Alexander G. Fletcher

发表

Ten Simple Rules for a Successful Cross-Disciplinary Collaboration

Alexander G. Fletcher, Charlotte M. Deane, David Gavaghan, 2015, PLoS Comput. Biol..

Numerical Analysis of the Immersed Boundary Method for Cell-Based Simulation

Fergus R. Cooper, Ruth E. Baker, Alexander G. Fletcher, 2016, bioRxiv.

MultiCellDS: a community-developed standard for curating microenvironment-dependent multicellular data

Alexander G. Fletcher, Roeland M. H. Merks, Jacob G. Scott, 2016, bioRxiv.

Chaste: An Open Source C++ Library for Computational Physiology and Biology

Alexander G. Fletcher, David Gavaghan, Yohan Davit, 2013, PLoS Comput. Biol..

Faculty Opinions recommendation of Comparing different ODE modelling approaches for gene regulatory networks.

Alexander G. Fletcher, Philip K. Maini, 2009 .

Robust cell tracking in epithelial tissues through identification of maximum common subgraphs

Ruth E. Baker, Alexander G. Fletcher, Rémi Bardenet, 2016, bioRxiv.

Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

Alexander G. Fletcher, Alexander R. A. Anderson, Jacob G. Scott, 2015, bioRxiv.

A parallel implementation of an off-lattice individual-based model of multicellular populations

Alexander G. Fletcher, James M. Osborne, Joe Pitt-Francis, 2015, Comput. Phys. Commun..

Comparing Individual-Based Approaches to Modelling the Self-Organization of Multicellular Tissues

Alexander G. Fletcher, David J. Gavaghan, James M. Osborne, 2016 .

Impact of implementation choices on quantitative predictions of cell-based computational models

Ruth E. Baker, Alexander G. Fletcher, Jochen Kursawe, 2017, bioRxiv.

A hierarchical Bayesian framework for understanding the spatiotemporal dynamics of the intestinal epithelium

Alexander G. Fletcher, Helen M. Byrne, Philip K. Maini, 2016, bioRxiv.

MultiCellDS: a standard and a community for sharing multicellular data

Alexander G. Fletcher, Roeland M. H. Merks, Jacob G. Scott, 2016, bioRxiv.

Capabilities and Limitations of Tissue Size Control through Passive Mechanical Forces

Ruth E. Baker, Alexander G. Fletcher, Pavel A. Brodskiy, 2015, bioRxiv.

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

Alexander G. Fletcher, Peter Jeavons, Robert A. Gatenby, 2015, PLoS Comput. Biol..

Multiscale modelling of intestinal crypt organization and carcinogenesis

Alexander G. Fletcher, Philip K. Maini, Philip J. Murray, 2015, 1506.05019.

A Computational Modelling Approach for Deriving Biomarkers to Predict Cancer Risk in Premalignant Disease

Alexander G. Fletcher, Andrew Dhawan, Trevor A. Graham, 2015, bioRxiv.

Impact of implementation choices on quantitative predictions of cell-based computational models

Ruth E. Baker, Alexander G. Fletcher, Jochen Kursawe, 2017, J. Comput. Phys..

Novel Methods for Analysing Bacterial Tracks Reveal Persistence in Rhodobacter sphaeroides

Ruth E. Baker, Alexander G. Fletcher, Judith P. Armitage, 2013, PLoS Comput. Biol..

QuickStitch for seamless stitching of confocal mosaics through high-pass filtering and recursive normalization

Alexander G. Fletcher, Pavel A. Brodskiy, Jeremiah J. Zartman, 2016, bioRxiv.

Chaste: A test-driven approach to software development for biological modelling

Alexander G. Fletcher, David Gavaghan, Pras Pathmanathan, 2009, Comput. Phys. Commun..

Chaste: An Open Source C plus plus Library for Computational Physiology and Biology

Alexander G. Fletcher, Yohan Davit, Gary R. Mirams, 2013 .

Toward Engineering Biosystems With Emergent Collective Functions

Alexander G. Fletcher, Thomas E. Gorochowski, Sabine Hauert, 2020, Frontiers in Bioengineering and Biotechnology.

Comparing individual-based approaches to modelling the self-organization of multicellular tissues

Alexander G. Fletcher, David Gavaghan, James M. Osborne, 2016, bioRxiv.

Approximate Bayesian computation reveals the importance of repeated measurements for parameterising cell-based models of growing tissues

Ruth E. Baker, Alexander G. Fletcher, Jochen Kursawe, 2017, bioRxiv.

Ten Simple Rules for Effective Computational Research

Alexander G. Fletcher, Charlotte M. Deane, David Gavaghan, 2014, PLoS Comput. Biol..

A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium

Alexander G. Fletcher, Helen M. Byrne, Philip K. Maini, 2017, PLoS Comput. Biol..

Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots

Alexander G. Fletcher, Richard A. Blythe, Jochen Kursawe, 2020, Physical biology.

Seven challenges in the multiscale modeling of multicellular tissues

Alexander G. Fletcher, James M. Osborne, 2021 .

Oxygen consumption dynamics in steady-state tumour models

Alexander G. Fletcher, David Robert Grimes, Mike Partridge, 2014, Royal Society Open Science.

An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells

Alexander G. Fletcher, Lucia Marucci, Elisa Pedone, 2017, npj Systems Biology and Applications.

Towards patient-specific biology-driven heterogeneous radiation planning: using a computational model of tumor growth to identify novel radiation sensitivity signatures.

Alexander G. Fletcher, David Basanta, Alexander R. A. Anderson, 2014 .

Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi

Alexander G. Fletcher, Helen M. Byrne, Philip K. Maini, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Multiscale modeling of colonic crypts and early colorectal cancer

Alexander G. Fletcher, Kwang-Hyun Cho, Helen M. Byrne, 2010 .

Mechanocellular models of epithelial morphogenesis

Fergus R. Cooper, Ruth E. Baker, Alexander G. Fletcher, 2017, Philosophical Transactions of the Royal Society B: Biological Sciences.

Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon

Alexander G. Fletcher, Paul J. Tadrous, Nicholas A. Wright, 2014, Cell reports.

Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences

Alexander G. Fletcher, Alexander Bucksch, Christophe Pradal, 2017, bioRxiv.

A PHABULOSA/Cytokinin Feedback Loop Controls Root Growth in Arabidopsis

Alexander G. Fletcher, Philip K. Maini, Ben Scheres, 2012, Current Biology.