Colleen E. Keohane

发表

A new class of synthetic retinoid antibiotics effective against bacterial persisters

Huajian Gao, Petia M. Vlahovska, Michael S. Gilmore, 2018, Nature.

Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase.

Colleen E. Keohane, J. Karanicolas, W. Wuest, 2020, ACS infectious diseases.

Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity.

Colleen E. Keohane, W. Wuest, Andrew D. Steele, 2016, Journal of the American Chemical Society.

Transcriptomic Profiling Suggests That Promysalin Alters the Metabolic Flux, Motility, and Iron Regulation in Pseudomonas putida KT2440.

Colleen E. Keohane, S. Sieber, M. Filiatrault, 2018, ACS infectious diseases.

N-Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia.

Colleen E. Keohane, J. Edwards, E. Jacoby, 2022, Journal of medicinal chemistry.

Total synthesis and biological investigation of (-)-promysalin.

Colleen E. Keohane, W. Wuest, Andrew D. Steele, 2015, Journal of the American Chemical Society.

Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection

Colleen E. Keohane, F. Ausubel, E. Mylonakis, 2023, Antimicrobial agents and chemotherapy.

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Colleen E. Keohane, J. Karanicolas, S. Sieber, 2018, Journal of the American Chemical Society.

The Rhizosphere Microbiome: A Playground for Natural Product Chemists

Colleen E. Keohane, W. Wuest, Andrew D. Steele, 2015, Synlett.

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Colleen E. Keohane, J. Karanicolas, S. Sieber, 2018, Journal of the American Chemical Society.