Nicole Kleinstreuer

发表

Identification of Putative Skin Sensitizers Using QSAR Models

A. Tropsha, Vinicius M. Alves, E. Muratov, 2014 .

Development of an Open-Source Integrated Testing Strategy for Skin Sensitization Potency

Nicole Kleinstreuer, Richard W. Morris, Jason R. Pirone, 2014 .

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database*

Bertrand Desprez, Martina Klaric, David Allen, 2018, Critical reviews in toxicology.

Bringing Big Data to Bear in Environmental Public Health: Challenges and Recommendations

Nicole Kleinstreuer, Lucas Joppa, Vasilis Vasiliou, 2020, Frontiers in Artificial Intelligence.

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds.

Alexander Tropsha, Denis Fourches, Nicole Kleinstreuer, 2015, Toxicology and applied pharmacology.

Integrated decision strategies for skin sensitization hazard

David Allen, Nicole Kleinstreuer, Judy Strickland, 2016, Journal of applied toxicology : JAT.

Toward Good Read-Across Practice (GRAP)

Jie Shen, Hao Zhu, Mark T. D. Cronin, 2016 .

Development of a Curated Database of In Vivo Estrogenic Activity

Judy Strickland, Nicole Kleinstreuer, P Ceger, 2014 .

Integrated Testing Strategies (ITS) for safety assessment.

Thomas Hartung, Andreas Schepky, Mardas Daneshian, 2015, ALTEX.

t4 report*: Toward Good Read-Across Practice (GRAP) Guidance

Hao Zhu, Mark T. D. Cronin, Alexandra Maertens, 2016, ALTEX.

Reproducing the ITS-2 model using R

Nicole Kleinstreuer, Richard W. Morris, Judy Strickland, 2014 .

Internationalization of Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology

Thomas Hartung, Manuela Pavan, Francesca Caloni, 2020, ALTEX.

Regulatory acceptance of read-across.

Nicole Kleinstreuer, Thomas Hartung, Thomas Luechtefeld, 2018, ALTEX.

Systems Modeling of Developmental Vascular Toxicity.

Nicole Kleinstreuer, Menghang Xia, Nancy C. Baker, 2019, Current opinion in toxicology.

Abstract 376 — Oral Presentation: Session II-1b "Pathways Approach in Toxicology" Constructing, Quantifying, and Validating an Adverse Outcome Pathway for Vascular Developmental Toxicity

Nicole Kleinstreuer, Warren Casey, Tamara L. Tal, 2014 .

Hierarchical Quantitative Structure-Activity Relationship Modeling Approach for Integrating Binary, Multiclass, and Regression Models of Acute Oral Systemic Toxicity.

Denis Fourches, Nicole Kleinstreuer, Xinhao Li, 2020 .

Application of new approach methodologies: ICE tools to support chemical evaluations

David Allen, Nicole Kleinstreuer, Kamel Mansouri, 2021 .

Usefulness and Applicability of Integrated Strategy Approaches in Toxicology

Silvia Casati, Nicole Kleinstreuer, Janine Ezendam, 2021, Applied In Vitro Toxicology.

Large-Scale Modeling of Multispecies Acute Toxicity End Points Using Consensus of Multitask Deep Learning Methods

Anton Simeonov, Sankalp Jain, Alexey V Zakharov, 2021, J. Chem. Inf. Model..

t4 report: Toward Good Read-Across Practice (GRAP) Guidance

Alexandra Maertens, Nicole Kleinstreuer, Thomas Hartung, 2016, ALTEX.

International regulatory requirements for skin sensitization testing.

Valérie Zuang, João Barroso, Silvia Casati, 2018, Regulatory toxicology and pharmacology : RTP.

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

Ruili Huang, Scott Boyer, Xin Hu, 2020, Environmental health perspectives.

Predicting Skin Sensitization Using 21 st Century Toxicology

Nicole Kleinstreuer, Judy Strickland, Warren Casey, 2014 .

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Ruili Huang, Menghang Xia, David M. Reif, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Predictive models and computational toxicology.

Thomas Knudsen, Nicole Kleinstreuer, Kelly Chandler, 2013, Methods in molecular biology.

Chronic inflammation in the etiology of disease across the life span

Alejandro Lucia, Eric Verdin, Luigi Ferrucci, 2019, Nature Medicine.

Correction to Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model.

Patience Browne, Nicole Kleinstreuer, Richard S Judson, 2017, Environmental science & technology.

Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium

Nicole Kleinstreuer, John P Rooney, J Christopher Corton, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

Alexander Tropsha, Denis Fourches, Nicole Kleinstreuer, 2015, Toxicology and applied pharmacology.

Supporting read-across using biological data.

Nicole Kleinstreuer, Thomas Hartung, Thomas Luechtefeld, 2016, ALTEX.

3S – Systematic, Systemic, and Systems Biology and Toxicology

Raffaella Corvi, Nicole Kleinstreuer, Andre Levchenko, 2019, ALTEX.

Exploring current read-across applications and needs among selected U.S. Federal Agencies.

Patricia Ruiz, Nicole Kleinstreuer, Grace Patlewicz, 2019, Regulatory toxicology and pharmacology : RTP.

Prediction of skin sensitization potency using machine learning approaches

David Allen, Nicole Kleinstreuer, Judy Strickland, 2017, Journal of applied toxicology : JAT.

QSAR models of human data can enrich or replace LLNA testing for human skin sensitization.

Alexander Tropsha, Denis Fourches, Nicole Kleinstreuer, 2016, Green chemistry : an international journal and green chemistry resource : GC.

t 4 report * Supporting Read-Across Using Biological Data

Nicole Kleinstreuer, Thomas Hartung, Thomas Luechtefeld, 2016 .

Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards.

Yu-Mei Tan, Nicole Kleinstreuer, Kristin Isaacs, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies.

David Allen, Nicole Kleinstreuer, Judy Strickland, 2018, Regulatory toxicology and pharmacology : RTP.

Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations

Nicole Kleinstreuer, William H. Bisson, Leroy Lowe, 2016, Environmental health perspectives.

Multivariate models for prediction of human skin sensitization hazard

David Allen, Nicole Kleinstreuer, Judy Strickland, 2017, Journal of applied toxicology : JAT.