Nigel J. Titchener-Hooker

发表

Changing manufacturing paradigms in downstream processing and the role of alternative bioseparation technologies

Richard Tran, Karol Lacki, Andrew Davidson, 2014 .

Separation of Fab Fragments from Realistic Feedstocks Using Mixed Mode Chromatography.

Nigel J. Titchener-Hooker, Daniel G. Bracewell, Pj Beckett, 2008 .

Feasibility measure studies on chromatographic purification of antibody fragment from clarified lysate

Nigel J. Titchener-Hooker, Hk Kim, Jmp King, 2006 .

An experimental determination of the particle density distribution of streamline expanded bed adsorbents

Sally Hassan, Nigel J. Titchener-Hooker, Nicholas Willoughby, 2005 .

The use of scale-down approaches to enable rapid investigation and characterization of the initial downstream process for antibody fragment production in E.coli.

Nigel J. Titchener-Hooker, Ad Tustian, Lc Bowering, 2007 .

Mimicking interfacial effects in bioprocessing of monoclonal antibodies

Nigel J. Titchener-Hooker, Daniel G. Bracewell, James G. Biddlecombe, 2006 .

An engineering study of key interactions within the process for antibody fragment production

Nigel J. Titchener-Hooker, Mike Hoare, Ad Tustian, 2008 .

Evaluation of a structural mechanics model to predict the effect of inserts in the bed support of chromatographic columns

Nigel J. Titchener-Hooker, Spyridon Gerontas, Tian Lan, 2013 .

High throughput screening of particle conditioning operations: II. Evaluation of scale‐up heuristics with prokaryotically expressed polysaccharide vaccines

Nigel J. Titchener-Hooker, Aaron Noyes, Ranga Godavarti, 2015, Biotechnology and bioengineering.

A modular approach for the ultra-scale-down of depth filtration

Richard S. Wright, Jim Mullin, Nigel J. Titchener-Hooker, 2015 .

Report and recommendation of a workshop on education and training for measurement, monitoring, modelling and control (M3C) in biochemical engineering

Krist V. Gernaey, Carl-Fredrik Mandenius, Volker C. Hass, 2010, Biotechnology journal.

Global Sensitivity Analysis for the determination of parameter importance in Protein A chromatography

Nigel J. Titchener-Hooker, Richard Francis, Eli Keshavarz-Moore, 2006 .

Back to the future – the use of batch adsorption in the recovery of antibody fragments from an E. coli disruptates

Nigel J. Titchener-Hooker, Daniel G. Bracewell, Mike Hoare, 2008 .

Effect of membrane pleating upon filter membrane cartridge performance

Nigel J. Titchener-Hooker, Gary J. Lye, A. I. Brown, 2008 .

Scale-Down as a Tool for Process Synthesis in hte Initial Stages of Protein Recovery from Transgenic Milk

Nigel J. Titchener-Hooker, Lars W. Pampel, M Udell, 1999 .

Accelerated physicochemical characterization of complex protein mixtures for optimised chromatographic separation.

Nigel J. Titchener-Hooker, Daniel G. Bracewell, Alex Berrill, 2007 .

BIOT 299-Accelerated physico-chemical characterization of complex protein mixtures for optimized ion-exchange chromatographic separation

Nigel J. Titchener-Hooker, Daniel G. Bracewell, Alex Berrill, 2007 .

Speeding the translation from laboratory to production

Nigel J. Titchener-Hooker, Jl Novais, Nj Murrell, 2000 .

Holistic bioprocess development and control.

Nigel J. Titchener-Hooker, H Baldascini, Daniel G. Bracewell, 2005 .

THE EFFECT OF FLUID-JET MIXING ON PROTEIN PRECIPITATE GROWTH DURING LOW-FREQUENCY CONDITIONING

Nigel J. Titchener-Hooker, Mike Hoare, M. Hoare, 1992 .

Prediction of drop breakage in an ultra high velocity jet homogenizer

Nigel J. Titchener-Hooker, N. Titchener-Hooker, P. Shamlou, 2001 .

Experimental verification and optimisation of a detailed dynamic high performance liquid chromatography column model

Eva Sorensen, Nigel J. Titchener-Hooker, H. K. Teoh, 2001 .

Quantification and prediction of jet macro-mixing times in static microwell plates

Nigel J. Titchener-Hooker, Gary J. Lye, Ronan D. O'Kennedy, 2006 .

Modelling and simulation of fractional precipitation : comparison with pilot plant data

Nigel J. Titchener-Hooker, A. I. Clarkson, I.D.L. Bogle, 1992 .

Experimental verification and optimisation of a detailed dynamic high performance liquid chromatographic column model

Eva Sorensen, Nigel J. Titchener-Hooker, Nigel J. Titchener-Hooker, 2000 .

Effect of fouling on the capacity and breakthrough characteristics of a packed bed ion exchange chromatography column

Nigel J. Titchener-Hooker, Mike Hoare, M. Hoare, 2006, Bioprocess and biosystems engineering.

Confocal imaging of chromatographic fouling under flow conditions

Nigel J. Titchener-Hooker, Rihab Boushaba, Rolf Hjorth, 2007 .

Influence of shear on particle size and fractal dimension of whey protein precipitates: implications for scale-up and centrifugal clarification efficiency

Edmond P. Byrne, Nigel J. Titchener-Hooker, John J. Fitzpatrick, 2002 .

The effects of material properties and fluid flow intensity on plasmid DNA recovery during cell lysis

Nigel J. Titchener-Hooker, P. Ayazi Shamlou, Peter Dunnill, 1999 .

A physical model of high-pressure disruption of bakers' yeast cells

Nigel J. Titchener-Hooker, P. Ayazi Shamlou, N. Titchener-Hooker, 1995 .

A systematic approach for modeling chromatographic processes—Application to protein purification

Eva Sorensen, Nigel J. Titchener-Hooker, Daniel G. Bracewell, 2008 .

Studies on membrane sterile filtration of plasmid DNA using an automated multiwell technique

Nigel J. Titchener-Hooker, Simyee Kong, N. Titchener-Hooker, 2010 .

Evaluation of a pH-stat feeding strategy on the production and recovery of Fab’ fragments from E. coli

Nigel J. Titchener-Hooker, Frank Baganz, Ian Buchanan, 2005 .