José Marco-Contelles

发表

Computational Analysis of Aza Analogues of [2', 5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranose]-3'-spiro-5' '- (4' '-amino-1' ', 2' '-oxathiole-2' ', 2' '-dioxide) (TSAO) as HIV-1 Reverse Transcriptase Inhibitors: Relevance of Conformational Properties on the Inhibitory Activity

Elena Soriano, José Marco-Contelles, Cyrille Tomassi, 2006, J. Chem. Inf. Model..

Predicting targets of compounds against neurological diseases using cheminformatic methodology

Lazaros Mavridis, John B. O. Mitchell, Holger Stark, 2015, Journal of Computer-Aided Molecular Design.

Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.

José Marco-Contelles, Antonio Guglietta, R. León, 2006, Journal of medicinal chemistry.

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease.

Li Wang, Alejandro Romero, Isabel Iriepa, 2014, European journal of medicinal chemistry.

Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.

Irene Bolea, F. J. Luque, Jordi Juárez-Jiménez, 2011, Journal of medicinal chemistry.

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

Yagamare Fall, José Marco-Contelles, P. De Deurwaerdère, 2017, ACS chemical neuroscience.

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

Katarina Nikolic, Isabel Iriepa, Elena Soriano, 2014, Drug design, development and therapy.

N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.

Stefano Alcaro, Katarina Nikolic, Francesco Ortuso, 2014, Journal of medicinal chemistry.

Recent advances in the multitarget‐directed ligands approach for the treatment of Alzheimer's disease

José Marco-Contelles, R. León, J. Marco-Contelles, 2013, Medicinal research reviews.

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

Ondřej Soukup, Ewgenij Proschak, Lena Kalinowsky, 2017, Angewandte Chemie.

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

Keith F. Tipton, Irene Bolea, Rona R. Ramsay, 2016, Front. Neurosci..

Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

Xavier Barril, F. J. Luque, F Javier Luque, 2009, Journal of medicinal chemistry.