Richard N Upton

ADVAN-style analytical solutions for common pharmacokinetic models.

Ahmad Y Abuhelwa, David J R Foster, Richard N Upton, 2015, Journal of pharmacological and toxicological methods.

Altering blood flow does not reveal differences between nitrogen and helium kinetics in brain or in skeletal miracle in sheep.

David J Doolette, Richard N Upton, R. Upton, 2015, Journal of applied physiology.

Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs – method development and application to magnesium in sheep

Richard N Upton, R. Upton, G. Ludbrook, 2005, BMC pharmacology.

A quantitative alternative to the hysteresis plot for measurement of drug transit time.

David J Doolette, Richard N Upton, R. Upton, 2002, Journal of pharmacological and toxicological methods.

A Physiologically Based, Recirculatory Model of the Kinetics and Dynamics of Propofol in Man

Richard N Upton, Guy Ludbrook, R. Upton, 2005, Anesthesiology.

Perfusion–diffusion compartmental models describe cerebral helium kinetics at high and low cerebral blood flows in sheep

David J Doolette, Richard N Upton, R. Upton, 2005, The Journal of physiology.

Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models.

Lars Arendt-Nielsen, Richard N Upton, Asbjørn M Drewes, 2011, Basic & clinical pharmacology & toxicology.

CEREBRAL UPTAKE OF DRUGS IN HUMANS

Richard N Upton, R. Upton, 2007, Clinical and experimental pharmacology & physiology.