Adolfo García-Sastre

发表

Attacking the flu: New prospects for the rational design of antivirals

Estanislao Nistal-Villán, Adolfo García-Sastre, A. García-Sastre, 2009, Nature Medicine.

Moving from Empirical to Rational Vaccine Design in the ‘Omics’ Era

Shashank Tripathi, Adolfo García-Sastre, Mansi Sharma, 2019, Vaccines.

Discovery of SARS-CoV-2 Antivirals through Large-scale Drug Repositioning

Eytan Ruppin, Andrew I Su, Ren Sun, 2020, Nature.

Antiviral Response in Pandemic Influenza Viruses

Adolfo García-Sastre, A. García-Sastre, 2006, Emerging infectious diseases.

Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1

Rong Wang, Adolfo García-Sastre, A. García-Sastre, 2005, PLoS pathogens.

Influenza A virus transmission bottlenecks are defined by infection route and recipient host.

Marshall Crumiller, Adolfo García-Sastre, Nicole M. Bouvier, 2014, Cell host & microbe.

Influenza Research Database: an integrated bioinformatics resource for influenza research and surveillance

Richard H Scheuermann, Catherine Macken, Sam Zaremba, 2012, Influenza and other respiratory viruses.

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Paul Shinn, Wei Zheng, Jennifer Kouznetsova, 2014, Emerging Microbes & Infections.

Programming the magnitude and persistence of antibody responses with innate immunity

John Steel, Robert J. Hogan, Rajesh Ravindran, 2010, Nature.

Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.

Estanislao Nistal-Villán, Adolfo García-Sastre, A. García-Sastre, 2007, Molecular cell.

Viral tricks to grid-lock the type I interferon system

Adolfo García-Sastre, A. García-Sastre, Gijs A Versteeg, 2010, Current Opinion in Microbiology.

Transcription Elongation Can Affect Genome 3D Structure

Max W. Chang, Lars Pache, Adolfo García-Sastre, 2018, Cell.

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

David E. Swayne, Adolfo García-Sastre, Jeffery K. Taubenberger, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

Bali Pulendran, Adolfo García-Sastre, Balaji Manicassamy, 2010, Proceedings of the National Academy of Sciences.

Origins of the 2009 H1N1 influenza pandemic in swine in Mexico

Andrew Rambaut, Martha I Nelson, Adolfo García-Sastre, 2016, eLife.

Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection

Hui Zeng, Andrea J. Sant, Adolfo García-Sastre, 2016, Journal of Virology.

MHC class II proteins mediate cross-species entry of bat influenza viruses

Martin Beer, Anne Halenius, Max W. Chang, 2019, Nature.

Overcoming NS1-mediated immune antagonism involves both interferon-dependent and independent mechanisms.

Juilee Thakar, Steven H Kleinstein, Adolfo García-Sastre, 2013, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses

Steven H. Kleinstein, Stuart C. Sealfon, Maria Chikina, 2015, Journal of Virology.

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Jacques Fellay, Agatha Schlüter, Aurora Pujol, 2020, Science.

An Unconventional NLS is Critical for the Nuclear Import of the Influenza A Virus Nucleoprotein and Ribonucleoprotein

Adolfo García-Sastre, A. García-Sastre, P. Palese, 2005, Traffic.

Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases.

Christopher Y. Park, Olga G Troyanskaya, Dmitriy Gorenshteyn, 2015, Immunity.

H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice

John J. Treanor, Karolina Palucka, Adolfo García-Sastre, 2013, Journal of Virology.

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Andrew R. Leach, Anna Gaulton, Aurelien Dugourd, 2020, Cell.

Predicting the pathogenesis of influenza from genomic response: a step toward early diagnosis

Adolfo García-Sastre, A. García-Sastre, E. Bortz, 2011, Genome Medicine.

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

David E. Swayne, Michael G. Katze, Adolfo García-Sastre, 2006, Nature.

Virulence determinants of pandemic influenza viruses.

Adolfo García-Sastre, A. García-Sastre, Donna M. Tscherne, 2011, The Journal of clinical investigation.

The intracellular sites of early replication and budding of SARS-coronavirus

Silke Stertz, Adolfo García-Sastre, G. Kochs, 2007, Virology.

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

Jian Jin, Xiaoting Chen, Miriam Merad, 2016, Science.

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

Adolfo García-Sastre, Florian Krammer, Jens Wrammert, 2012, Proceedings of the National Academy of Sciences.

Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding

John Steel, Jianqiang Ye, Marion Koopmans, 2010, Journal of Virology.

Induction and evasion of type I interferon responses by influenza viruses.

Adolfo García-Sastre, A. García-Sastre, 2011, Virus research.

Pause on Avian Flu Transmission Research

John Steel, Paul G. Thomas, Yi Guan, 2012, Science.

Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian Species

John Steel, Adolfo García-Sastre, Balaji Manicassamy, 2011, PLoS pathogens.

Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation.

Zhenghong Yuan, Adolfo García-Sastre, M. Habjan, 2009, The Journal of general virology.

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

John Steel, Adolfo García-Sastre, A. García-Sastre, 2010, mBio.

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling.

Adolfo García-Sastre, M. J. Evans, A. García-Sastre, 2016, Cell host & microbe.

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility

Adolfo García-Sastre, Florian Krammer, Nicole M. Bouvier, 2013, Nature Communications.

The guinea pig as a transmission model for human influenza viruses.

Adolfo García-Sastre, Samira Mubareka, A. García-Sastre, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches.

Jonas Grossmann, Sacha Baginsky, Martin Schwemmle, 2007, Journal of proteome research.

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.

Adolfo García-Sastre, A. García-Sastre, Gijs A Versteeg, 2013, Immunity.

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing.

Shou-Wei Ding, Adolfo García-Sastre, Kyle L. Johnson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.

Paul Shinn, Shihua He, Wei Zheng, 2018, Journal of medicinal chemistry.

Human interactome of the influenza B virus NS1 protein

Richard E. Randall, Catherine H. Botting, Adolfo García-Sastre, 2017, The Journal of general virology.

Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

Adolfo García-Sastre, A. García-Sastre, P. Rottier, 2011, PLoS pathogens.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Trey Ideker, Claudia Hernandez-Armenta, Brian K. Shoichet, 2020, bioRxiv.

Inhibition of interferon signaling by dengue virus

Adolfo García-Sastre, J. Muñoz-Jordán, A. García-Sastre, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Introductions and early spread of SARS-CoV-2 in the New York City area

Gintaras Deikus, Marta Luksza, Andrew Kasarskis, 2020, Science.

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

Carl W Davis, Christopher Chiu, Adolfo García-Sastre, 2014, Proceedings of the National Academy of Sciences.

Influenza Virus Sequence Feature Variant Type Analysis: Evidence of a Role for NS1 in Influenza Virus Host Range Restriction

Brett E. Pickett, Richard H. Scheuermann, Monnie McGee, 2012, Journal of Virology.

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

Irene Ramos, Adolfo García-Sastre, Rong Hai, 2011, PLoS pathogens.

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

Carole R. Baskin, Michael G. Katze, Adolfo García-Sastre, 2009, Proceedings of the National Academy of Sciences.

Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine.

Adolfo García-Sastre, R. Webby, A. Vincent, 2007, Vaccine.