brancaccio, 2019, Front. Mol. Biosci..

Methods in cell-matrix adhesion. Introduction.

Josephine C. Adams, 2002, Methods in cell biology.

An evaluation of the evolution of the gene structure of dystroglycan

Josephine C. Adams, A. Brancaccio, J. Adams, 2017, BMC Research Notes.

The Scientific View of the Origin of Life

Josephine C. Adams, Jürgen Engel, J. Adams, 2021, Life and Its Future.

Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

Josephine C. Adams, G. Casey, I. Lavery, 2006, BMC Cancer.

Sharpey‐Schafer, Langley and Sherrington: ‘swordsmen’ of physiology. A historical look to the future

Josephine C. Adams, P. Kohl, A. Stewart, 2023, Experimental physiology.

Intermolecular interactions of thrombospondins drive their accumulation in extracellular matrix

Josephine C. Adams, D. Keene, Elena D. Christofidou, 2015, Molecular biology of the cell.

Physiological reports: Standing openly for sound science

Josephine C. Adams, 2022, Physiological reports.

Human-Made Risks and Climate Change with Global Heating

Josephine C. Adams, Jürgen Engel, J. Adams, 2021, Life and Its Future.

Manipulated Evolution and Artificial Life

Josephine C. Adams, J. Engel, J. Adams, 2021, Life and Its Future.

Revised guidelines to enhance the rigor and reproducibility of research published in American Physiological Society journals.

Josephine C. Adams, C. Sigmund, B. Yates, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

Thrombospondin‐4 is expressed by early osteogenic tissues in the chick embryo

Josephine C. Adams, J. Lawler, J. Adams, 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

An American Physiological Society cross-journal Call for Papers on "Deconstructing organs: Single-cell analyses, decellularized organs, organoids, and organ-on-a-chip models".

Josephine C. Adams, J. Ramirez, A. Marette, 2020, American journal of physiology. Lung cellular and molecular physiology.

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction

Josephine C. Adams, A. Boyle, D. Woolfson, 2018, Scientific Reports.

Molecular evolution of the Thrombospondin superfamily.

Josephine C. Adams, R. Tucker, J. Adams, 2023, Seminars in cell & developmental biology.

Studies of recombinant TWA1 reveal constitutive dimerization

Josephine C. Adams, Ore Francis, P. Race, 2016, Bioscience reports.

Caveat emptor: for researchers, a rose will not smell sweet unless we know its composition

Josephine C. Adams, J. Adams, 2017, Bioscience reports.