Mingyue Zheng

发表

Computational methods for drug design and discovery: focus on China

Cheng Luo, Hualiang Jiang, Honglin Li, 2013, Trends in Pharmacological Sciences.

Estimation of elimination half-lives of organic chemicals in humans using gradient boosting machine.

Xiaomin Luo, Xiaochen Zhang, Jing Lu, 2016, Biochimica et biophysica acta.

Analysis and prediction of drug–drug interaction by minimum redundancy maximum relevance and incremental feature selection

Lai Wei, Lei Chen, Tao Huang, 2017, Journal of biomolecular structure & dynamics.

KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules

Xiaomin Luo, Mingyue Zheng, Kaixian Chen, 2019, Bioinform..

Machine Learning-Based Modeling of Drug Toxicity.

Xiaomin Luo, Jing Lu, Mingyue Zheng, 2018, Methods in molecular biology.

A Genetic Algorithm Based Support Vector Machine Model for Blood-Brain Barrier Penetration Prediction

Xiaomin Luo, Mingyue Zheng, Kaixian Chen, 2015, BioMed research international.

DrugSpaceX: a large screenable and synthetically tractable database extending drug space

Mingyue Zheng, Zhaojun Li, Zunyun Fu, 2020, Nucleic Acids Res..

A hybrid framework for improving uncertainty quantification in deep learning-based QSAR regression modeling

Mingyue Zheng, Dingyan Wang, Xutong Li, 2021, Journal of Cheminformatics.

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

Hao Jiang, Cheng Luo, Zhifeng Chen, 2017, Organic & biomolecular chemistry.

Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

Cheng Luo, Mingyue Zheng, Zhongjie Liang, 2011, PloS one.

In silico prediction of cytochrome P450-mediated site of metabolism (SOM).

Cheng Luo, Weiliang Zhu, Jing Li, 2013, Protein and peptide letters.

Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: A Combined Computational and Experimental Study.

Liang Li, Pan Deng, Mingyue Zheng, 2017, Journal of medicinal chemistry.

Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms

Cheng Luo, Mingyue Zheng, Hualiang Jiang, 2015, Scientific Reports.

(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice

Jing Chen, Jiming Ye, Mingyue Zheng, 2012, PloS one.

Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOT1L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-l-methionine (SAM)-Dependent Methyltransferase Family.

Hao Jiang, Cheng Luo, Mingyue Zheng, 2017, Journal of medicinal chemistry.

Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.

Honglin Li, Kunqian Yu, Mingyue Zheng, 2009, Journal of medicinal chemistry.

Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.

Weiliang Zhu, Jian Li, Mingyue Zheng, 2006, Bioorganic & medicinal chemistry letters.

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

Cheng Luo, Mingyue Zheng, Kaixian Chen, 2014, Journal of medicinal chemistry.

RD-Metabolizer: an integrated and reaction types extensive approach to predict metabolic sites and metabolites of drug-like molecules

Honglin Li, Mingyue Zheng, Shiliang Li, 2017, Chemistry Central Journal.

Deep Neural Network Classifier for Virtual Screening Inhibitors of (S)-Adenosyl-L-Methionine (SAM)-Dependent Methyltransferase Family

Zhaojun Li, Mingyue Zheng, Wencong Lu, 2019, Front. Chem..

Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.

Cheng Luo, Weiliang Zhu, Mingyue Zheng, 2012, Organic & biomolecular chemistry.

Recent Advances in Neuraminidase Inhibitor Development as Anti‐influenza Drugs

Fei Zhao, Mingyue Zheng, Rolf Hilgenfeld, 2012, ChemMedChem.

Predicting Hepatotoxicity of Drug Metabolites Via an Ensemble Approach Based on Support Vector Machine

Mingyue Zheng, Hualiang Jiang, Kaixian Chen, 2017, Combinatorial chemistry & high throughput screening.

Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.

Weiliang Zhu, Jian Li, Mingyue Zheng, 2013, Journal of medicinal chemistry.

AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo

Yang Yang, Mingyue Zheng, Hua Xie, 2011, PloS one.

Cholesterol‐β1AR interaction versus cholesterol‐β2AR interaction

Cheng Luo, Kunqian Yu, Mingyue Zheng, 2014, Proteins.

Combinatorial pharmacophore modeling of organic cation transporter 2 (OCT2) inhibitors: insights into multiple inhibitory mechanisms.

Cheng Luo, Hualiang Jiang, Mingyue Zheng, 2013, Molecular pharmaceutics.

In silico ADME/T modelling for rational drug design

Cheng Luo, Mingyue Zheng, Hualiang Jiang, 2015, Quarterly Reviews of Biophysics.

Computational Approaches in Drug Discovery and

Weiliang Zhu, Mingyue Zheng, Mingyue Zheng, 2008 .

Prediction of Drug Indications Based on Chemical Interactions and Chemical Similarities

Yu-Dong Cai, Mingyue Zheng, Guohua Huang, 2015, BioMed research international.

Discovery of new non-steroidal FXR ligands via a virtual screening workflow based on Phase shape and induced fit docking.

Weihua Li, Mingyue Zheng, Yun Tang, 2012, Bioorganic & medicinal chemistry letters.

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

Cheng Luo, Mingyue Zheng, Yaxi Yang, 2017, Organic & biomolecular chemistry.