Xavier Deupi

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GPCRmd uncovers the dynamics of the 3D-GPCRome

Toni Giorgino, Davide Provasi, Gianni De Fabritiis, 2020, Nature Methods.

Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome

Toni Giorgino, Davide Provasi, Gianni De Fabritiis, 2020, Nature Methods.

GPCRmd uncovers the dynamics of the 3D-GPCRome

Toni Giorgino, Gianni De Fabritiis, David E. Gloriam, 2019, bioRxiv.

An online resource for GPCR structure determination and analysis

Tilman Flock, Vignir Isberg, Christian Munk, 2019, Nature Methods.

Ser and Thr Residues Modulate the Conformation of Pro-Kinked Transmembrane α-Helices

Leonardo Pardo, Mercedes Campillo, Xavier Deupi, 2004 .

The TXP Motif in the Second Transmembrane Helix of CCR5

Shoshana J. Wodak, Marc Parmentier, Xavier Deupi, 2001, The Journal of Biological Chemistry.

Serine and Threonine Residues Bend α-Helices in the χ1 = g− Conformation

Leonardo Pardo, Eric E. J. Haaksma, Xavier Deupi, 2000 .

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

Xavier Deupi, Gebhard Schertler, D. Oprian, 2011, Proceedings of the National Academy of Sciences.

Conformational complexity of G-protein-coupled receptors.

Xavier Deupi, B. Kobilka, X. Deupí, 2007, Trends in pharmacological sciences.

A Molecular Pharmacologist’s Guide to G Protein–Coupled Receptor Crystallography

Chris de Graaf, Xavier Deupi, C. de Graaf, 2015, Molecular Pharmacology.

Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors

Leonardo Pardo, Tomas Perez-Acle, Xavier Deupi, 2011, PloS one.

GPCR-SAS: A web application for statistical analyses on G protein-coupled receptors sequences

Arnau Cordomí, Marlous Hoogstraat, Mercedes Campillo, 2018, PloS one.

Influence of the g- conformation of Ser and Thr on the structure of transmembrane helices.

Leonardo Pardo, Nicole Dölker, Mercedes Campillo, 2010, Journal of structural biology.

Quantification of structural distortions in the transmembrane helices of GPCRs.

Xavier Deupi, X. Deupí, 2012, Methods in molecular biology.

A Structural Insight into the Reorientation of Transmembrane Domains 3 and 5 during Family A G Protein-Coupled Receptor Activation

Saskia Nijmeijer, Rob Leurs, Leonardo Pardo, 2011, Molecular Pharmacology.

Coupling ligand structure to specific conformational switches in the β2-adrenoceptor

Xavier Deupi, B. Kobilka, X. Deupí, 2006, Nature chemical biology.

Activation of CCR5 by Chemokines Involves an Aromatic Cluster between Transmembrane Helices 2 and 3*

Shoshana J. Wodak, Marc Parmentier, Leonardo Pardo, 2003, The Journal of Biological Chemistry.

Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

Leonardo Pardo, Xavier Deupi, L. Pardo, 2009, The EMBO journal.

Structural insights into agonist-induced activation of G-protein-coupled receptors.

Xavier Deupi, X. Deupí, J. Standfuss, 2011, Current opinion in structural biology.

Structural models of class a G protein-coupled receptors as a tool for drug design: insights on transmembrane bundle plasticity.

Leonardo Pardo, Nicole Dölker, Mercedes Campillo, 2007, Current topics in medicinal chemistry.

Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists*

Xavier Deupi, T. S. Kobilka, Foon Sun Thian, 2005, Journal of Biological Chemistry.

Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

Eric Trinquet, Bernard Pucci, Sébastien Granier, 2012, Proceedings of the National Academy of Sciences.

Probing Gαi1 protein activation at single–amino acid resolution

Tilman Flock, Dawei Sun, M Madan Babu, 2015, Nature Structural &Molecular Biology.

Influence of the environment in the conformation of alpha-helices studied by protein database search and molecular dynamics simulations.

Leonardo Pardo, Xavier Deupi, Mireia Olivella, 2002, Biophysical journal.

The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex

Xavier Deupi, Roger K. Sunahara, Brian T. DeVree, 2009, Proceedings of the National Academy of Sciences.

Activation of G protein-coupled receptors.

Xavier Deupi, B. Kobilka, X. Deupí, 2007, Advances in protein chemistry.

The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein‐Coupled Receptors

Leonardo Pardo, Nicole Dölker, Mercedes Campillo, 2007, Chembiochem : a European journal of chemical biology.