Angel Guzman-Perez

Exploring Aromatic Chemical Space with NEAT: Novel and Electronically Equivalent Aromatic Template

Brajesh K. Rai, Alan M. Mathiowetz, Meihua Tu, 2012, J. Chem. Inf. Model..

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity.

Li Xing, Leonard Buckbinder, Amy Baumann, 2009, Bioorganic & medicinal chemistry letters.

Defining the key pharmacophore elements of PF-04620110: discovery of a potent, orally-active, neutral DGAT-1 inhibitor.

Angel Guzman-Perez, Dawn Mather, W. Zavadoski, 2013, Bioorganic & medicinal chemistry.

Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors.

Steve Schneider, Xin Huang, Angel Guzman-Perez, 2013, ACS medicinal chemistry letters.

Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.

Steve Schneider, Xin Huang, John Newcomb, 2013, Journal of medicinal chemistry.

Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylase.

Eliot Sugarman, Zhengrong Zhao, Wei Song, 2012, Journal of medicinal chemistry.

Corrigendum to “Defining the key pharmacophore elements of PF-04620110: Discovery of a potent, orally-active, neutral DGAT-1 inhibitor” [Bioorg. Med. Chem. 21 (2013) 5081–5097]

Robert L. Dow, Angel Guzman-Perez, Jian-Cheng Li, 2013 .

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.

Roman Shimanovich, Angel Guzman-Perez, R. Fremeau, 2017, Journal of medicinal chemistry.

Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1.

Eliot Sugarman, Angel Guzman-Perez, G. S. Walker, 2011, ACS medicinal chemistry letters.

Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation.

Leonard Buckbinder, Jacquelyn Klug-McLeod, Angel Guzman-Perez, 2008, Bioorganic & medicinal chemistry letters.