Xia Chen

Defensive Resource Allocation: The Roles of Forecast Information and Risk Control

Yucheng Dong, Jun Zhuang, Xia Chen, 2020, Risk analysis : an official publication of the Society for Risk Analysis.

Fiber on a chip: nonlinear optics for data communication via silicon photonic wires

Richard M. Osgood, Yurii A. Vlasov, Nicolae C. Panoiu, 2008 .

Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.

William Greenlee, Lynn Hyde, Xia Chen, 2012, Journal of medicinal chemistry.

Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validation.

Lingyan Wang, Andrew Stamford, Michael Czarniecki, 2010, Journal of medicinal chemistry.

Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease.

Qin Jiang, William J Greenlee, Xia Chen, 2016, Journal of medicinal chemistry.

Discovery of potent iminoheterocycle BACE1 inhibitors.

Brian McKittrick, Andrew Stamford, Xia Chen, 2014, Bioorganic & medicinal chemistry letters.

The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer’s disease patients

Michael Tanen, Matthew E. Kennedy, Wei Li, 2016, Science Translational Medicine.

Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.

Andrew Stamford, William Greenlee, Guoqing Li, 2010, Bioorganic & medicinal chemistry letters.

Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction.

Suresh Babu, William J Greenlee, Xia Chen, 2012, ACS medicinal chemistry letters.