Paul M Ridker

发表

Efficient Bayesian mixed model analysis increases association power in large cohorts

Bonnie Berger, George Tucker, Po-Ru Loh, 2014 .

Advances in Measuring the Effect of Individual Predictors of Cardiovascular Risk: The Role of Reclassification Measures

Nancy R Cook, Paul M Ridker, N. Cook, 2009, Annals of Internal Medicine.

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events.

Nancy R Cook, Nader Rifai, Paul M Ridker, 2002, The New England journal of medicine.

A guiding map for inflammation

Richard Hotchkiss, Michael T Heneka, Alberto Mantovani, 2017, Nature Immunology.

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Thomas Meitinger, Inês Barroso, Peter Kraft, 2010, Nature Genetics.

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.

Peter Kraft, Joshua C Denny, Uwe Völker, 2016, Gastroenterology.

Alcohol Consumption and Plasma Concentration of C-Reactive Protein

Robert J Glynn, Paul M Ridker, Michelle A Albert, 2003, Circulation.

Genome-Wide Association Study Evaluating Lipoprotein-Associated Phospholipase A2 Mass and Activity at Baseline and After Rosuvastatin Therapy

Fredrik Nyberg, Josée Dupuis, Harald Grallert, 2012, Circulation. Cardiovascular genetics.

High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention.

Paul M Ridker, P. Ridker, 2003, The American journal of cardiology.

Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) Study Design

Harlan M Krumholz, John A Spertus, Paul M Ridker, 2010, Circulation. Cardiovascular quality and outcomes.

Evaluation of the Pooled Cohort Risk Equations for Cardiovascular Risk Prediction in a Multiethnic Cohort From the Women’s Health Initiative

Samia Mora, Jennifer G. Robinson, JoAnn E. Manson, 2018, JAMA internal medicine.

Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

Hongyu Wu, Donna K Arnett, Millennia Foy, 2015, The American journal of clinical nutrition.

Association between a literature-based genetic risk score and cardiovascular events in women.

Nancy R Cook, Nina P Paynter, Guillaume Paré, 2010, JAMA.

The Present and FutureReview Topic of the WeekA Test in Context: High-Sensitivity C-Reactive Protein

Paul M Ridker, P. Ridker, 2016 .

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Inês Barroso, Jiyoung Heo, Beverley Balkau, 2015, Nature communications.

Pleiotropic genes for metabolic syndrome and inflammation.

Eric Boerwinkle, Josée Dupuis, Sharon L R Kardia, 2014, Molecular genetics and metabolism.

Comparing Cardiovascular Risk Prediction Scores

Nancy R Cook, Paul M Ridker, N. Cook, 2015, Annals of Internal Medicine.

Novel genetic markers improve measures of atrial fibrillation risk prediction

Nancy R. Cook, Daniel I. Chasman, Paul M Ridker, 2013, European heart journal.

High sensitivity C-reactive protein in clinical practice.

Paul M Ridker, P. Ridker, José L Torres, 2003, The American heart hospital journal.

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

Børge G Nordestgaard, Robert J Glynn, Paul M Ridker, 2009, The Lancet.

Natriuretic Peptide Precursor A Gene Polymorphisms and Risk of Blood Pressure Progression and Incident Hypertension

Robert J Glynn, Paul M Ridker, P. Ridker, 2007, Hypertension.

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Thomas Meitinger, Inês Barroso, Peter Kraft, 2011, Nature Genetics.

Physical Activity and Reduced Risk of Cardiovascular Events: Potential Mediating Mechanisms

Samia Mora, I-Min Lee, Nancy Cook, 2007, Circulation.

C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients.

Paul M Ridker, P. Ridker, J. Willerson, 2006, Journal of the American College of Cardiology.

Prediction of incident hypertension risk in women with currently normal blood pressure.

Nancy R Cook, Nina P Paynter, Paul M Ridker, 2009, The American journal of medicine.

Cardiovascular Disease Risk Prediction With and Without Knowledge of Genetic Variation at Chromosome 9p21.3

Nancy R Cook, Nina P Paynter, Daniel I Chasman, 2009, Annals of Internal Medicine.

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

Antonio Colombo, Chun Yuan, Morteza Naghavi, 2003, Circulation.

Edinburgh Research Explorer Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies

Jean-François Dartigues, Reinhold Schmidt, Sudha Seshadri, 2022 .

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

Jie Huang, Uwe Völker, Ming-Huei Chen, 2017, PloS one.

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Hynek Pikhart, Fernando Pires Hartwig, Joshua C Denny, 2017, The lancet. Diabetes & endocrinology.

Fasting Compared With Nonfasting Lipids and Apolipoproteins for Predicting Incident Cardiovascular Events

Samia Mora, Nader Rifai, Paul M Ridker, 2008, Circulation.

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.

Peter Kraft, Eric Boerwinkle, Josée Dupuis, 2010, Human molecular genetics.

Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authorities

Paul M Ridker, Wolfgang Koenig, P. Ridker, 2010, European heart journal.

Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk

Christian Gieger, Xiaofeng Zhu, Paolo Vineis, 2011, Nature.

Blood Pressure, C-Reactive Protein, and Risk of Future Cardiovascular Events

Nader Rifai, Paul M Ridker, P. Ridker, 2003, Circulation.

Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk.

Nader Rifai, David F Dinges, Paul M Ridker, 2004, Journal of the American College of Cardiology.

Performance of commercial platforms for rapid genotyping of polymorphisms affecting warfarin dose.

Paul M Ridker, P. Ridker, B. Gage, 2008, American journal of clinical pathology.

Personalized cardiovascular disease prevention by applying individualized prediction of treatment effects.

Frank L J Visseren, Paul M Ridker, P. Ridker, 2014, European heart journal.

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Christian Gieger, Sanghoon Moon, Tien Yin Wong, 2017, PLoS Medicine.

Reported outcomes in major cardiovascular clinical trials funded by for-profit and not-for-profit organizations: 2000-2005.

Paul M Ridker, P. Ridker, José L Torres, 2006, JAMA.

Comparison of the Framingham and Reynolds Risk Scores for Global Cardiovascular Risk Prediction in the Multiethnic Women's Health Initiative

Jennifer G. Robinson, Nancy R Cook, Nina P Paynter, 2012, Circulation.

Inflammation, C-reactive protein, and atherothrombosis.

Paul M Ridker, P. Ridker, J. Silvertown, 2008, The Journal of Periodontology.

Population analysis of large copy number variants and hotspots of human genetic disease.

Richard M Myers, Deborah A Nickerson, Jun Li, 2009, American journal of human genetics.

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open angle glaucoma

Robert N Weinreb, Peter Kraft, Terry Gaasterland, 2015, Nature Genetics.

Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults

Claude Bouchard, Christian Gieger, Tuija Tammelin, 2017 .

Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy

Munir Pirmohamed, Robert J Glynn, Stephen E Kimmel, 2011, Thrombosis and Haemostasis.

C-Reactive Protein: A Simple Test to Help Predict Risk of Heart Attack and Stroke

Paul M Ridker, P. Ridker, 2003, Circulation.

Genetic Testing for Cardiovascular Disease Susceptibility: A Useful Clinical Management Tool or Possible Misinformation?

Philippa J Talmud, Paul M Ridker, P. Ridker, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Mendelian Randomization Causal Analysis Using Genetics to Test the Causal Relationship of Total Adiposity and Periodontitis: Mendelian Randomization Analyses in the Gene-lifestyle Interactions and Dental Endpoints (glide) Consortium

Peter Kraft, Alexander Teumer, Tom M Palmer, 2022 .

New loci associated with kidney function and chronic kidney disease

Uwe Völker, Luigi Ferrucci, Reinhold Schmidt, 2010, Nature Genetics.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Christian Gieger, Gonçalo Abecasis, He Gao, 2018, Nature Genetics.

A trial-based approach to statin guidelines.

Paul M Ridker, P. Ridker, P. Wilson, 2013, JAMA.

Complete blood count risk score and its components, including RDW, are associated with mortality in the JUPITER trial

Nina P Paynter, Paul M Ridker, N. Paynter, 2015, European journal of preventive cardiology.

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Fernando Pires Hartwig, Claude Bouchard, Christian Gieger, 2018, American journal of human genetics.

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

Claude Bouchard, Uwe Völker, Todd L Edwards, 2016, Nature Genetics.

Residual inflammatory risk: addressing the obverse side of the atherosclerosis prevention coin.

Paul M Ridker, P. Ridker, 2016, European heart journal.

Anti-inflammatory therapies for cardiovascular disease.

Paul M Ridker, P. Ridker, T. Lüscher, 2014, European heart journal.

Cardiovascular event reduction and adverse events among subjects attaining low-density lipoprotein cholesterol <50 mg/dl with rosuvastatin. The JUPITER trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin).

Paul M Ridker, P. Ridker, J. Hsia, 2011, Journal of the American College of Cardiology.

Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial.

Nader Rifai, Christopher P Cannon, David A Morrow, 2005, Journal of the American College of Cardiology.

Genome-wide association study reveals three susceptibility loci for common migraine in the general population

Wolfgang Hoffmann, Henry Völzke, Boukje de Vries, 2011, Nature Genetics.

Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?

Paul M Ridker, P. Ridker, P. Wilson, 2004, Circulation.

Estimating treatment effects for individual patients based on the results of randomised clinical trials

Ewout W Steyerberg, Nancy R Cook, Nina P Paynter, 2011, BMJ : British Medical Journal.

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Christian Gieger, Gonçalo Abecasis, He Gao, 2017, bioRxiv.

Blood pressure and risk of developing type 2 diabetes mellitus: the Women's Health Study.

Samia Mora, Robert J Glynn, Paul M Ridker, 2007, European heart journal.

Use of aspirin as primary prevention of cardiovascular events.

Nancy R Cook, Paul M Ridker, Julie E Buring, 2006, JAMA.

Gamma-glutamyl carboxylase and its influence on warfarin dose

Elena Deych, Petra Lenzini, Paul M Ridker, 2010, Thrombosis and Haemostasis.

Inactivating mutations in NPC1L1 and protection from coronary heart disease.

John Spertus, Thomas Meitinger, Joshua C Denny, 2014, The New England journal of medicine.

Statins: new American guidelines for prevention of cardiovascular disease

Nancy R Cook, Paul M Ridker, N. Cook, 2013, The Lancet.

C-Reactive Protein, the Metabolic Syndrome, and Risk of Incident Cardiovascular Events: An 8-Year Follow-Up of 14 719 Initially Healthy American Women

Nancy R Cook, Nader Rifai, Paul M Ridker, 2003, Circulation.

Inflammation in atherosclerosis: from pathophysiology to practice.

Paul M Ridker, Peter Libby, P. Libby, 2009, Journal of the American College of Cardiology.

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Christian Gieger, Jingyuan Fu, Thomas Meitinger, 2011, Nature Genetics.

Rosuvastatin for Primary Prevention in Older Persons With Elevated C-Reactive Protein and Low to Average Low-Density Lipoprotein Cholesterol Levels: Exploratory Analysis of a Randomized Trial

Robert J. Glynn, Børge G. Nordestgaard, Paul M Ridker, 2010, Annals of Internal Medicine.

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.

Sylvia Stracke, Christian Gieger, Alex Doney, 2012, Human molecular genetics.

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

Olle Melander, Nathan O Stitziel, Sekar Kathiresan, 2015, The Lancet.

Interpretation of Mendelian randomization studies and the search for causal pathways in atherothrombosis: the need for caution.

Nina P Paynter, Robert J Glynn, Paul M Ridker, 2010, Metabolic syndrome and related disorders.

Lipoprotein Particle Profiles by Nuclear Magnetic Resonance Compared With Standard Lipids and Apolipoproteins in Predicting Incident Cardiovascular Disease in Women

Samia Mora, Nader Rifai, Paul M Ridker, 2009, Circulation.

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Xiaofeng Zhu, Vladan Mijatovic, Inês Barroso, 2016, Nature Genetics.

Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women.

Paul M Ridker, Kathryn M Rexrode, J. Manson, 2007, Clinical chemistry.

Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.

Luigi Ferrucci, Degui Zhi, Weihua Guan, 2016, The American journal of clinical nutrition.

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Claude Bouchard, Christian Gieger, Joel Eriksson, 2016, Nature communications.

Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy.

Daniel I Chasman, Paul M Ridker, P. Ridker, 2009, Atherosclerosis.

Common genetic variations in the vitamin D pathway in relation to blood pressure.

Daniel I Chasman, Paul M Ridker, Audrey Y. Chu, 2014, American journal of hypertension.

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

Hynek Pikhart, Bengt Sennblad, Tom R. Gaunt, 2015, The Lancet.

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.

Uwe Völker, Tim Kacprowski, Ming-Huei Chen, 2015, Blood.

The Effect of Including C-Reactive Protein in Cardiovascular Risk Prediction Models for Women

Nancy R Cook, Paul M Ridker, N. Cook, 2006, Annals of Internal Medicine.

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

Xiaofeng Zhu, Todd L Edwards, Wei Guo, 2013, American journal of human genetics.

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

Mark Woodward, Yoav Ben-Shlomo, Johan Sundström, 2012 .

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Joshua C Denny, Wei-Qi Wei, Fredrik Nyberg, 2016, Journal of Medical Genetics.

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Christian Gieger, Inês Barroso, Peter Kraft, 2010, Nature Genetics.