Christopher E. Hart

发表

HELM Software for Biopolymers

Tianhong Zhang, Sergio H. Rotstein, Jeff Milton, 2017, Journal of Chemical Information and Modeling.

Mining gene expression data by interpreting principal components

Barbara J. Wold, Diane Trout, Ali Mortazavi, 2006, BMC Bioinformatics.

Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks

Eric Mjolsness, Barbara J. Wold, Christopher E. Hart, 2006, PLoS Comput. Biol..

Clustering analysis of microarray gene expression data by splitting algorithm

Eric Mjolsness, Barbara J. Wold, Ruye Wang, 2003, J. Parallel Distributed Comput..

Gene Expression Clustering with Functional Mixture Models

Padhraic Smyth, Eric Mjolsness, Darya Chudova, 2003, NIPS.

A comparitive framework for understanding clustering results

Eric Mjolsness, Barbara J. Wold, B. Bornstein, 2001 .

A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data

Eric Mjolsness, Barbara J. Wold, Diane Trout, 2005, Nucleic acids research.

Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

Eric E. Swayze, Christopher E. Hart, W. Lima, 2014, Nucleic acids research.

A modular analysis of microglia gene expression, insights into the aged phenotype

Christopher E. Hart, F. Kamme, C. Cho, 2019, BMC Genomics.

Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.

Christopher E. Hart, S. Kuntz, Shuling Guo, 2019, JCI insight.

Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-Induced Goblet Cell Metaplasia in the Adult Murine Lung.

Christopher E. Hart, B. Monia, Guizhen Sun, 2020, American journal of respiratory cell and molecular biology.

Integrated Safety Assessment of 2′-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers

Christopher E. Hart, H. Bui, S. Crooke, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Christopher E. Hart, S. Mukhopadhyay, S. Crooke, 2019, Nature Biotechnology.

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

Christopher E. Hart, S. Freier, M. Sabripour, 2015, Nucleic acids research.

Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

Christopher E. Hart, S. Crooke, S. Damle, 2016, Nucleic acids research.

Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration

Christopher E. Hart, S. Freier, M. Sabripour, 2015, PloS one.

Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells.

Christopher E. Hart, S. Crooke, Xue-hai Liang, 2013, Biochimica et biophysica acta.

Helicos single-molecule sequencing of bacterial genomes.

Christopher E. Hart, Johnf . Thompson, P. Milos, 2011, Methods in molecular biology.

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Christopher E. Hart, S. Mukhopadhyay, S. Crooke, 2019, Nature Biotechnology.

A modular analysis of microglia gene expression, insights into the aged phenotype

Christopher E. Hart, F. Kamme, C. Cho, 2019, BMC Genomics.

GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells.

Christopher E. Hart, H. Bui, S. Mukhopadhyay, 2023, Molecular therapy. Nucleic acids.

Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks

Christopher E. Hart, B. Wold, E. Mjolsness, 2006, PLoS Comput. Biol..