Mauro W. Costa

发表

VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery

Hiroaki Kitano, Nadia A. Rosenthal, Sarah E. Boyd, 2015, BMC Bioinformatics.

CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts

Milena B. Furtado, Mauro W. Costa, H. Kitano, 2015, PloS one.

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.

Mauro W. Costa, B. Bruneau, D. Elliott, 2003, Developmental biology.

Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2011, PloS one.

A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery

Milena B. Furtado, Mauro W. Costa, D. Elliott, 2006, Development.

Effect of Oxygen on Cardiac Differentiation in Mouse iPS Cells: Role of Hypoxia Inducible Factor-1 and Wnt/Beta-Catenin Signaling

Milena B. Furtado, Mauro W. Costa, T. Medley, 2013, PloS one.

Molecular analysis of PRKAG2, LAMP2, and NKX2‐5 genes in a cohort of 125 patients with accessory atrioventricular connection

Mauro W. Costa, R. Harvey, B. Dallapiccola, 2009, American journal of medical genetics. Part A.

Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2013, Circulation. Cardiovascular genetics.

FUNCTIONAL CHARACTERIZATION OF A NOVEL MUTATION IN NKX 2-5 ASSOCIATED WITH CONGENITAL HEART DISEASE AND ADULT-ONSET CARDIOMYOPATHY . Costa : NKX 2-5 mutation in familial DCM

Milena B. Furtado, Mauro W. Costa, J. Seidman, 2015 .

Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases.

Mauro W. Costa, E. Mattos, Juliana Camacho-Pereira, 2012, Experimental and clinical cardiology.

Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5.

Mauro W. Costa, D. Elliott, Norma A S Almeida, 2004, Cardiovascular research.

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.

Mauro W. Costa, C. Hayward, D. Fatkin, 2007, American journal of human genetics.

Adult fibroblasts retain organ-specific transcriptomic identity

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2021, bioRxiv.

Fibroblast organ code 1 Adult mouse fibroblasts retain organ-specific transcriptomic identity 1 2

Mauro W. Costa, N. Rosenthal, E. Stanley, 2022 .

Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy

Mauro W. Costa, J. C. Fierro-González, J. Polo, 2013, Nature Communications.

Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

Mauro W. Costa, R. Harvey, F. Kober, 2018, PLoS genetics.

Molecular Tools in Cancer Research

Mauro W. Costa, N. Rosenthal, 2020, Abeloff's Clinical Oncology.

3D-Cardiomics: A spatial transcriptional atlas of the mammalian heart

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2019, bioRxiv.

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

Milena B. Furtado, Mauro W. Costa, S. Murray, 2017, JCI insight.

Transcription factor protein interactomes reveal genetic determinants in heart disease

Mauro W. Costa, K. Pollard, N. Krogan, 2022, Cell.

GATA4 mutations in 357 unrelated patients with congenital heart malformation.

Mauro W. Costa, L. Waddell, R. Harvey, 2010, Genetic testing and molecular biomarkers.

A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.

Michael P. Eichenlaub, Milena B. Furtado, Mauro W. Costa, 2016, Differentiation; research in biological diversity.

BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4.

Milena B. Furtado, Mauro W. Costa, S. Dunwoodie, 2008, Genes & development.

3D-cardiomics: A spatial transcriptional atlas of the mammalian heart.

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2021, Journal of molecular and cellular cardiology.

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Mauro W. Costa, R. Passier, C. Mummery, 2018, Nature Communications.

Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2018, bioRxiv.

Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2014, Circulation research.

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Milena B. Furtado, Mauro W. Costa, D. Fatkin, 2005, Development.

Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20.

Mauro W. Costa, J. Mackay, R. Harvey, 2009, Journal of molecular biology.

The cardiac fibroblast: Origin, identity and role in homeostasis and disease.

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2016, Differentiation; research in biological diversity.

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Mauro W. Costa, R. Passier, C. Mummery, 2018, Nature Communications.

Correction: Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

Mauro W. Costa, R. Harvey, F. Kober, 2018, PLoS genetics.

Homeodomain factor Nkx2-5 in heart development and disease.

Milena B. Furtado, Mauro W. Costa, D. Elliott, 2002, Cold Spring Harbor symposia on quantitative biology.

Microarray profiling to analyse adult cardiac fibroblast identity

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2014, Genomics data.

Rationale: Cardiac Fibroblasts Are Critical to Proper Heart Function through Multiple Interactions with the Myocardial Compartment, but Appreciation of Their Contribution Has Suffered from Incomplete Characterization and Lack of Cell-specific Markers. Methods and Results: High-throughput Cell Surfac

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2022 .

Correction: Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

Mauro W. Costa, R. Harvey, F. Kober, 2018, PLoS Genetics.