Ralf Takors

发表

Model Discrimination and Parameter Identification by an Experimental Design Strategy

Ralf Takors, Dirk Weuster-Botz, Wolfgang Wiechert, 1998 .

Open Access for the future

Ralf Takors, An-Ping Zeng, Thomas Bley, 2020, Engineering in life sciences.

Predictability of kLa in stirred tank reactors under multiple operating conditions using an Euler–Lagrange approach

Ralf Takors, Johannes Wutz, Alexey Lapin, 2016 .

MMT - A pathway modeling tool for data from rapid sampling experiments

Ralf Takors, Wolfgang Wiechert, Jochen Hurlebaus, 2002, Silico Biol..

Automatic network generation describes differential gene data in user friendly and expeditiously analyzable network views

Ralf Takors, Sebastian Wolf, Sara Barbosa, 2017 .

MMT - A Metabolic Modeling Tool for Metabolic Engineering

Ralf Takors, Wolfgang Wiechert, Jochen Hurlebaus, 2001, German Conference on Bioinformatics.

Investigating the dynamic behavior of biochemical networks using model families

Bernd Freisleben, Ralf Takors, Wolfgang Wiechert, 2005, Bioinform..

Dynamic Simulation and Experimental Validation of pCO2-induced Population Heterogeneity

Ralf Takors, M. Kuschel, A. Eilingsfeld, 2016 .

Editorial: How can we ensure the successful transfer from lab‐ to large‐scale production?

Ralf Takors, 2016 .

Bioprocess scale‐up/down as integrative enabling technology: from fluid mechanics to systems biology and beyond

Ralf Takors, Henk Noorman, Frank Delvigne, 2017, Microbial biotechnology.

Metabolic and Bioprocess Engineering - a Fruitful Symbiosis

Ralf Takors, 2005 .

Grand Research Challenges for Sustainable Industrial Biotechnology.

Ralf Takors, Nick Wierckx, Adrie J J Straathof, 2019, Trends in biotechnology.

A guide to gene regulatory network inference for obtaining predictive solutions: Underlying assumptions and fundamental biological and data constraints

Ralf Takors, Sebastian Wolf, Klaus Mauch, 2018, Biosyst..

Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors.

Ralf Takors, Christopher Sarkizi Shams Hajian, Julia Zieringer, 2020, Advances in biochemical engineering/biotechnology.

Engineering mindset for Life Sciences and Biotechnology

Ralf Takors, An-Ping Zeng, Thomas Bley, 2019, Engineering in life sciences.

Modeling of gas–liquid mass transfer in a stirred tank bioreactor agitated by a Rushton turbine or a new pitched blade impeller

Ralf Takors, Ricardo Gelves, A Dietrich, 2014, Bioprocess and Biosystems Engineering.

Distributed Simulation of Metabolic Networks with Model Variants

Bernd Freisleben, Ralf Takors, Wolfgang Wiechert, 2002, ESM.

Transcriptional response of Escherichia coli to ammonia and glucose fluctuations

Oliver Sawodny, Ralf Takors, Ronny Feuer, 2017, Microbial biotechnology.

Repetitive Short-Term Stimuli Imposed in Poor Mixing Zones Induce Long-Term Adaptation of E. coli Cultures in Large-Scale Bioreactors: Experimental Evidence and Mathematical Model

Ralf Takors, Michael Löffler, Alexander Nieß, 2017, Front. Microbiol..

Principal-component analysis for microbial L-phenylalanine production

Ralf Takors, Christian Wandrey, M. Gerigk, 2001 .

Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments.

Ralf Takors, Wolfgang Wiechert, Katharina Nöh, 2007, Journal of biotechnology.

Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry.

Ralf Takors, Marco Oldiges, Karsten Groenke, 2007, Journal of chromatography. A.

The identification of enzyme targets for the optimization of a valine producing Corynebacterium glutamicum strain using a kinetic model

Ralf Takors, Marco Oldiges, R. Takors, 2009, Biotechnology progress.

Monitoring and Modeling of the Reaction Dynamics in the Valine/Leucine Synthesis Pathway in Corynebacterium glutamicum

Ralf Takors, Marco Oldiges, R. Takors, 2006, Biotechnology progress.

Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in Large-Scale Bioreactors

Ralf Takors, Flora Siebler, Maike Kuschel, 2017, Bioengineering.

Platform Engineering of Corynebacterium glutamicum with Reduced Pyruvate Dehydrogenase Complex Activity for Improved Production of l-Lysine, l-Valine, and 2-Ketoisovalerate

Ralf Takors, R. Takors, A. Schwentner, 2013, Applied and Environmental Microbiology.

Serial 13C‐Based Flux Analysis of an l‐Phenylalanine‐Producing E. coli Strain Using the Sensor Reactor

Ralf Takors, Wolfgang Wiechert, Aljoscha Wahl, 2004, Biotechnology progress.

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments

Ralf Takors, Marco Oldiges, Christoph Wittmann, 2007, Metabolomics.

Valorization of pyrolysis water: a biorefinery side stream, for 1,2-propanediol production with engineered Corynebacterium glutamicum

Ralf Takors, Nicolaus Dahmen, R. Takors, 2017, Biotechnology for Biofuels.

Using gas mixtures of CO, CO2 and H2 as microbial substrates: the do's and don'ts of successful technology transfer from laboratory to production scale

Ralf Takors, Michael Kopf, Peter Dürre, 2018, Microbial biotechnology.

Engineering E. coli for large-scale production - Strategies considering ATP expenses and transcriptional responses.

Ralf Takors, Günter Jäger, R. Takors, 2016, Metabolic engineering.

CO2/HCO3− perturbations of simulated large scale gradients in a scale-down device cause fast transcriptional responses in Corynebacterium glutamicum

Ralf Takors, Tobias Busche, Jörn Kalinowski, 2014, Applied Microbiology and Biotechnology.

Environmental stress speeds up DNA replication in Pseudomonas putida in chemostat cultivations

Ralf Takors, Joachim Koepff, Susann Müller, 2016, Biotechnology journal.

Application of model discriminating experimental design for modeling and development of a fermentative fed-batch L-valine production process.

Ralf Takors, Christian Wandrey, R. Takors, 2005, Biotechnology and bioengineering.

Escherichia coli HGT: Engineered for high glucose throughput even under slowly growing or resting conditions.

Ralf Takors, Martin Siemann-Herzberg, R. Takors, 2017, Metabolic engineering.

Switching between nitrogen and glucose limitation: Unraveling transcriptional dynamics in Escherichia coli.

Ralf Takors, Günter Jäger, R. Takors, 2017, Journal of biotechnology.

Sensitivity analysis for the reduction of complex metabolism models

Ralf Takors, Gerhard Dikta, R. Takors, 2004 .