David Carling

发表

Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM

George Chennell, Robin J. W. Willows, Sean C. Warren, 2016, Sensors.

Three-dimensional fluorescence imaging by stage-scanning oblique plane microscopy (Conference Presentation)

Paul M. W. French, George Chennell, Sean C. Warren, 2016, SPIE BiOS.

FLIM, FRET and high content analysis

David Carling, Alessandro Sardini, Sunil Kumar, 2020, BiOS.

METABOLIC AND MITOGENIC SIGNAL TRANSDUCTION IN RESPONSE TO INTENSE EXERCISE IN ENDURANCE-TRAINED HUMANS

David Carling, Nigel K. Stepto, Juleen R. Zierath, 2001 .

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

David Carling, Claire Thornton, C. Thornton, 2011, The Biochemical journal.

Structure of Mammalian AMPK and its regulation by ADP

David Carling, Rein Aasland, Steven J. Gamblin, 2011, Nature.

Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation

David Carling, Craig B. Thompson, B. Faubert, 2010, Science.

Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates

George Chennell, David Carling, Alessandro Sardini, 2016, Scientific Reports.

Structural basis of AMPK regulation by small molecule activators

David Carling, Fabrizio Giordanetto, Steven J. Gamblin, 2013, Nature Communications.

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

David Carling, D. Carling, D. Hardie, 1987, FEBS letters.

AMPK, insulin resistance, and the metabolic syndrome.

David Carling, Marc Prentki, M. Prentki, 2013, The Journal of clinical investigation.

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling.

David Carling, Sofianos Andrikopoulos, M. Febbraio, 2006, Cell metabolism.

AMPK signalling in health and disease.

David Carling, D. Carling, 2017, Current opinion in cell biology.

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

Ricardo Lage, David Carling, Antonio Vidal-Puig, 2008, Cell metabolism.

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Janet M. Thornton, David Carling, Linda Partridge, 2009, Science.

Structural basis for AMP binding to mammalian AMP-activated protein kinase

David Carling, Steven J. Gamblin, R. Heath, 2007, Nature.

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Ricardo Lage, David Carling, Matej Orešič, 2010, Nature Medicine.

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Young-Bum Kim, David Carling, D. Carling, 2002, Nature.

Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids.

David Carling, D. Carling, Hilary Clark, 2004, European journal of biochemistry.

The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1

David Carling, D. Hardie, D. Carling, 1999, FEBS letters.

ADP Regulates SNF 1 , the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

David Carling, Steven J. Gamblin, R. Heath, 2011 .

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

David Carling, Seung-Pyo Hong, M. Carlson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The AMP-activated protein kinase cascade--a unifying system for energy control.

David Carling, D. Carling, 2004, Trends in biochemical sciences.

Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

David Carling, Theo Wallimann, Uwe Schlattner, 2003 .

The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways*

David Carling, D. Carling, L. Fryer, 2002, The Journal of Biological Chemistry.

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

David Carling, Steven J. Gamblin, R. Heath, 2011, Cell metabolism.

Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK).

David Carling, Stephen A Baldwin, S. Baldwin, 2002, Journal of cell science.

Thr2446 Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status*

David Carling, D. Carling, L. Fryer, 2004, Journal of Biological Chemistry.