David V Schaffer

发表

Bringing next-generation therapeutics to the clinic through synthetic biology.

Lukasz J Bugaj, David V Schaffer, D. Schaffer, 2012, Current opinion in chemical biology.

Response to “HIV Escape From RNAi Antivirals: Yet Another Houdini Action?”

David V Schaffer, Priya S Shah, 2012, Molecular therapy. Nucleic acids.

Mutual Information Analysis Reveals Coevolving Residues in Tat That Compensate for Two Distinct Functions in HIV-1 Gene Expression*

Qiang Zhou, Adam P Arkin, David V Schaffer, 2012, The Journal of Biological Chemistry.

Corrigendum to “Engineered viral vectors for functional interrogation, deconvolution, and manipulation of neural circuits” [Curr. Opin. Neurobiol. 50 (2018) 163–170]

David V Schaffer, Sabrina Sun, 2018, Current Opinion in Neurobiology.

PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation

David V Schaffer, D. Schaffer, J. Peltier, 2007, Developmental neurobiology.

Computational and experimental analysis of DNA shuffling

Narendra Maheshri, David V Schaffer, D. Schaffer, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Molecular engineering of viral gene delivery vehicles.

David V Schaffer, D. Schaffer, J. T. Koerber, 2008, Annual review of biomedical engineering.

Presentation counts: microenvironmental regulation of stem cells by biophysical and material cues.

Albert J. Keung, David V Schaffer, Albert J Keung, 2010, Annual review of cell and developmental biology.

Orthogonal control of expression mean and variance by epigenetic features at different genomic loci

Adam P Arkin, Jonathan E Foley, Jonathan E. Foley, 2015, Molecular systems biology.

In vivo genome editing improves motor function and extends survival in a mouse model of ALS

David V Schaffer, Thomas Gaj, D. Schaffer, 2017, Science Advances.

Challenging Regeneration to Transform Medicine

David V Schaffer, D. Schaffer, A. Tsukamoto, 2016, Stem cells translational medicine.

X‐Space MPI: Magnetic Nanoparticles for Safe Medical Imaging

Emine Ulku Saritas, Tyson N. Kim, Patrick William Goodwill, 2012, Advanced materials.

The biology and engineering of stem‐cell control

David V Schaffer, Analeah O'Neill, 2004, Biotechnology and applied biochemistry.

At Light Speed: Advances in Optogenetic Systems for Regulating Cell Signaling and Behavior.

Ravi S Kane, David V Schaffer, D. Schaffer, 2017, Annual review of chemical and biomolecular engineering.

Optogenetic protein clustering and signaling activation in mammalian cells

Ravi S Kane, Lukasz J Bugaj, David V Schaffer, 2013, Nature Methods.

Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells.

Albert J. Keung, Prashanth Asuri, David V Schaffer, 2012, Integrative biology : quantitative biosciences from nano to macro.

Progress and prospects for stem cell engineering.

Albert J. Keung, David V Schaffer, Randolph S Ashton, 2011, Annual review of chemical and biomolecular engineering.

Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells.

Jae-Hyung Jang, Prashanth Asuri, David V Schaffer, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Quantitative Magnetic Particle Imaging Monitors the Transplantation, Biodistribution, and Clearance of Stem Cells In Vivo

Bo Zheng, Beliz Gunel, David V Schaffer, 2016, Theranostics.

Designing synthetic materials to control stem cell phenotype.

Krishanu Saha, Kevin E Healy, David V Schaffer, 2007, Current opinion in chemical biology.

In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

Deniz Dalkara, Meike Visel, John G Flannery, 2013, Science Translational Medicine.

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.

Deniz Dalkara, Meike Visel, John G Flannery, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

High‐Throughput Screening of Gene Function in Stem Cells Using Clonal Microarrays

Sally Temple, Ravi S Kane, David V Schaffer, 2007, Stem cells.

Varying virulence: epigenetic control of expression noise and disease processes.

Adam P Arkin, Kathryn Miller-Jensen, David V Schaffer, 2011, Trends in biotechnology.

Substrate modulus directs neural stem cell behavior.

Albert J. Keung, Krishanu Saha, Yang Li, 2008, Biophysical journal.

Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration properties

David V Schaffer, D. Schaffer, Kwang-il Lim, 2010, Proceedings of the National Academy of Sciences.

Viral Vectors for Gene Therapy: Translational and Clinical Outlook.

David V Schaffer, D. Schaffer, M. Kotterman, 2015, Annual review of biomedical engineering.

The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells.

Ravi S Kane, Akhilesh Banerjee, David V Schaffer, 2009, Biomaterials.

Developing Defined and Scalable 3D Culture Systems for Culturing Human Pluripotent Stem Cells at High Densities

Yuguo Lei, David V Schaffer, D. Schaffer, 2014, Cellular and molecular bioengineering.

The AAV Vector Toolkit: Poised at the Clinical Crossroads.

David V Schaffer, D. Schaffer, A. Asokan, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

HIV evades RNA interference directed at TAR by an indirect compensatory mechanism.

Joshua N Leonard, David V Schaffer, Priya S Shah, 2008, Cell host & microbe.