Sarah L. Williams

发表

Self-Evaluation Maintenance Model

Anne E. Wilson, Sarah L. Williams, 2017 .

Active RB elicits late G1/S inhibition.

Steven P. Angus, Sarah L. Williams, H. F. Horn, 2002, Experimental cell research.

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Sarah L. Williams, F. Supek, M. Barrett, 2020, Nature Microbiology.

Changes in DNA bending and flexing due to tethered cations detected by fluorescence resonance energy transfer

Lawrence J. Parkhurst, Laura K Parkhurst, Sarah L. Williams, 2006, Nucleic acids research.

TraY and Integration Host Factor oriT Binding Sites and F Conjugal Transfer: Sequence Variations, but Not Altered Spacing, Are Tolerated

Sarah L. Williams, J. Schildbach, 2007, Journal of bacteriology.

Subdomain organization and catalytic residues of the F factor TraI relaxase domain.

Dana L. Miller, Sarah L. Williams, J. Schildbach, 2003, Biochimica et biophysica acta.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Dual Allosteric Inhibition of SHP2 Phosphatase.

Sarah L. Williams, S. Blacklow, M. Glick, 2018, ACS chemical biology.

Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.

Sarah L. Williams, Robert Koenig, Mitsunori Kato, 2019, Journal of medicinal chemistry.

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.

Sarah L. Williams, D. Bussiere, X. Ling, 2021, Journal of medicinal chemistry.

Examination of an inverted repeat within the F factor origin of transfer: context dependence of F TraI relaxase DNA specificity

Sarah L. Williams, J. Schildbach, 2006, Nucleic acids research.

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.

Sarah L. Williams, W. Sellers, Z. Deng, 2020, Journal of medicinal chemistry.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ping Zhu, Gang Liu, Peter Fekkes, 2016, Nature.

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.

Sarah L. Williams, D. Bussiere, Sylvia Ma, 2020, Journal of medicinal chemistry.

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.

Sarah L. Williams, Robert Koenig, Mitsunori Kato, 2019, Journal of medicinal chemistry.

High-Throughput Melanin-Binding Affinity and In Silico Methods to Aid in the Prediction of Drug Exposure in Ocular Tissue.

Sarah L. Williams, M. Serrano-Wu, J. Reilly, 2015, Journal of pharmaceutical sciences.

Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action.

Matthew W. Strobeck, Steven P. Angus, Sarah L. Williams, 2002, Cancer research.

Study of the Conformational Dynamics of the Catalytic Loop of WT and G140A/G149A HIV-1 Integrase Core Domain Using Reversible Digitally Filtered Molecular Dynamics.

Jonathan W Essex, Sarah L. Williams, J. Essex, 2009, Journal of chemical theory and computation.

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Sarah L. Williams, F. Supek, M. Barrett, 2019, bioRxiv.

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Sarah L. Williams, M. Barrett, J. Mottram, 2020, Nature Microbiology.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.