Craig Rosenstein

Scheme 1, Synthesis of ML260

Jiwen Zou, Santhi Ganji, Ian Pass, 2013 .

Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders.

Jongwon Lim, Michael D Altman, Craig Rosenstein, 2011, Journal of medicinal chemistry.

Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.

Wei Lu, Michael D Altman, Craig Rosenstein, 2013, Journal of medicinal chemistry.

Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms.

Thomas Rush, Andrew M Haidle, Michael D Altman, 2014, Bioorganic & medicinal chemistry letters.

The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: lead optimization.

Tony Siu, Michael D Altman, Lin Xu, 2014, Bioorganic & medicinal chemistry letters.