Colin Kleanthous

发表

Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

Martin C. J. Maiden, James E. Bray, Connor Sharp, 2017, PLoS Comput. Biol..

The quantitative basis for the redistribution of immobile bacterial lipoproteins to division septa

Seán M. Murray, Colin Kleanthous, Lara Connolley, 2021, PLoS Comput. Biol..

Energy-dependent Immunity Protein Release during tol-dependent Nuclease Colicin Translocation*

Colin Kleanthous, G. Moore, C. Kleanthous, 2009, The Journal of Biological Chemistry.

Following evolutionary paths to protein-protein interactions with high affinity and selectivity

Orly Dym, Dan S. Tawfik, Shlomo Magdassi, 2009, Nature Structural &Molecular Biology.

Ultrahigh specificity in a network of computationally designed protein-interaction pairs

Rosalie Lipsh, Orly Dym, Orli Knop, 2018, Nature Communications.

Nuclease colicins and their immunity proteins

Colin Kleanthous, C. Kleanthous, J. Wojdyla, 2011, Quarterly Reviews of Biophysics.

Conformational Properties of the Unfolded State of Im7 in Nondenaturing Conditions

Sheena E. Radford, Gary S. Thompson, Colin Kleanthous, 2012, Journal of molecular biology.

The Role of Electrostatics in Colicin Nuclease Domain Translocation into Bacterial Cells*

Colin Kleanthous, C. Kleanthous, R. James, 2007, Journal of Biological Chemistry.

Highly discriminating protein-protein interaction specificities in the context of a conserved binding energy hotspot.

Wei Li, Colin Kleanthous, Wei Li, 2004, Journal of molecular biology.

Self‐association of TPR domains: Lessons learned from a designed, consensus‐based TPR oligomer

Anne Marie Krachler, Colin Kleanthous, C. Kleanthous, 2010, Proteins.

High-resolution mass spectrometry of small molecules bound to membrane proteins

Weston B Struwe, Alexander Makarov, Joseph Gault, 2016, Nature Methods.

The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core

Konrad Zdanowski, Shabaz Mohammed, Connor Sharp, 2016, Nature Communications.

Structure of the ultra-high-affinity colicin E2 DNase--Im2 complex.

Justyna Aleksandra Wojdyla, Sarel J Fleishman, Colin Kleanthous, 2012, Journal of molecular biology.

Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

Mark S.P. Sansom, Matthieu Chavent, Jacob Piehler, 2015, Nature.

Protein-protein recognition

Colin Kleanthous, C. Kleanthous, 2000 .

Structures of the Ultra-High-Affinity Protein–Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa

Olwyn Byron, Renata Kaminska, Connor Sharp, 2015, Journal of molecular biology.

Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3

Colin Kleanthous, C. Kleanthous, R. James, 2004, Protein science : a publication of the Protein Society.

Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases.

David Baker, Colin Kleanthous, D. Baker, 2008, Journal of molecular biology.

Intrinsically Disordered Protein Threads Through the Bacterial Outer-Membrane Porin OmpF

Carol V. Robinson, Helen R. Saibil, Renata Kaminska, 2013, Science.

Structure-based Analysis of the Metal-dependent Mechanism of H-N-H Endonucleases*

Colin Kleanthous, C. Kleanthous, M. Maté, 2004, Journal of Biological Chemistry.

Discovery, characterization and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa

Olwyn Byron, Jacqueline M. Matthews, Nicholas P. Tucker, 2016, The Biochemical journal.

Structural and biophysical analysis of nuclease protein antibiotics

Justyna Aleksandra Wojdyla, Olwyn Byron, Renata Kaminska, 2016, The Biochemical journal.

Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate

Sheena E. Radford, Colin Kleanthous, S. Radford, 2001, Nature Structural Biology.

Structural and mechanistic basis of immunity toward endonuclease colicins

Sheena E. Radford, Neil Ferguson, Andrew M. Hemmings, 1999, Nature Structural Biology.

Swimming against the tide: progress and challenges in our understanding of colicin translocation

Colin Kleanthous, C. Kleanthous, 2010, Nature Reviews Microbiology.

Protein-Protein Interaction Specificity of Im9 for the Endonuclease Toxin Colicin E9 Defined by Homologue-scanning Mutagenesis*

Colin Kleanthous, Wei Li, G. Moore, 1997, The Journal of Biological Chemistry.

The effect of protein complexation on the mechanical stability of Im9.

Colin Kleanthous, Sheena E Radford, David J Brockwell, 2007, Biophysical journal.

Im7 folding mechanism: misfolding on a path to the native state

Sheena E. Radford, Colin Kleanthous, S. Radford, 2002, Nature Structural Biology.

Kinetic basis for the competitive recruitment of TolB by the intrinsically disordered translocation domain of colicin E9.

Renata Kaminska, Colin Kleanthous, C. Kleanthous, 2012, Journal of molecular biology.

Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF

Nicholas G. Housden, Colin Kleanthous, C. Kleanthous, 2010, Proceedings of the National Academy of Sciences.

Molecular mimicry enables competitive recruitment by a natively disordered protein.

Colin Kleanthous, C. Kleanthous, E. Dodson, 2007, Journal of the American Chemical Society.

Blind prediction of interfacial water positions in CAPRI

Kengo Kinoshita, Haruki Nakamura, Xiaoqin Zou, 2014, Proteins.

Calorimetric dissection of colicin DNase--immunity protein complex specificity.

Seishi Shimizu, Colin Kleanthous, Anthony H Keeble, 2006, Biochemistry.

Colicin Biology

Colin Kleanthous, S. Buchanan, R. Lloubès, 2007, Microbiology and Molecular Biology Reviews.