Sandra K. Wittmann

发表

PENG: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation, and Virtual Screening for Novel Ligands of LTA4H

Daniel Moser, Jan Kramer, Janosch Achenbach, 2015, J. Chem. Inf. Model..

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Gerd Geisslinger, Ewgenij Proschak, Daniel Merk, 2017, Journal of medicinal chemistry.

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

Sandra K. Wittmann, G. Scriba, O. Werz, 2017, Scientific Reports.

Soluble epoxide hydrolase inhibitors with carboranes as non-natural 3-D pharmacophores.

Sandra K. Wittmann, E. Proschak, Matthias S. Scholz, 2019, European journal of medicinal chemistry.

The mTOR Inhibitor Everolimus Induces Proteinuria and Renal Deterioration in the Remnant Kidney Model in the Rat

Sandra K. Wittmann, C. Daniel, A. Braun, 2007, Transplantation.

Long-Term Treatment of Sirolimus but Not Cyclosporine Ameliorates Diabetic Nephropathy in the Rat

Sandra K. Wittmann, C. Daniel, K. Amann, 2009, Transplantation.

Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat.

Sandra K. Wittmann, C. Daniel, R. Voll, 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.

Sandra K. Wittmann, D. Steinhilber, S. George, 2020, Journal of medicinal chemistry.

Design and synthesis of fused soluble epoxide hydrolase/peroxisome proliferator-activated receptor modulators

Sandra K. Wittmann, D. Steinhilber, M. Schubert-Zsilavecz, 2016 .

Thermodynamic properties of leukotriene A4 hydrolase inhibitors.

Sandra K. Wittmann, S. Knapp, D. Steinhilber, 2016, Bioorganic & medicinal chemistry.

A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity.

Sandra K. Wittmann, J. Lausen, E. Proschak, 2018, Analytical biochemistry.

The mTOR Inhibitor Everolimus Attenuates the Time Course of Chronic Anti-Thy1 Nephritis in the Rat

Sandra K. Wittmann, H. Kawachi, C. Daniel, 2008, Nephron Experimental Nephrology.

Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase.

Sandra K. Wittmann, O. Werz, D. Steinhilber, 2019, ACS medicinal chemistry letters.

Computer-Aided Selective Optimization of Side Activities of Talinolol.

Sandra K. Wittmann, D. Steinhilber, Daniel Moser, 2019, ACS medicinal chemistry letters.

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase

Sandra K. Wittmann, D. Steinhilber, E. Proschak, 2016, Molecules.

PDE-5 inhibition impedes TSP-1 expression, TGF-beta activation and matrix accumulation in experimental glomerulonephritis.

Sandra K. Wittmann, C. Daniel, B. Hohenstein, 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators.

Sandra K. Wittmann, D. Steinhilber, B. Brüne, 2016, Journal of medicinal chemistry.

Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases.

Sandra K. Wittmann, D. Steinhilber, Franca-Maria Klingler, 2017, ACS infectious diseases.

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

Sandra K. Wittmann, J. Lausen, E. Proschak, 2014, Nature Communications.

Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.

Sandra K. Wittmann, D. Steinhilber, R. Marschalek, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

Sandra K. Wittmann, D. Steinhilber, M. Schubert-Zsilavecz, 2019, Front. Pharmacol..

Synthesis and Structure − Activity Relationship Studies of Novel Dual Inhibitors of Soluble Epoxide Hydrolase and 5 ‐ Lipoxygenase

Ste, Sandra K. Wittmann, D. Steinhilber, 2013 .

Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain.

Sandra K. Wittmann, S. Knapp, D. Steinhilber, 2018, Journal of medicinal chemistry.

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

Ste, Sandra K. Wittmann, S. Knapp, 2019 .

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

Sandra K. Wittmann, G. Scriba, O. Werz, 2017, Scientific Reports.

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

Sandra K. Wittmann, J. Lausen, E. Proschak, 2014, Nature Communications.

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Sandra K. Wittmann, D. Steinhilber, M. Wurglics, 2017, Journal of medicinal chemistry.

Bacterial Expression and HTS Assessment of Soluble Epoxide Hydrolase Phosphatase

Sandra K. Wittmann, Franca-Maria Klingler, E. Proschak, 2016, Journal of biomolecular screening.