Jianhua Shen

发表

Empowering Chinese Teaching with Technology-- A Yale Practice

Ling Mu, Rongzhen Li, Jianhua Shen, 2007 .

Conformational transition of amyloid beta-peptide.

Jianpeng Ma, Weiliang Zhu, Hualiang Jiang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Molecular insight into the interaction between IFABP and PA by using MM-PBSA and alanine scanning methods.

Cheng Luo, Weiliang Zhu, Hanjun Zou, 2007, The journal of physical chemistry. B.

Structure-based de novo design, synthesis, and biological evaluation of the indole-based PPARgamma ligands (I).

Xu Shen, Ren Wen, Jianhua Shen, 2006, Bioorganic & medicinal chemistry letters.

Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization

Li Du, Jing Chen, Xu Shen, 2005, Journal of Biological Chemistry.

The conserved residue Phe273(282) of PPARα(γ), beyond the ligand-binding site, functions in binding affinity through solvation effect

Fei Ye, Xu Shen, Hualiang Jiang, 2005 .

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Bing Xiong, Kaixian Chen, Jianhua Shen, 2002, Journal of medicinal chemistry.

Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations.

Weiliang Zhu, Kunqian Yu, Hualiang Jiang, 2007, Biophysical journal.

Inhibitory mode of indole-2-carboxamide derivatives against HLGPa: molecular docking and 3D-QSAR analyses.

Hong Liu, Xu Shen, Hualiang Jiang, 2004, Bioorganic & medicinal chemistry.

How does huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations.

Joel L Sussman, Hualiang Jiang, Kaixian Chen, 2003, Journal of the American Chemical Society.

Molecular docking and 3D QSAR studies on 1-amino-2-phenyl-4-(piperidin-1-yl)-butanes based on the structural modeling of human CCR5 receptor.

Cheng Luo, Hong Liu, Hualiang Jiang, 2004, Bioorganic & medicinal chemistry.

Conformational dynamics of the nicotinic acetylcholine receptor channel: a 35-ns molecular dynamics simulation study.

Hualiang Jiang, Kaixian Chen, Jianhua Shen, 2005, Journal of the American Chemical Society.

How does ammonium dynamically interact with benzene in aqueous media? A first principle study using the Car-Parrinello molecular dynamics method.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2006, The journal of physical chemistry. B.

Quantum Chemistry Study on the Interaction of the Exogenous Ligands and the Catalytic Zinc Ion in Matrix Metalloproteinases

Weiliang Zhu, Jiande Gu, Xin Li, 2002 .

Molecular Dynamics Simulations on SDF-1α: Binding with CXCR4 Receptor

Lingling Shen, Gang Pei, Hualiang Jiang, 2003 .

Discovery of novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling.

Ying Leng, Jianhua Shen, Jianhua Shen, 2008, Bioorganic & medicinal chemistry letters.

Structure-based discovery of potassium channel blockers from natural products: virtual screening and electrophysiological assay testing.

Yang Li, Jianmin Yue, Suxin Zheng, 2003, Chemistry & biology.

Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro

Christian Drosten, Burkhard Ludewig, Elke Scandella, 2005, Journal of Virology.

Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with β-secretase

Zhili Zuo, Weiliang Zhu, Xu Shen, 2005 .

Computational analysis of molecular basis of 1:1 interactions of NRG‐1β wild‐type and variants with ErbB3 and ErbB4

Cheng Luo, Mingdong Zhou, Suxin Zheng, 2005, Proteins.

Molecular dynamics simulations on SDF-1alpha: binding with CXCR4 receptor.

Lingling Shen, Gang Pei, Hualiang Jiang, 2003, Biophysical journal.

Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.

Weiliang Zhu, Yang Li, Suxin Zheng, 2007, Journal of medicinal chemistry.

Molecular docking and 3-D-QSAR studies on the possible antimalarial mechanism of artemisinin analogues.

Weiliang Zhu, Jiande Gu, Hualiang Jiang, 2002, Bioorganic & medicinal chemistry.

Molecular dynamics of nicotinic acetylcholine receptor correlating biological functions.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2006, Current protein & peptide science.

Discovering Severe Acute Respiratory Syndrome Coronavirus 3CL Protease Inhibitors: Virtual Screening, Surface Plasmon Resonance, and Fluorescence Resonance Energy Transfer Assays

Xu Shen, Jianhua Shen, Shuai Chen, 2006, SLAS Discovery.

Conformational transition of amyloid β-peptide

Jianpeng Ma, Weiliang Zhu, Hualiang Jiang, 2005 .

N-methylformamide-benzene complex as a prototypical peptide N-H...pi hydrogen-bonded system: density functional theory and MP2 studies.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2003, The Journal of organic chemistry.

Structure-based virtual screening for identification of novel 11beta-HSD1 inhibitors.

Ying Leng, Jianhua Shen, Jianhua Shen, 2009, European journal of medicinal chemistry.

Structure-based virtual screening for identification of novel 11 beta-HSD1 inhibitors

Ying Leng, Jianhua Shen, Jing Chen, 2009 .

In vitro biochemical and thermodynamic characterization of nucleocapsid protein of SARS

Fei Ye, Jing Chen, Xu Shen, 2004, Biophysical Chemistry.

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A

Cheng Luo, Jingkang Shen, Suxin Zheng, 2004, Biochemical and Biophysical Research Communications - BBRC.

GAsDock: a new approach for rapid flexible docking based on an improved multi-population genetic algorithm.

Honglin Li, Kaixian Chen, Jianhua Shen, 2004, Bioorganic & medicinal chemistry letters.

Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation.

Weiliang Zhu, Joel L Sussman, Hualiang Jiang, 2005, The journal of physical chemistry. B.

Blocking of the nicotinic acetylcholine receptor ion channel by chlorpromazine, a noncompetitive inhibitor: A molecular dynamics simulation study.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2006, The journal of physical chemistry. B.

POSSIBLE PATHWAY(S) OF TESTOSTERONE EGRESS FROM THE ACTIVE SITE OF CYTOCHROME P450 2B1: A STEERED MOLECULAR DYNAMICS SIMULATION

Weihua Li, Frauke Gräter, Hualiang Jiang, 2005, Drug Metabolism and Disposition.

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

Qiufeng Liu, Jianhua Shen, Yechun Xu, 2017, Journal of medicinal chemistry.

Design, Synthesis, and Structure–Activity Relationships of 3,4,5‐Trisubstituted 4,5‐Dihydro‐1,2,4‐oxadiazoles as TGR5 Agonists

Ying Feng, Junjie Zhu, Ying Leng, 2013, ChemMedChem.