Sheena E Radford

发表

PyXlinkViewer: A flexible tool for visualization of protein chemical crosslinking data within the PyMOL molecular graphics system

Bob Schiffrin, Sheena E Radford, David J Brockwell, 2020, bioRxiv.

Intermediates: ubiquitous species on folding energy landscapes?

Sheena E Radford, David J Brockwell, S. Radford, 2007, Current opinion in structural biology.

N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

Sheena E Radford, J. Baum, A. Ashcroft, 2012, Protein science : a publication of the Protein Society.

An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms

Sheena E Radford, S. Radford, Alice I Bartlett, 2009, Nature Structural &Molecular Biology.

Mechanically unfolding proteins: The effect of unfolding history and the supramolecular scaffold

Sheena E Radford, David J Brockwell, S. Radford, 2002, Protein science : a publication of the Protein Society.

Thermodynamic description of polymorphism in Q- and N-rich peptide aggregates revealed by atomistic simulation.

Sarah A Harris, Sheena E Radford, S. Radford, 2009, Biophysical journal.

Tuning the elastic modulus of hydrated collagen fibrils.

Sheena E Radford, David J Brockwell, S. Radford, 2009, Biophysical journal.

Protein folding: Defining a “standard” set of experimental conditions and a preliminary kinetic data set of two‐state proteins

Kevin W Plaxco, Ingo Ruczinski, Fabrizio Chiti, 2005, Protein science : a publication of the Protein Society.

Amyloid-forming peptides from beta2-microglobulin-Insights into the mechanism of fibril formation in vitro.

Susan Jones, Sheena E Radford, James Manning, 2003, Journal of molecular biology.

Comparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formation

Sheena E Radford, S. Radford, E. Hewitt, 2016, Journal of molecular biology.

From Computer Simulations to Human Disease Emerging Themes in Protein Folding

Christopher M Dobson, Sheena E Radford, C. Dobson, 1999, Cell.

The role of high-dimensional diffusive search, stabilization, and frustration in protein folding.

Emanuele Paci, Sheena E Radford, S. Radford, 2014, Biophysical journal.

Microsecond folding dynamics of the F13W G29A mutant of the B domain of staphylococcal protein A by laser-induced temperature jump.

Sheena E Radford, S. Radford, G. Dimitriadis, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Helix stability and hydrophobicity in the folding mechanism of the bacterial immunity protein Im9.

Sheena E Radford, S. Radford, Claire T. Friel, 2005, Protein engineering, design & selection : PEDS.

The Yin and Yang of protein folding

Sheena E Radford, S. Radford, T. Jahn, 2005, The FEBS journal.

Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP).

Jane Clarke, Benjamin Schuler, Sheena E Radford, 2011, Physical chemistry chemical physics : PCCP.

Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins.

Sheena E Radford, S. Radford, A. Capaldi, 2003, Journal of molecular biology.

Protein folding and binding: from biology to physics and back again.

Michael K Gilson, Sheena E Radford, S. Radford, 2011, Current opinion in structural biology.

The effect of protein complexation on the mechanical stability of Im9.

Colin Kleanthous, Sheena E Radford, David J Brockwell, 2007, Biophysical journal.

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate

M. J. Parker, Sheena E Radford, S. Radford, 2006, Nature Structural &Molecular Biology.

The role of conformational flexibility in β2-microglobulin amyloid fibril formation at neutral pH

Sheena E Radford, S. Radford, A. Ashcroft, 2012, Rapid communications in mass spectrometry : RCM.

The effect of increasing the stability of non-native interactions on the folding landscape of the bacterial immunity protein Im9.

Emanuele Paci, Sheena E Radford, S. Radford, 2007, Journal of molecular biology.

Mechanically unfolding the small, topologically simple protein L.

Emanuele Paci, Sheena E Radford, David J Brockwell, 2005, Biophysical journal.

Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules

Richard Turner, Nikil Kapur, Sheena E Radford, 2018, Biotechnology and bioengineering.

Pulling geometry defines the mechanical resistance of a β-sheet protein

Emanuele Paci, Sheena E Radford, David J Brockwell, 2003, Nature Structural Biology.

Switching two-state to three-state kinetics in the helical protein Im9 via the optimisation of stabilising non-native interactions by design.

Sheena E Radford, S. Radford, G. Beddard, 2004, Journal of molecular biology.

Conformational dynamics is more important than helical propensity for the folding of the all α‐helical protein Im7

Sheena E Radford, S. Radford, Stuart E. Knowling, 2013, Protein science : a publication of the Protein Society.

The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism

Robert G Griffin, Galia T Debelouchina, Matthew G Iadanza, 2018, Nature Communications.

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

Collin M. Stultz, Collin M Stultz, Barbara Imperiali, 2010, Proceedings of the National Academy of Sciences.

Pulling geometry defines the mechanical resistance of a beta-sheet protein.

Emanuele Paci, Sheena E Radford, David J Brockwell, 2003, Nature structural biology.