Benjamin D. Sellers

发表

Physics-based refinement of proteins in model systems

Benjamin D. Sellers, 2008 .

chemalot and chemalot_knime: Command line programs as workflow tools for drug discovery

Bernd Wiswedel, Benjamin D. Sellers, Man-Ling Lee, 2017, Journal of Cheminformatics.

Conformation switching of clathrin light chain regulates clathrin lattice assembly.

Benjamin D. Sellers, R. Fletterick, M. Jacobson, 2010, Developmental cell.

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors

Vijay S. Pande, Benjamin D. Sellers, Anton V. Sinitskiy, 2016, Scientific Reports.

Improving the species cross-reactivity of an antibody using computational design.

Benjamin D. Sellers, Benjamin D Sellers, Matthew P Jacobson, 2009, Bioorganic & medicinal chemistry letters.

Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors.

Benjamin D. Sellers, Rohan V Mendonca, Sanjeev Kumar, 2020, ACS medicinal chemistry letters.

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

Benjamin D. Sellers, K. Scearce-Levie, M. Volgraf, 2016, Journal of medicinal chemistry.

Structure of the essential inner membrane lipopolysaccharide–PbgA complex

Benjamin D. Sellers, M. Hunter, D. DePonte, 2020, Nature.

A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain

Benjamin D. Sellers, Brandon M. Brown, M. Volgraf, 2017, Neuropharmacology.

Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.

Benjamin D. Sellers, Jun Liang, C. Koth, 2022, Journal of medicinal chemistry.

Towards an Improved Understanding of Drug Excipient Interactions to Enable Rapid Optimization of Nanosuspension Formulations.

Benjamin D. Sellers, Dennis H. Leung, J. Ferrar, 2020, International journal of pharmaceutics.

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

Benjamin D. Sellers, Qiang Zhou, M. Volgraf, 2016, Neuron.

Toward better refinement of comparative models: Predicting loops in inexact environments

Kai Zhu, Richard A Friesner, Benjamin D. Sellers, 2008, Proteins.

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Benjamin D. Sellers, Jun Liang, Y. Franke, 2018, Nature.

Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).

Benjamin D. Sellers, Rohan V Mendonca, G. Hatzivassiliou, 2018, ACS medicinal chemistry letters.

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models

Benjamin D. Sellers, J. Elstrott, K. Scearce-Levie, 2020, Cell reports.

Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity.

Benjamin D. Sellers, D. Sutherlin, D. Hackos, 2018, Journal of medicinal chemistry.

Effects of somatic mutations on CDR loop flexibility during affinity maturation

Benjamin D. Sellers, Matthew P Jacobson, Sergio E Wong, 2011, Proteins.

Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA

Benjamin D. Sellers, Cécile Chalouni, C. Koth, 2018, Antimicrobial Agents and Chemotherapy.

Energy-based analysis and prediction of the orientation between light- and heavy-chain antibody variable domains.

Benjamin D. Sellers, Benjamin D Sellers, Matthew P Jacobson, 2009, Journal of molecular biology.

A Comparison of Quantum and Molecular Mechanical Methods to Estimate Strain Energy in Druglike Fragments

Benjamin D. Sellers, Benjamin D Sellers, Natalie C James, 2017, J. Chem. Inf. Model..

GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile.

Benjamin D. Sellers, K. Scearce-Levie, M. Volgraf, 2017, ACS medicinal chemistry letters.

Comparison of logP and logD correction models trained with public and proprietary data sets

Benjamin D. Sellers, I. Aliagas, A. Gobbi, 2022, Journal of Computer-Aided Molecular Design.

Antibodies as a model system for comparative model refinement

Benjamin D. Sellers, Benjamin D Sellers, Matthew P Jacobson, 2010, Proteins.

Incorporating NOE-Derived Distances in Conformer Generation of Cyclic Peptides with Distance Geometry

Benjamin D. Sellers, Anastasia C. Murthy, N. Popovych, 2022, J. Chem. Inf. Model..

Improving the species cross-reactivity of an antibody using computational design.

Benjamin D. Sellers, C. Craik, M. Jacobson, 2009, Bioorganic & medicinal chemistry letters.