Obinna C Ubah

发表

Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability.

John Steven, Obinna C Ubah, Magdalena J Buschhaus, 2018, Biochemical Society transactions.

Monoclonal Antibodies and Antibody Like Fragments Derived from Immunised Phage Display Libraries

Obinna C Ubah, Soumya Palliyil, S. Palliyil, 2018, Advances in experimental medicine and biology.

An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

Obinna C Ubah, C. Barelle, A. Porter, 2019, Front. Immunol..

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Obinna C Ubah, C. Barelle, J. Steven, 2017, Front. Immunol..

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

Obinna C Ubah, Kathryn L. Pepple, R. V. Van Gelder, 2019, Translational vision science & technology.

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

Obinna C Ubah, A. LeBeau, Eric W. Lake, 2021, Nature Communications.

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties.

Obinna C Ubah, Magdalena J Buschhaus, C. Barelle, 2020, Methods in molecular biology.

Enhancing the transdermal delivery of ‘next generation’ variable new antigen receptors using microarray patch technology: a proof-of-concept study

Obinna C Ubah, C. Barelle, R. Donnelly, 2022, Journal of Pharmaceutical Sciences.

Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic Development.

Obinna C Ubah, C. Barelle, Marina Kovaleva, 2022, Methods in molecular biology.

In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug Development

Obinna C Ubah, C. Barelle, A. Porter, 2020, Journal of immunology research.

Cancer therapy: Targeting mitochondria and other sub-cellular organelles.

Obinna C Ubah, H. Wallace, Obinna C. Ubah, 2014, Current pharmaceutical design.

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Obinna C Ubah, C. Barelle, A. Porter, 2017, Front. Immunol..