Peter D Kwong

发表

CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline

Gwo-Yu Chuang, Reda Rawi, Chen-Hsiang Shen, 2018, J. Chem. Inf. Model..

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

Lynn Morris, Chaim A. Schramm, John R Mascola, 2015, Nature Medicine.

Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

Gwo-Yu Chuang, Wei Shi, Ivelin S Georgiev, 2014, The Journal of Immunology.

Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.

Christoph Grundner, Wayne A Hendrickson, Marie Pancera, 2003, Virology.

Crystal structure , conformational fixation , and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016 .

Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield.

Cinque S. Soto, Jonathan Stuckey, Peter D Kwong, 2017, Structure.

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120.

Wayne A Hendrickson, Peter D Kwong, Joseph Sodroski, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

Young Do Kwon, Asim K Debnath, Peter D Kwong, 2017, Journal of medicinal chemistry.

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.

Scott D Boyd, Lynn Morris, Ivelin S Georgiev, 2014, Cell host & microbe.

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Baoshan Zhang, Edward M Marcotte, Cornelia L Dekker, 2016, Nature Medicine.

Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.

François Stricher, Wayne A Hendrickson, Peter D Kwong, 2005, Structure.

HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth

Carole A Bewley, Priyamvada Acharya, Peter D Kwong, 2015, Expert opinion on therapeutic targets.

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.

Young Do Kwon, Joel R Courter, Peter D Kwong, 2011, Bioorganic & medicinal chemistry.

Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies.

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2013, Immunity.

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

Lynn Morris, Gwo-Yu Chuang, David C Montefiori, 2017, PLoS pathogens.

Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains.

Peter D Kwong, Joseph Sodroski, E. Rosenberg, 2003, Virology.

Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity.

Young Do Kwon, Hongtao Zhang, Asim K Debnath, 2015, Journal of medicinal chemistry.

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Tongqing Zhou, Baoshan Zhang, Sam Darko, 2016, Immunity.

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

Baoshan Zhang, Wayne C Koff, Carole A Bewley, 2013, Nature Structural &Molecular Biology.

HIV vaccine design and the neutralizing antibody problem

Wayne C Koff, Ian A Wilson, Dennis R Burton, 2004, Nature Immunology.

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

Tongqing Zhou, Hongmei Gao, David C Montefiori, 2018, PLoS pathogens.

De novo identification of VRC01 class HIV-1–neutralizing antibodies by next-generation sequencing of B-cell transcripts

Tongqing Zhou, Baoshan Zhang, James C Mullikin, 2013, Proceedings of the National Academy of Sciences.

Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.

Guido Ferrari, Jaranit Kaewkungwal, Xiaozhi Lu, 2013, Immunity.

Interfacial metal and antibody recognition.

Tongqing Zhou, Wayne A Hendrickson, Peter D Kwong, 2005, Proceedings of the National Academy of Sciences of the United States of America.