Sean R. Donohue

发表

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Masahiro Fujita, Robert B. Innis, Victor W. Pike, 2014, NeuroImage.

Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type‐1 receptors in vivo

Sean R. Donohue, B. Gulyás, C. Halldin, 2009, Synapse.

Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.

Sean R. Donohue, B. Gulyás, C. Halldin, 2008, Journal of medicinal chemistry.

Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.

Victor W. Pike, Christer Halldin, Amy K. Chesterfield, 2008, Journal of medicinal chemistry.

Imaging and Quantitation of Cannabinoid CB 1 Receptors in Human and Monkey Brains

Jeih-San Liow, Cheryl L. Morse, Robert B. Innis, 2010 .

Imaging and Quantitation of Cannabinoid CB1 Receptors in Human and Monkey Brains Using 18F-Labeled Inverse Agonist Radioligands

Jeih-San Liow, Cheryl L. Morse, Robert B. Innis, 2010, Journal of Nuclear Medicine.

In vitro and in vivo evaluation of 11 CSD 5024 , a novel PET radioligand for human brain imaging of cannabinoid CB 1 receptors ☆ O F

Sean R. Donohue, Kimberly J. Jenko, C. Halldin, 2013 .

Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.

Sean R. Donohue, B. Gulyás, C. Halldin, 2009, Bioorganic & medicinal chemistry letters.

A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates

Sean R. Donohue, B. Gulyás, S. Hjorth, 2016, Neuropharmacology.

In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse

Sean R. Donohue, B. Gulyás, T. Freund, 2013, Brain Research Bulletin.

[125I]SD-7015 reveals fine modalities of CB1 cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease

Sean R. Donohue, B. Gulyás, M. Palkovits, 2012, Neurochemistry International.

Synthesis and Evaluation of Two 18F-Labeled 6-Iodo-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine Derivatives as Prospective Radioligands for β-Amyloid in Alzheimer’s Disease

Sean R. Donohue, S. Zoghbi, J. Liow, 2004 .

DEVELOPMENT OF CANNABINOID SUBTYPE-1 (CB1) RECEPTOR LIGANDS FOR PET

Sean R. Donohue, 2008 .

N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.

Sean R. Donohue, C. Halldin, V. Pike, 2011, Journal of medicinal chemistry.

Radiolabeling of a high potency cannabinoid subtype‐1 receptor ligand, N‐(4‐fluoro‐benzyl)‐4‐(3‐(piperidin‐1‐yl)‐indole‐1‐sulfonyl)benzamide (PipISB), with carbon‐11 or fluorine‐18

Sean R. Donohue, S. Hitchcock, C. Halldin, 2008 .

Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging.

Sean R. Donohue, C. Halldin, V. Pike, 2006, Bioorganic & medicinal chemistry.

A facile and regioselective synthesis of rimonabant through an enamine-directed 1,3-dipolar cycloaddition

Sean R. Donohue, C. Halldin, V. Pike, 2008 .

A concise and efficient synthesis of flumazenil and its precursor for radiolabeling with fluorine-18

Sean R. Donohue, R. Dannals, 2009 .

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Sean R. Donohue, Kimberly J. Jenko, C. Halldin, 2014, NeuroImage.