Nicole Soranzo

发表

MultiMeta: an R package for meta-analyzing multi-phenotype genome-wide association studies

Dragana Vuckovic, Paolo Gasparini, Nicole Soranzo, 2015, Bioinform..

GARFIELD - GWAS Analysis of Regulatory or Functional Information Enrichment with LD correction

Ewan Birney, Klaudia Walter, Nicole Soranzo, 2016, bioRxiv.

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

Mark I. McCarthy, Philippe Froguel, Paul Elliott, 2011, Nature Genetics.

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Giovanni Malerba, Jin Li, Rohit Varma, 2017, Nature Genetics.

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Tom R. Gaunt, Klaudia Walter, Nicholas J Timpson, 2015, Nature Communications.

Whole-genome sequencing of patients with rare diseases in a national health system

Keith W. Muir, William J. Astle, Mark I. McCarthy, 2020, Nature.

Genomic atlas of the human plasma proteome

Stephen Burgess, David Stacey, Bram P. Prins, 2018, Nature.

An associated interval approach for identifying candidate causal variants underlying altered activity of the ABCB1 multi-drug resistance gene.

Nicole Soranzo, Nicholas W. Wood, D Goldstein, 2003 .

An interactive genome browser of association results from the UK10K cohorts project

Jie Huang, Klaudia Walter, Tim J. P. Hubbard, 2015, Bioinform..

Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits

Berthold Göttgens, Nicole Soranzo, Suthesh Sivapalaratnam, 2011, PLoS genetics.

Differential methylation of the TRPA1 promoter in pain sensitivity

Chrysanthi Ainali, Frank O. Nestle, Sophia Tsoka, 2014, Nature Communications.

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Thomas Meitinger, Inês Barroso, Peter Kraft, 2010, Nature Genetics.

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

Nicole Soranzo, Panos Deloukas, Fumihiko Takeuchi, 2009, PLoS genetics.

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits

Nicole Soranzo, Eric E. Schadt, Serge Ferrari, 2010, PLoS genetics.

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

Gail Clement, Jie Huang, Antonio Ciampi, 2014, Nature Communications.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Christian Gieger, Thomas Meitinger, Inês Barroso, 2009, Nature Genetics.

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Inês Barroso, Jiyoung Heo, Beverley Balkau, 2015, Nature communications.

Edinburgh Research Explorer Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution

Laura J. Scott, Christian Gieger, Yurii S. Aulchenko, 2022 .

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

Christian Gieger, Ming-Huei Chen, Luigi Ferrucci, 2009, Nature Genetics.

Multiple Loci Are Associated with White Blood Cell Phenotypes

Christian Gieger, Yusuke Nakamura, Kazuhiko Yamamoto, 2011, PLoS genetics.

Consequences of natural perturbations in the human plasma proteome

Stephen Burgess, David Stacey, Bram P. Prins, 2017, bioRxiv.

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

Jie Huang, Inês Barroso, Tom R. Gaunt, 2017, American journal of human genetics.

The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits

Christian Gieger, Lon R. Cardon, Kourosh R. Ahmadi, 2011, PloS one.

Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies

Yurii S. Aulchenko, Nicole Soranzo, Panagiotis Deloukas, 2009, Nature Genetics.

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

Henning Gall, Andrea Olschewski, Horst Olschewski, 2018, Nature Communications.

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Thomas Meitinger, Inês Barroso, Peter Kraft, 2011, Nature Genetics.

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

Alfonso Valencia, Nicole Soranzo, Daniel Rico, 2016, bioRxiv.

New gene functions in megakaryopoiesis and platelet formation

Christian Gieger, Yusuke Nakamura, Ian J. Deary, 2011, Nature.

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

Sylvia Stracke, Christian Gieger, Joshua C. Denny, 2015, Diabetes.

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE Consortium

Ming-Huei Chen, Qiong Yang, Nicole Soranzo, 2010 .

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

John P. A. Ioannidis, Nicole Soranzo, Panagiotis Deloukas, 2009 .

A brief history of human disease genetics

Mark I. McCarthy, Heidi L. Rehm, Jay Shendure, 2020, Nature.

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control.

Nicole Soranzo, Manuel A. R. Ferreira, Sarah E Medland, 2010, American journal of human genetics.

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

Ming-Huei Chen, Qiong Yang, Nicole Soranzo, 2010, Circulation.

Genome-wide association study identifies five loci associated with lung function

Inês Barroso, Philippe Froguel, Eva Schnabel, 2010, Nature Genetics.

Functional interpretation of non-coding sequence variation: Concepts and challenges

Nicole Soranzo, Stephan Beck, Dirk S Paul, 2013, BioEssays : news and reviews in molecular, cellular and developmental biology.

Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk

Christian Gieger, Xiaofeng Zhu, Paolo Vineis, 2011, Nature.

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

Laura J. Scott, Christian Gieger, Yurii S. Aulchenko, 2009, PLoS Genetics.

Erratum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes (Nature Genetics (2011) 43 (561-564))

Mark I. McCarthy, Kourosh R. Ahmadi, Nicole Soranzo, 2011 .

Transcriptional diversity during lineage commitment of human blood progenitors

Randy J. Read, William J. Astle, Paul Flicek, 2014, Science.

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Christian Gieger, Sanghoon Moon, Tien Yin Wong, 2017, PLoS Medicine.

Directional dominance on stature and cognition in diverse human populations

Laura J. Scott, Claude Bouchard, Christian Gieger, 2015, Nature.

A single-nucleotide polymorphism tagging set for human drug metabolism and transport

Nicole Soranzo, Nicholas W Wood, David B Goldstein, 2005, Nature Genetics.

Seventy-five genetic loci influencing the human red blood cell

Christian Gieger, Ian J. Deary, Uwe Völker, 2012, Nature.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Christian Gieger, Alex Doney, Inês Barroso, 2010, Nature Genetics.

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Christian Gieger, Uwe Völker, Mario Falchi, 2009, Nature Genetics.

Edinburgh Research Explorer Common variants at 10 genomic loci influence hemoglobin A(C) levels via glycemic and nonglycemic pathways

Christian Gieger, Nicole Soranzo, Josée Dupuis, 2010 .

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Christian Gieger, Inês Barroso, Meena Kumari, 2011, Nature Genetics.

Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Gail Clement, Jie Huang, Inês Barroso, 2016, Nature Communications.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Christian Gieger, Jianxin Shi, Inês Barroso, 2013, Nature Genetics.

A genome-wide association study identifies three loci associated with mean platelet volume.

Christian Gieger, Thomas Meitinger, Henry Völzke, 2009, American journal of human genetics.

A reference panel of 64,976 haplotypes for genotype imputation

Laura J. Scott, He Zhang, Gonçalo Abecasis, 2015, bioRxiv.

Identification of an imprinted master trans-regulator at the KLF14 locus related to multiple metabolic phenotypes

Mark I. McCarthy, Kourosh R. Ahmadi, Nicole Soranzo, 2011, Nature Genetics.

Edinburgh Explorer Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

Beth Wilmot, Joel Eriksson, Jie Huang, 2022 .

Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults

Christian Gieger, Ian J. Deary, Jie Huang, 2011, Circulation.

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Jie Huang, William J. Astle, Bengt Sennblad, 2016, Nature Genetics.

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

He Zhang, Andres Metspalu, Fotios Drenos, 2016, Nature Genetics.

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Christian Gieger, Jingyuan Fu, Thomas Meitinger, 2011, Nature Genetics.

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

Paul Flicek, Nicole Soranzo, Simon Heath, 2016, Nature Communications.

A genome-wide perspective of genetic variation in human metabolism

Christian Gieger, Thomas Meitinger, Florian Kronenberg, 2010, Nature Genetics.

Whole-genome sequence-based analysis of thyroid function

Jie Huang, Tom R. Gaunt, Klaudia Walter, 2015, Nature communications.

Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach

Christian Gieger, Nicole Soranzo, Gabi Kastenmüller, 2013, Diabetes.

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Subhajyoti De, Inês Barroso, Philippe Froguel, 2008, Nature Genetics.

The impact of rare and low-frequency genetic variants in common disease

Klaudia Walter, Nicole Soranzo, Lorenzo Bomba, 2017, Genome Biology.

Variants in MTNR1B influence fasting glucose levels

Inês Barroso, Paul Scheet, Nicole Soranzo, 2009, Nature Genetics.

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Claude Bouchard, William Wheeler, Peter Kraft, 2014 .

IRF4 variants have age-specific effects on nevus count and predispose to melanoma.

Nicole Soranzo, Johan Hansson, Nicholas G Martin, 2010, American journal of human genetics.

Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

Christian Gieger, Nicole Soranzo, Simone Wahl, 2014, Genome Medicine.

Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size

Inês Barroso, Kourosh R. Ahmadi, Nicole Soranzo, 2009, PLoS genetics.

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Christian Gieger, Inês Barroso, Peter Kraft, 2010, Nature Genetics.