Cristian G. Bologa

发表

Integration of virtual and physical screening

Dan C. Fara, Tudor I. Oprea, Eric R. Prossnitz, 2006, Drug Discovery Today: Technologies.

Figure 5, Five analogues submitted to support probe SID 88095709 (CID 44640177)

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 15, Overlay of dose response curves for probe ML231 (SID 99300522, CID 3392161)

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 4, Summary of modifications for R2

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 2, Continuation of SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 5, Summary of modifications for R4

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 16, Validated hit and SAR strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 3, SAR summary for modification at R2

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Screening flow chart

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 5, TOR compound triage and flow chart

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Schematic of screen strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Provides New Insights into Integrin Conformation-sensitive Antibody Binding Real-time Analysis of Developmental Biology: Molecular Basis of Cell and

Cristian G. Bologa, Anna Waller, Liliana Halip, 2013 .

Figure 6, Hit scaffold and dose response curves illustrating selectivity for Cdc42

Cristian G. Bologa, Larry A. Sklar, J. Jacob Strouse, 2010 .

Table 3, Summary of modifications for R1

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

High‐Throughput Flow Cytometry

Tudor I. Oprea, Eric R. Prossnitz, Cristian G. Bologa, 2010 .

Figure 9, Focus of SAR expansion efforts based on primary efflux data

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Drug Target Ontology to Classify and Integrate Drug Discovery Data

Rajarshi Guha, Tudor I. Oprea, Cristian G. Bologa, 2017 .

TIN-X: target importance and novelty explorer

Tudor I. Oprea, Cristian G. Bologa, Larry A. Sklar, 2017, Bioinform..

Figure 10, General synthetic scheme for the synthesis of dihydropyrazolines

Cristian G. Bologa, Larry A. Sklar, J. Jacob Strouse, 2010 .

Figure 7, Validated hit resulting from the preliminary commercial SAR effort

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 1, SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 10, TORC1 bypass cell growth analysis on the probe ML231 and SID 96099781

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 2, Summary of modifications to R1

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Mining large chemical spaces in lead and drug discovery

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2006 .

Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Three small molecule pan activator families of Ras-related GTPases

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2010 .

A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7

Cristian G. Bologa, Larry A. Sklar, Chad E. Schroeder, 2013 .

Post-High-Throughput Screening Analysis: An Empirical Compound Prioritization Scheme

Tudor I. Oprea, Eric R. Prossnitz, Cristian G. Bologa, 2005, Journal of biomolecular screening.

Unexplored therapeutic opportunities in the human genome

Anton Simeonov, Christian von Mering, Tudor I. Oprea, 2018, Nature Reviews Drug Discovery.

QSAR for Cycloaliphatic Alcohols with Qualitatively Defined Sandalwood Odour Characteristics

Cristian G. Bologa, Sorel Muresan, Gábor Náray-Szabó, 1999 .

A Potent and Selective Inhibitor of Cdc42 GTPase

Cristian G. Bologa, Larry A. Sklar, Chad E. Schroeder, 2010 .

Unexplored therapeutic opportunities in the human genome

Anton Simeonov, Christian von Mering, Tudor I. Oprea, 2018, Nature Reviews Drug Discovery.

Modulation of Bitter Taste Perception by a Small Molecule hTAS2R Antagonist

Tudor I. Oprea, Cristian G. Bologa, Liliana Ostopovici-Halip, 2010, Current Biology.