Kit I Tong

Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism

Akira Kobayashi, Fumiki Katsuoka, Masayuki Yamamoto, 2006, Biological chemistry.

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Tsutomu Ohta, Koji Tsuta, Hisao Asamura, 2008, Proceedings of the National Academy of Sciences.

Solution structure of the c-terminal core domain of human TFIIB: Similarity to cyclin A and interaction with TATA-binding protein

Danny Reinberg, Mitsuhiko Ikura, Kit I Tong, 1995, Cell.

Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.

Tsutomu Ohta, Masayuki Yamamoto, Shigeyuki Yokoyama, 2006, Molecular cell.

Photo-induced peptide cleavage in the green-to-red conversion of a fluorescent protein.

Atsushi Miyawaki, Hideaki Mizuno, Mitsuhiko Ikura, 2003, Molecular cell.

Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.

Ken Itoh, Masayuki Yamamoto, Kit I Tong, 2004, Free radical biology & medicine.

Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede.

Atsushi Miyawaki, Hideaki Mizuno, Mitsuhiko Ikura, 2007, Journal of molecular biology.

Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.

Ken Itoh, Masayuki Yamamoto, Yasutake Katoh, 2005, Archives of biochemistry and biophysics.